Methylene Violet 3RAX
Based on 1 Customer Validation
Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an Kis of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 95.54%
- No. CAS: 4569-86-2
- Fòrmula: C22H23ClN4
- Peso molecular:378.90
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Almacenamiento:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[2]|
BChE 0.51 μM (Ki) |
AChE 1.58 μM (Ki) |
In Vitro
Methylene Violet 3RAX shows antitumor activity by cutting off DNA strands in tumour cell[1]. Methylene Violet 3RAX (0-400 µM) significantly enhances cleavage of DNA with over 60% photocleavage activity towards DNA at 300 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 4569-86-2
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Appearance Powder
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Peso molecular 378.90
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Fòrmula C22H23ClN4
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Color Green to dark green
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SMILES
[Cl-].N=1C=2C=CC(N)=CC2[N+](C=3C=CC=CC3)=C4C=C(C=CC14)N(CC)CC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvente y solubilidad
In Vitro:
DMSO : 25 mg/mL (65.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6392 mL | 13.1961 mL | 26.3922 mL | 65.9805 mL |
| 5 mM | 0.5278 mL | 2.6392 mL | 5.2784 mL | 13.1961 mL | |
| 10 mM | 0.2639 mL | 1.3196 mL | 2.6392 mL | 6.5980 mL | |
| 15 mM | 0.1759 mL | 0.8797 mL | 1.7595 mL | 4.3987 mL | |
| 20 mM | 0.1320 mL | 0.6598 mL | 1.3196 mL | 3.2990 mL | |
| 25 mM | 0.1056 mL | 0.5278 mL | 1.0557 mL | 2.6392 mL | |
| 30 mM | 0.0880 mL | 0.4399 mL | 0.8797 mL | 2.1993 mL | |
| 40 mM | 0.0660 mL | 0.3299 mL | 0.6598 mL | 1.6495 mL | |
| 50 mM | 0.0528 mL | 0.2639 mL | 0.5278 mL | 1.3196 mL | |
| 60 mM | 0.0440 mL | 0.2199 mL | 0.4399 mL | 1.0997 mL |
Methylene Violet 3RAX Related Classifications
HY-W130236 Related Classifications
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