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Cat. No.: HY-145265

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Antimicrobial photosensitizer-1

Antimicrobial photosensitizer-1 is a promising candidate as the antimicrobial photosensitizer for combating pathogenic microorganism infections. Antimicrobial photosensitizer-1 exhibits an impressive antimicrobial efficacy in S. aureus-infected mice wounds.

For research use only. We do not sell to patients.

CAS No.: 2933179-62-3
Formula: C₁₉H₁₉BF₂I₃N₃
Molecular Weight:718.90

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Antimicrobial photosensitizer-1 Chemical Structure

CAS No.: 2933179-62-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HaCaT	IC₅₀	3.86 μM Compound: 3c	Cytotoxicity against human HaCat Cells assessed as reduction in cell survival preincubated for 15 mins followed by irradiated with light at 81 J/cm^2 for 15 mins and measured after 24 hrs by CCK-8 assay Cytotoxicity against human HaCat Cells assessed as reduction in cell survival preincubated for 15 mins followed by irradiated with light at 81 J/cm^2 for 15 mins and measured after 24 hrs by CCK-8 assay	[PMID: 34881897]

Chemical Information

CAS No. 2933179-62-3
Molecular Weight 718.90
Formula C₁₉H₁₉BF₂I₃N₃
SMILES

C[N+]1=CC=CC(C2=C3[N](B(F)(F)N4C2=C(C)C(I)=C4C)=C(C)C(I)=C3C)=C1.[I-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lin G, et al. Discovery of Meso-(meta-Pyridinium) BODIPY Photosensitizers: In Vitro and In Vivo Evaluations for Antimicrobial Photodynamic Therapy. J Med Chem. 2021;64(24):18143-18157. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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