Search Result

Results for "

7-chloro-8-fluoropyrido[4,3-d]pyrimidine-2,4(1H,3H)-dione

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (1) Apoptosis (1) Bacterial (2) Bcl-2 Family (1) Biochemical Assay Reagents (11) Caspase (1) Cytochrome P450 (2) Drug Derivative (6) Drug Intermediate (21) Drug Metabolite (2) E3 Ligase Ligand-Linker Conjugates (1) Endogenous Metabolite (10) Ephrin Receptor (1) Fluorescent Dye (2) Fungal (1) Isotope-Labeled Compounds (8) Ligands for E3 Ligase (1) Microtubule/Tubulin (1) MOFs (12) Nucleoside Antimetabolite/Analog (4) Parasite (1) Phosphatase (1) Phosphodiesterase (PDE) (1) PROTAC Linkers (1) Reference Standards (10) RSV (1) SARS-CoV (1) STAT (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (17) Endocrinology (4) Infection (7) Inflammation/Immunology (4) Metabolic Disease (3) Neurological Disease (13)
Oligonucleotides:	Nucleoside Analogs (4)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W095670

2,4,7-Trichloro-8-fluoropyrido[4,3-d]pyrimidine	Drug Intermediate	Others
2,4,7-Trichloro-8-fluoropyridopyrimidine is a pyridopyrimidine synthetic intermediate of MRTX1133 (HY-134813), which can be used for the synthesis of non-covalent KRAS ^G12D inhibitors .

HY-W008510

2-Chloro-5-(trifluoromethyl)pyrimidine	Drug Intermediate STAT	Others
2-Chloro-5-(trifluoromethyl)pyrimidine is a chemical intermediate. It can be used in the synthesis of inducers of intracellular STAT1 phosphorylation .

HY-40351

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine	Drug Intermediate	Others
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a nitrogen-containing heterocyclic organic synthesis intermediate that can be used for the synthesis of JAK and PKB/Akt inhibitors .

HY-W018758

1-Phenylpropane-1,2-dione	SARS-CoV	Infection
1-Phenylpropane-1,2-dione is a SARS-CoV-2 helicase binder. 1-Phenylpropane-1,2-dione can be isolated from the young stems of Ephedra sinica. 1-Phenylpropane-1,2-dione is commonly used as an edible flavoring and a basic raw material in synthetic chemistry. 1-Phenylpropane-1,2-dione can be applied to research related to COVID-19 .

HY-W062171

Cyclo-(Pro-Gly) Pyrrolopiperazine-2,5-dione	Drug Derivative	Neurological Disease
Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae . Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions .

HY-Y0519

*Pyrimidine*	Endogenous Metabolite	Neurological Disease Cancer
Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .

HY-W012944

2-Methylcyclopentane-1,3-dione	Biochemical Assay Reagents	Others
2-Methylcyclopentane-1,3-dione is a synthon . 2-Methylcyclopentane-1,3-dione can be used for the synthesis of (±)-α-cuparenone .

HY-W006492

5a-Pregnane-3,20-dione 1 Publications Verification	Endogenous Metabolite	Endocrinology Cancer
5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

HY-W003486

5,7-Dichloropyrazolo[1,5-a]pyrimidine	Phosphodiesterase (PDE)	Neurological Disease Cancer
5,7-Dichloropyrazolo[1,5-a]pyrimidine is a PDE10A inhibitor with a K_i of 24 μM. 5,7-Dichloropyrazolo[1,5-a]pyrimidine serves as a key intermediate in the synthesis of 5,7-disubstituted pyrazolo[1,5-a]pyrimidine derivatives (HIV-1 non-nucleoside reverse transcriptase inhibitors). 5,7-Dichloropyrazolo[1,5-a]pyrimidine can be used for the research of schizophrenia .

HY-P10579

123B9 1 Publications Verification	Ephrin Receptor	Cancer
123B9, a tumor-homing agent, is a potent and selective EphA2 agonist with a K_d value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. 123B9 does not appreciably inhibit the ligand binding domains of the most closely related EphA3 and EphA4 receptors .

HY-Y0315

Hexane-2,5-dione 2,5-HD	Drug Metabolite Apoptosis Bcl-2 Family β-catenin Caspase Microtubule/Tubulin Wnt	Neurological Disease
Hexane-2,5-dione (2,5-HD) is an orally active, CNS-penetrant cytotoxic agent . Hexane-2,5-dione reduces BCL-2 and β-catenin/TCF transcriptional activity, increases BAX and active caspase-3 expression, and promotes apoptosis. Hexane-2,5-dione causes an accumulation of neurofilaments within axons in rats. Hexane-2,5-dione can be used for the research of neurodegenerative diseases .

HY-W007466

Cyclohexane-1,3-dione 1 Publications Verification	Drug Intermediate	Cancer
Cyclohexane-1,3-dione is a drug intermediate, and its derivatives can exhibit significant tyrosine kinase inhibitory activity and anti-tumor activity .

HY-W002404

Pyrimidine-4-carboxylic acid	Biochemical Assay Reagents	Others
Pyrimidine-4-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W178327

*8-Chloro* caffeine**	Adenosine Receptor	Cancer
8-Chloro caffeine binds to adenosine receptors (K_i = 30 µM). 8-Chloro caffeine potentiates UV-induced chromosomal aberrations in Cl-I Chinese hamster embryonic lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine .

HY-113302

19-Hydroxyandrost-4-ene-3,17-dione	Endogenous Metabolite	Others
19-Hydroxyandrost-4-ene-3,17-dione is a substrate for Corticotropin-lipotropin and Cytochrome P450 19A1.

HY-76558

*Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate*	Biochemical Assay Reagents Drug Intermediate	Others
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a drug intermediate. Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate can be used to synthesize inhibitors of various kinases such as Cdk4, PDGF, FGF, EGF .

HY-42451

*2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde*	Drug Intermediate	Others
2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde is a drug intermediate for synthesis of various active compounds.

HY-42450

*2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol* (2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol	Drug Intermediate	Others
2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol ((2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol) is a drug intermediate for synthesis of various active compounds.

HY-W006492S

*5a-Pregnane-3,20-dione-d6*	Endogenous Metabolite	Endocrinology Cancer
5a-Pregnane-3,20-dione-d₆ is the deuterium labeled 5a-Pregnane-3,20-dione. 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

HY-42045

Pyrimidine-5-boronic acid pinacol ester	Drug Derivative	Others
Pyrimidine-5-boronic acid pinacol ester is a derivative of Boronic acid. Boronic acid is an intermediate commonly used in organic synthesis reactions and can be used as a key reagent in the Suzuki-Miyaura reaction. It generates organic free radicals through oxygen-mediated oxidation and exhibits potential mutagenic activity. Boronic acid is mainly used in research in the fields of drug synthesis and catalytic reactions. Pyrimidine-5-boronic acid pinacol ester serves as a building block in DNA-compatible one-pot click chemistry for synthesis of DNA-encoded libraries .

HY-W102931

6,7-Dichloroquinoline-5,8-dione	Phosphatase	Cancer
6,7-Dichloroquinoline-5,8-dione (compound DA3002) is a potent CDC25B2 inhibitor with an IC₅₀ value of 4.6 µM. 6,7-Dichloroquinoline-5,8-dione has the potential for the research of cancer .

HY-W017769

*4-Pyrimidine* methanamine** Pyrimidin-4-ylmethanamine	Drug Intermediate	Others
4-Pyrimidine methanamine (Pyrimidin-4-ylmethanamine) is a synthetic intermediate useful for pharmaceutical synthesis.

HY-N7885

(25R)-Spirost-4-ene-3,12-dione (-)-(25R)-Spirost-4-ene-3,12-dione	Others	Inflammation/Immunology
(25R)-Spirost-4-ene-3,12-dione ((-)-(25R)-Spirost-4-ene-3,12-dione) is a natural product that has an inhibitory effect on neutrophil superoxide anion production and histamine release from mast cells .

HY-W027690

2-Bromo-cyclohexane-1,3-dione	Drug Intermediate	Others
2-Bromo-cyclohexane-1,3-dione is a drug intermediate for synthesis of various active compounds.

HY-W076794

3-Bromo-1H-pyrrole-2,5-dione	Bacterial	Infection
3-Bromo-1H-pyrrole-2,5-dione (compound 2c) is a 3-substituted pyrrole-2,5-dione compound with antibacterial activity. 3-Bromo-1H-pyrrole-2,5-dione inhibits pathogenic strains of S. aureus ATCC 25923, E. coli ATCC 25922, P. aeruginosa ATCC 27853, with MIC values of 32 μg/mL, 32 μg/mL, and 64 μg/mL, respectively .

HY-44072

7-Chloro-6-fluoro-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidine-2,4-dione	Drug Intermediate	Others
7-Chloro-6-fluoro-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidine-2,4-dione is a drug intermediate for synthesis of various active compounds.

HY-N1203

(5α)-Stigmastane-3,6-dione	Bacterial	Infection Inflammation/Immunology
(5α)-Stigmastane-3,6-dione is a naturally occurring sterol that could be isolated from fruits of Ailanthus altissima Swingle. Antimicrobial Activity. .

HY-Y0519R

Pyrimidine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Pyrimidine (Standard) is the analytical standard of Pyrimidine. This product is intended for research and analytical applications. Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .

HY-41832

4,6-Dichloro-2-(methylthio)pyrimidine	Biochemical Assay Reagents Drug Intermediate	Cancer
4,6-Dichloro-2-(methylthio)pyrimidine is an intermediate. 4,6-Dichloro-2-(methylthio)pyrimidine can be used to synthesize Kras modulators. 4,6-Dichloro-2-(methylthio)pyrimidine can be used in cancer research .

HY-N16513

Muurol-4-ene-3,8-dione	Others	Metabolic Disease
Muurol-4-ene-3,8-dione (Compound 2), a sesquiterpene, is one of the main hepatotoxic components in Eupatorium adenophorum. Muurol-4-ene-3,8-dione has an inhibitory effect on the growth of both the normal human hepatocyte cell L02 and the human hepatocellular carcinoma cell HepG2 with IC₅₀ values of 87.52 and 104.48 μM .

HY-W004464

2-(1-Piperazinyl)pyrimidine	Endogenous Metabolite	Neurological Disease
2-(1-Piperazinyl)pyrimidine is the major metabolite of Tandospirone (HY-14558) .

HY-W062171R

Cyclo-(Pro-Gly) (Standard) Pyrrolopiperazine-2,5-dione (Standard)	Reference Standards Others	Neurological Disease
Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae . Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions .

HY-33638

(2-Chloropyrimidin-5-yl)methanol 2-chloro-5-pyrimidinemethanol; 2-chloro-5-(hydroxymethyl)pyrimidine	Biochemical Assay Reagents	Others
(2-Chloropyrimidin-5-yl)methanol (2-Chloro-5-pyrimidinemethanol) is an inorganic catalyst .

HY-W002860

Cycloheptane-1,3-dione	Biochemical Assay Reagents Drug Intermediate	Cancer
Cycloheptane-1,3-dione (Compound 1A) is an intermediate. Cycloheptane-1,3-dione can be used to synthesize Compound 1-1. Compound 1-1 has anticancer activity against colon cancer .

HY-78337

*Methyl pyrimidine-2-carboxylate*	Biochemical Assay Reagents	Others
Methyl pyrimidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W012482

5-(tert-Butyl)isobenzofuran-1,3-dione	Fluorescent Dye	Others
5-(tert-Butyl)isobenzofuran-1,3-dione is a intermediate and dye. 5-(tert-Butyl)isobenzofuran-1,3-dione has a synonym of 4-tert-Butylphthalic Anhydride .

HY-52102

*2-(Chloromethyl)pyrimidine* hydrochloride**	Drug Intermediate	Others
2-(Chloromethyl)pyrimidine hydrochloride is a synthetic intermediate useful for pharmaceutical synthesis.

HY-W001851

1-Benzylpyrrole-2,5-dione N-Benzylmaleimide	Drug Intermediate	Others
1-Benzylpyrrole-2,5-dione (N-Benzylmaleimide) is a heterocyclic compound containing a maleimide ring and a benzyl group. 1-Benzylpyrrole-2,5-dione can be used as a key reactant for the green chemical modification of cellulose nanocrystals (CNC).

HY-24116

6,7-Dibromoquinoline-5,8-dione	Drug Intermediate	Others
6,7-Dibromoquinoline-5,8-dione is a drug intermediate for synthesis of various active compounds.

HY-136092

Androsta-1,4,6-triene-3,17-dione	Cytochrome P450	Neurological Disease Endocrinology
Androsta-1,4,6-triene-3,17-dione is a lipophilic and specific aromatase inhibitor with a K_i of 0.18 μM. Androsta-1,4,6-triene-3,17-dione inhibits estrogen biosynthesis and shows antifertility effects. Androsta-1,4,6-triene-3,17-dione induces impairment of spatial memory .

HY-W018758R

*1-Phenylpropane-1,2-dione* (Standard)**	Reference Standards Others	Others Metabolic Disease
1-Phenylpropane-1,2-dione, isolated from young Ephedra sinica Stapf (Ephedraceae), is biosynthetic precursors of the ephedrine alkaloids .

HY-152980

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152986

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152977

4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152818

4-Chloro-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine	Nucleoside Antimetabolite/Analog	Others
4-Chloro-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W043311

*Methyl pyrimidine-4-carboxylate* pyrimidine-4-carboxylicacidmethylester	Drug Intermediate	Others
Methyl pyrimidine-4-carboxylate (Pyrimidine-4-carboxylicacidmethylester) is a synthetic intermediate useful for pharmaceutical synthesis.

HY-P3178

Pyrimidine nucleoside phosphorylase	Biochemical Assay Reagents	Infection Cancer
Pyrimidine nucleoside phosphorylase is an enzyme. The Pyrimidine nucleoside phosphorylase in Mycoplasma hyorhinis efficiently catalyzes the phosphorylation of thymidine and uridine, and exhibits (2 ^,-deoxy)ribosyltransferase activity .

HY-W777266

*Cyclohexane-1,3-dione-13C3*	Isotope-Labeled Compounds Biochemical Assay Reagents	Others
Cyclohexane-1,3-dione- ¹³C₃ is the ¹³C-labeled Cyclohexane-1,3-dione (HY-W007466). Cyclohexane-1,3-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W777928

*Cyclohexane-1,3-dione-13C6*	Isotope-Labeled Compounds Biochemical Assay Reagents	Others
Cyclohexane-1,3-dione- ¹³C₆ is the ¹³C-labeled Cyclohexane-1,3-dione (HY-W007466). Cyclohexane-1,3-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-118295

Pyrimidine-indole hybrid	Endogenous Metabolite	Cancer
Pyrimidine-indole hybrid is a compound that inhibits ciliogenesis and has the activity of antagonizing the Hedgehog signaling pathway by destabilizing microtubules. Pyrimidine-indole hybrid exerts its biological effects by inhibiting ciliogenesis and deconstructing the stable form of α-tubulin. Pyrimidine-indole hybrid has shown its unique mechanism of action in in vitro cell experiments and zebrafish embryo models, interfering with microtubule dynamics .

Cat. No.	Product Name

HY-L044

Nucleotide Compound Library

575 compounds

Nucleoside and nucleotide analogues are synthetic, chemically modified compounds that have been developed to mimic their physiological counterparts in order to exploit cellular metabolism and subsequently be incorporated into DNA and RNA to inhibit cellular division and viral replication. In addition to their incorporation into nucleic acids, nucleoside and nucleotide analogues can interact with and inhibit essential enzymes such as human and viral polymerases (that is, DNA-dependent DNA polymerases, RNA-dependent DNA polymerases or RNA-dependent RNA polymerases), kinases, ribonucleotide reductase, DNA methyltransferases, purine and pyrimidine nucleoside phosphorylase and thymidylate synthase. These actions of nucleoside and nucleotide analogues have potential therapeutic benefits — for example, in the inhibition of cancer cell growth, the inhibition of viral replication as well as other indications.

MCE offers a unique collection of 575 nucleotide compounds including nucleotide, nucleoside and their structural analogues. MCE Nucleotide Compound Library is a useful tool to discover anti-cancer and antiviral drugs for high throughput screening (HTS) and high content screening (HCS).

Cat. No.	Product Name	Type

HY-40351

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine	Biochemical Assay Reagents
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine is a nitrogen-containing heterocyclic organic synthesis intermediate that can be used for the synthesis of JAK and PKB/Akt inhibitors .

HY-W007466

Cyclohexane-1,3-dione 1 Publications Verification	Biochemical Assay Reagents
Cyclohexane-1,3-dione is a drug intermediate, and its derivatives can exhibit significant tyrosine kinase inhibitory activity and anti-tumor activity .

HY-W002404

Pyrimidine-4-carboxylic acid	Biochemical Assay Reagents
Pyrimidine-4-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-76558

*Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate*	Biochemical Assay Reagents
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a drug intermediate. Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate can be used to synthesize inhibitors of various kinases such as Cdk4, PDGF, FGF, EGF .

HY-42045

Pyrimidine-5-boronic acid pinacol ester

Biochemical Assay Reagents

Pyrimidine-5-boronic acid pinacol ester is a derivative of Boronic acid. Boronic acid is an intermediate commonly used in organic synthesis reactions and can be used as a key reagent in the Suzuki-Miyaura reaction. It generates organic free radicals through oxygen-mediated oxidation and exhibits potential mutagenic activity. Boronic acid is mainly used in research in the fields of drug synthesis and catalytic reactions. Pyrimidine-5-boronic acid pinacol ester serves as a building block in DNA-compatible one-pot click chemistry for synthesis of DNA-encoded libraries .

HY-41832

4,6-Dichloro-2-(methylthio)pyrimidine	Biochemical Assay Reagents
4,6-Dichloro-2-(methylthio)pyrimidine is an intermediate. 4,6-Dichloro-2-(methylthio)pyrimidine can be used to synthesize Kras modulators. 4,6-Dichloro-2-(methylthio)pyrimidine can be used in cancer research .

HY-33638

(2-Chloropyrimidin-5-yl)methanol 2-chloro-5-pyrimidinemethanol; 2-chloro-5-(hydroxymethyl)pyrimidine	Biochemical Assay Reagents
(2-Chloropyrimidin-5-yl)methanol (2-Chloro-5-pyrimidinemethanol) is an inorganic catalyst .

HY-77336

*6-Chloro-7-iodo-7-deazapurine*	Biochemical Assay Reagents
4-Chloro-5-iodo-1H-pyrrolo[2,3-d]pyrimidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W002860

Cycloheptane-1,3-dione	Biochemical Assay Reagents
Cycloheptane-1,3-dione (Compound 1A) is an intermediate. Cycloheptane-1,3-dione can be used to synthesize Compound 1-1. Compound 1-1 has anticancer activity against colon cancer .

HY-78337

*Methyl pyrimidine-2-carboxylate*	Biochemical Assay Reagents
Methyl pyrimidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W001851

1-Benzylpyrrole-2,5-dione N-Benzylmaleimide	Biochemical Assay Reagents
1-Benzylpyrrole-2,5-dione (N-Benzylmaleimide) is a heterocyclic compound containing a maleimide ring and a benzyl group. 1-Benzylpyrrole-2,5-dione can be used as a key reactant for the green chemical modification of cellulose nanocrystals (CNC).

HY-W488088

Pyrimidine-4-carboxylic acid sodium	Biochemical Assay Reagents
Pyrimidine-4-carboxylic acid (sodium) is a kind of biochemical reagent.

Cat. No.	Product Name	Target	Research Area

HY-P10579

123B9 1 Publications Verification	Ephrin Receptor	Cancer
123B9, a tumor-homing agent, is a potent and selective EphA2 agonist with a K_d value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. 123B9 does not appreciably inhibit the ligand binding domains of the most closely related EphA3 and EphA4 receptors .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W018758

1-Phenylpropane-1,2-dione	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Ephedraceae Other Diseases Plants Disease Research Fields Ephedra sinica Stapf Source Classification	SARS-CoV
1-Phenylpropane-1,2-dione is a SARS-CoV-2 helicase binder. 1-Phenylpropane-1,2-dione can be isolated from the young stems of Ephedra sinica. 1-Phenylpropane-1,2-dione is commonly used as an edible flavoring and a basic raw material in synthetic chemistry. 1-Phenylpropane-1,2-dione can be applied to research related to COVID-19 .

HY-W062171

Cyclo-(Pro-Gly) Pyrrolopiperazine-2,5-dione	Structural Classification Natural Products other families Plants Source Classification	Drug Derivative
Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae . Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions .

HY-Y0519

*Pyrimidine*	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .

HY-W012944

2-Methylcyclopentane-1,3-dione	Panax ginseng C. A. Meyer Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Plants Disease Research Fields Araliaceae Source Classification	Biochemical Assay Reagents
2-Methylcyclopentane-1,3-dione is a synthon . 2-Methylcyclopentane-1,3-dione can be used for the synthesis of (±)-α-cuparenone .

HY-W006492

5a-Pregnane-3,20-dione 1 Publications Verification	Structural Classification Classification of Application Fields Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Steroids Source Classification Cancer	Endogenous Metabolite
5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

HY-113302

19-Hydroxyandrost-4-ene-3,17-dione	Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite
19-Hydroxyandrost-4-ene-3,17-dione is a substrate for Corticotropin-lipotropin and Cytochrome P450 19A1.

HY-N7885

(25R)-Spirost-4-ene-3,12-dione (-)-(25R)-Spirost-4-ene-3,12-dione	Structural Classification Polygonum chinense Linn. Polygonaceae Plants Steroids Source Classification	Others
(25R)-Spirost-4-ene-3,12-dione ((-)-(25R)-Spirost-4-ene-3,12-dione) is a natural product that has an inhibitory effect on neutrophil superoxide anion production and histamine release from mast cells .

HY-N1203

(5α)-Stigmastane-3,6-dione	Simaroubaceae Ailanthus altissima (Mill.) Swingle Classification of Application Fields Plants Disease Research Fields Inflammation/Immunology Steroids Source Classification	Bacterial
(5α)-Stigmastane-3,6-dione is a naturally occurring sterol that could be isolated from fruits of Ailanthus altissima Swingle. Antimicrobial Activity. .

HY-Y0519R

Pyrimidine (Standard)	Structural Classification Natural Products Microorganisms Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Pyrimidine (Standard) is the analytical standard of Pyrimidine. This product is intended for research and analytical applications. Pyrimidine is a nitrogen-containing heterocyclic compound and endogenous metabolite. Pyrimidine derivatives can be used in pancreatic cancer, triple-negative breast cancer, colon carcinoma and neuron research .

HY-N16513

Muurol-4-ene-3,8-dione	Structural Classification Pongamia pinnata (L.) Pierre Terpenoids Sesquiterpenes Plants Compositae Source Classification	Others
Muurol-4-ene-3,8-dione (Compound 2), a sesquiterpene, is one of the main hepatotoxic components in Eupatorium adenophorum. Muurol-4-ene-3,8-dione has an inhibitory effect on the growth of both the normal human hepatocyte cell L02 and the human hepatocellular carcinoma cell HepG2 with IC₅₀ values of 87.52 and 104.48 μM .

HY-W004464

2-(1-Piperazinyl)pyrimidine	Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
2-(1-Piperazinyl)pyrimidine is the major metabolite of Tandospirone (HY-14558) .

HY-W062171R

Cyclo-(Pro-Gly) (Standard) Pyrrolopiperazine-2,5-dione (Standard)	Structural Classification Natural Products other families Plants Source Classification	Reference Standards Others
Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae . Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions .

HY-W018758R

*1-Phenylpropane-1,2-dione* (Standard)**	Structural Classification Ketones, Aldehydes, Acids Ephedraceae Plants Ephedra sinica Stapf Source Classification	Reference Standards Others
1-Phenylpropane-1,2-dione, isolated from young Ephedra sinica Stapf (Ephedraceae), is biosynthetic precursors of the ephedrine alkaloids .

HY-W004464R

*2-(1-Piperazinyl)pyrimidine* (Standard)**	Alkaloids Other Alkaloids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
2-(1-Piperazinyl)pyrimidine (Standard) is the analytical standard of 2-(1-Piperazinyl)pyrimidine. This product is intended for research and analytical applications. 2-(1-Piperazinyl)pyrimidine is the major metabolite of Tandospirone (HY-14558) .

HY-N3147

Olean-12-ene-3,11-dione	Terpenoids Crossopetalum uragoga (Jacq.) Kuntze Celastraceae Plants Pentacyclic Triterpenoids Source Classification	Others
Olean-12-ene-3,11-dione is a natural product that can be isolated from Euonymus laxiflorus and Canarium zeylanicum. Olean-12-ene-3,11-dione has antiinflammatory activity .

HY-W006492R

*5a-Pregnane-3,20-dione* (Standard)**	Structural Classification Disease markers Nervous System Disorder Endogenous metabolite Steroids Source Classification	Reference Standards Endogenous Metabolite
5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

HY-N12163

Stigmast-5-ene-3,7-dione	Terpenoids Diterpenoids Plants Penianthus longifolius Miers Menispermaceae Source Classification	Others
Stigmast-5-ene-3,7-dione (Compound 10) is a compound isolated from the roots, leaves and twigs of Penianthus longifolius .

HY-N1221

Stigmast-4-en-3,6-dione	Malvaceae Structural Classification Hibiscus cannabinus L. Plants Steroids Source Classification	Others
Stigmast-4-en-3,6-dione is an anti-inflammatory and anti-allergic agent which can be extracted from Hibiscus cannabinus and Piper betle .

HY-N8981

Bisabola-2,10-diene-1,9-dione	Triterpenes Terpenoids Alpinia intermedia Gagnep. Plants Source Classification Zingiberaceae	Others
Bisabola-2,10-diene-1,9-dione is a Triterpenoids product that can be isolated from the leaves of Alpinia intermedia .

HY-N3811

ent-11β-Hydroxyatis-16-ene-3,14-dione	Infection Classification of Application Fields Euphorbia boetica Terpenoids Diterpenoids Euphorbiaceae Plants Disease Research Fields Source Classification	RSV
ent-11β-Hydroxyatis-16-ene-3,14-dione (compound 11) is a diterpenoid from the fresh roots of Euphorbia jolkinii. ent-11β-Hydroxyatis-16-ene-3,14-dione has anti-RSV activity .

HY-W012944R

*2-Methylcyclopentane-1,3-dione* (Standard)**	Panax ginseng C. A. Meyer Structural Classification Ketones, Aldehydes, Acids Plants Araliaceae Source Classification	Drug Intermediate Reference Standards
2-Methylcyclopentane-1,3-dione (Standard) is the analytical standard of 2-Methylcyclopentane-1,3-dione (HY-W012944). This product is intended for research and analytical applications. 2-Methylcyclopentane-1,3-dione is a key intermediate for the total synthesis of steroids .

HY-N9704

n-Tritriacontan-16,18-dione	Natural Products Myrtaceae Plants Eucalyptus globulus Labill. Source Classification	Others
n-Tritriacontan-16,18-dione is a natural product .

HY-W142206

Cyclopent-4-ene-1,3-dione	Structural Classification Ketones, Aldehydes, Acids Myrtaceae Plants Acca sellowiana (O. Berg) Burret Source Classification	Fungal
Cyclopent-4-ene-1,3-dione is a potent antifungal inhibitor of chitin synthesis. Cyclopent-4-ene-1,3-dione is potently antifungal against human pathogenic Candida species (IC₅₀ = 1-2 μM). Cyclopent-4-ene-1,3-dione is detected in feijoa cultivars with high antifungal bioactivity. Cyclopent-4-ene-1,3-dione can be used for the research of fungal infections .

HY-N15729

1-(2,4,5-Trimethoxyphenyl)propane-1,2-dione	Natural Products Acoraceae Plants Source Classification	Others
1-(2,4,5-Trimethoxyphenyl)propane-1,2-dione is an aromatic compound found in Acorus calamus. 1-(2,4,5-Trimethoxyphenyl)propane-1,2-dione is promising for research of plant allelopathy and weed control .

Tag:	His (2) Strep (1) Tag Free (1)
Source:	E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P701979

	kshB Protein, Mycobacterium tuberculosis hmp; 3-ketosteroid-9-alpha-monooxygenase; ferredoxin reductase component; 3-ketosteroid-9-alpha-hydroxylase; ferredoxin reductase component; KSH; Androsta-1; 4-diene-3; 17-dione 9-alpha-hydroxylase; Rieske-type oxygenase; RO	Others	E. coli
	The kshB protein significantly degrades cholesterol by catalyzing the introduction of the 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD), resulting in the 9OHADD intermediate. It is spontaneously converted to HSA through the cleavage of the B ring and aromatization of the A ring. kshB Protein, Mycobacterium tuberculosis is the recombinant kshB protein, expressed by E. coli , with tag free.

HY-P701980

	kshB Protein, Mycobacterium tuberculosis (His) hmp; 3-ketosteroid-9-alpha-monooxygenase; ferredoxin reductase component; 3-ketosteroid-9-alpha-hydroxylase; ferredoxin reductase component; KSH; Androsta-1; 4-diene-3; 17-dione 9-alpha-hydroxylase; Rieske-type oxygenase; RO	Others	E. coli
	The kshB protein significantly degrades cholesterol by catalyzing the introduction of the 9a-hydroxyl moiety into 1,4-androstadiene-3,17-dione (ADD), resulting in the 9OHADD intermediate. It is spontaneously converted to HSA through the cleavage of the B ring and aromatization of the A ring. kshB Protein, Mycobacterium tuberculosis (His) is the recombinant kshB protein, expressed by E. coli , with N-6*His labeled tag.

HY-P703426

	kshA Protein, Mycobacterium tuberculosis (His, Strep) 3-ketosteroid-9-alpha-monooxygenase, oxygenase component; 3-ketosteroid-9-alpha-hydroxylase, oxygenase component; KSH; Androsta-1,4-diene-3,17-dione 9-alpha-hydroxylase; 1.14.15.30; Rieske-type oxygenase; RO; kshA; Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); Oxidoreductase;	Others	E. coli
	kshA Protein, Mycobacterium tuberculosis (His, Strep) is the recombinant kshA, expressed by E. coli , with Strep, His labeled tag. ,

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-W006492S

*5a-Pregnane-3,20-dione-d6*
5a-Pregnane-3,20-dione-d₆ is the deuterium labeled 5a-Pregnane-3,20-dione. 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

HY-W777266

*Cyclohexane-1,3-dione-13C3*
Cyclohexane-1,3-dione- ¹³C₃ is the ¹³C-labeled Cyclohexane-1,3-dione (HY-W007466). Cyclohexane-1,3-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W777928

*Cyclohexane-1,3-dione-13C6*
Cyclohexane-1,3-dione- ¹³C₆ is the ¹³C-labeled Cyclohexane-1,3-dione (HY-W007466). Cyclohexane-1,3-dione is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W088589S

*(S)-3-Aminopiperidine-2,6-dione-d1 hydrochloride*
(S)-3-Aminopiperidine-2,6-dione-d hydrochloride is the deuterium labeled (S)-3-Aminopiperidine-2,6-dione hydrochloride .

HY-W088629S

*(R)-3-Aminopiperidine-2,6-dione-d1 hydrochloride*
(R)-3-Aminopiperidine-2,6-dione-d hydrochloride is the deuterium labeled (R)-3-Aminopiperidine-2,6-dione hydrochloride .

HY-W711213

1-(Methyl-d3)pyrrolidine-2,5-dione
1-(Methyl-d₃)pyrrolidine-2,5-dione is the deuterium labeled 1-Methylpyrrolidine-2,5-dione (HY-W098559).

HY-W251493S

5-Acetyl-d3-uracil
5-Acetyl-d₃-uracil (5-Acetyl-1H-pyrimidine-2,4-dione-d₃) is the deuterium labeled 3-Azidopropyl 4-methylbenzenesulfonate.

HY-W004464S

*2-(1-Piperazinyl)pyrimidine-d8*
2-(1-Piperazinyl)pyrimidine-d₈ is deuterium labeled 2-(1-Piperazinyl)pyrimidine.

HY-W711467

*1-Ethyl-3-hydroxypyrrolidine-2,5-dione-d5*
1-Ethyl-3-hydroxypyrrolidine-2,5-dione-d₅ is the deuterium labeled 1-Ethyl-3-hydroxypyrrolidine-2,5-dione (HY-W557068).

Cat. No.	Product Name		Classification

HY-152980

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine		Nucleoside Analogs
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152986

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine		Nucleoside Analogs
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152977

4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine		Nucleoside Analogs
4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-152818

4-Chloro-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine		Nucleoside Analogs
4-Chloro-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

7-chloro-8-fluoropyrido[4,3-d]pyrimidine-2,4(1H,3H)-dione

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Oligonucleotides

Natural
Products