Cypate hydrochloride
Based on 1 publication(s) in Google Scholar
Cypate is a near-infrared fluorescent dye that belongs to the family of photosensitizers. Cypate has high photostability and optical properties, and is often used in near-infrared optical imaging, as well as optical imaging, tumor marking, and drug delivery. In addition, Cypate is also used as a molecular probe and combined with targeting molecules (such as CBT or small interfering RNA) to achieve efficient detection and imaging of specific cells or tissues.
For research use only. We do not sell to patients.
- Purity: 98.60%
- Formula: C41H41ClN2O4
- Molecular Weight:661.23
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Cypate hydrochloride
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Biological Activity
In the study, Cypate coupled upconversion nanoparticles (UCNP-cy) loaded with small interfering RNA gene with anti-heat shock protein 70 (UCNP-cy-siRNA) resulted in targeted cell damage and anti-tumor effects[1].
Cypate can also be coupled to CBT (Cysteine-containing Peptide Backbone Tag), which can be used to track, label and image specific biomolecules or cells. For example, Cypate-CBT, as a near-infrared photoacoustic (PA) probe, can be used to specifically image and track cathepsin B (CTSB) activity in CTSB-overexpressing cells and tumors in real time. After Cypate-CBT entered CTSB overexpressing cells, it underwent glutathione reduction and CTSB cleavage to generate cypate nanoparticles Cypate-CBT-NPs, which enhanced the intensity and retention time of PA signal at tumor sites. Cypate-CBT has the potential to be used as an effective PA imaging agent for clinical diagnosis of early cancer[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 661.23
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Formula C41H41ClN2O4
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Color Green to dark green
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SMILES
O=C(CC[N+]1=C(/C=C/C=C/C=C/C=C2N(CCC(O)=O)C3=C(C/2(C)C)C4=C(C=CC=C4)C=C3)C(C)(C)C5=C1C=CC6=C5C=CC=C6)[O-].[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Mater Today Bio
An exosome-biomimetic photothermal nanocarrier for IGF2BP2 siRNA delivery and enhanced ferroptosis in head and neck squamous cell carcinoma. [Abstract]2026 Mar 5:37:102999. PMID: 41859644
Solvent & Solubility
DMSO : 12.5 mg/mL (18.90 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5123 mL | 7.5617 mL | 15.1233 mL | 37.8083 mL |
| 5 mM | 0.3025 mL | 1.5123 mL | 3.0247 mL | 7.5617 mL | |
| 10 mM | 0.1512 mL | 0.7562 mL | 1.5123 mL | 3.7808 mL | |
| 15 mM | 0.1008 mL | 0.5041 mL | 1.0082 mL | 2.5206 mL |
Cypate hydrochloride Related Classifications
HY-D1719A Related Classifications
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