2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species
  4. Chlorin e6 trimethyl ester

Chlorin e6 trimethyl ester, a methyl pheophorbide-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT).

For research use only. We do not sell to patients.

Chlorin e6 trimethyl ester Chemical Structure

Chlorin e6 trimethyl ester Chemical Structure

CAS No. : 35038-32-5

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Based on 1 publication(s) in Google Scholar

Chlorin e6 trimethyl ester Related Antibodies

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1 Publications Citing Use of MCE Chlorin e6 trimethyl ester

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Description

Chlorin e6 trimethyl ester, a methyl pheophorbide-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT)[1][2].

In Vivo

Chlorin e6 trimethyl ester (5 mg/kg; i.p.) has no tumorcidal activity in mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

638.75

Formula

C37H42N4O6
CAS No.
Appearance

Solid

Color

Brown to black

SMILES

O=C(OC)C/C(C(NC(/C=C1C(CC)=C2C)=C3C)=C3C(OC)=O)=C(N=C(/C=C(C(C)=C/4C=C)\NC4=C/C2=N/1)[C@H]5C)\[C@H]5CCC(OC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (15.66 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5656 mL 7.8278 mL 15.6556 mL
5 mM 0.3131 mL 1.5656 mL 3.1311 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.81%

COA (263 KB) HNMR (314 KB) LCMS (96 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5656 mL 7.8278 mL 15.6556 mL 39.1389 mL
5 mM 0.3131 mL 1.5656 mL 3.1311 mL 7.8278 mL
10 mM 0.1566 mL 0.7828 mL 1.5656 mL 3.9139 mL
15 mM 0.1044 mL 0.5219 mL 1.0437 mL 2.6093 mL
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Chlorin e6 trimethyl ester Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chlorin e6 trimethyl ester35038-32-5Reactive Oxygen Speciesmethylpheophorbide-aderivativephotosensitizerphotodynamictherapyPDTInhibitorinhibitorinhibit

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