country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-147690

Copy Link Print Information

Photosensitizer-2

Photosensitizer-2 (compound 1) is a organic D-π-A sensitizer against phototoxicity. Photosensitizer-2 contains an acrylic acid moiety that exerts high levels of phototoxicity. Photosensitizer-2 shows antitumor activity against HeLa cells, with IC₅₀ values of 20.9 ± 4.5 μM (dark) and 0.046 ± 0.012 μM (irradiation), respectively.

For research use only. We do not sell to patients.

CAS No.: 2138330-43-3
Formula: C₂₉H₂₁NO₂S₂
Molecular Weight:479.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Photosensitizer-2 Chemical Structure

CAS No.: 2138330-43-3

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	0.046 μM Compound: 1	Phototoxicity against human HeLa cells assessed as reduction in cell viability preincubated for 1 hr followed by white LED irradiation for 15 mins and measured after 48 hrs by MTT assay Phototoxicity against human HeLa cells assessed as reduction in cell viability preincubated for 1 hr followed by white LED irradiation for 15 mins and measured after 48 hrs by MTT assay	[PMID: 32546300]
HeLa	IC₅₀	13.8 μM Compound: 1	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs measured under dark conditions by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs measured under dark conditions by MTT assay	[PMID: 32546300]

Chemical Information

CAS No. 2138330-43-3
Molecular Weight 479.61
Formula C₂₉H₂₁NO₂S₂
SMILES

O=C(/C=C/C1=CC=C(S1)C2=CC=C(S2)C3=CC=C(C=C3)N(C4=CC=CC=C4)C5=CC=CC=C5)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fuse S, Moriya W, Sato S, Nakamura H. Investigation into the influence of an acrylic acid acceptor in organic D-π-A sensitizers against phototoxicity. Bioorg Med Chem. 2020 Jul 1;28(13):115558. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote