Cyclohexane-1,3-dione
Based on 1 publication(s) in Google Scholar
Cyclohexane-1,3-dione is a drug intermediate, and its derivatives can exhibit significant tyrosine kinase inhibitory activity and anti-tumor activity.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 99.99%
- CAS No.: 504-02-9
- Formule: C6H8O2
- Masse moléculaire:112.13
-
Stockage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
-
Solvant et solubilité
- Pureté et documentation
- Références
-
Help & FAQs
-
HY-D0715
FluorescamineFluorescent Dye -
HY-W018778
2-Methyl-1,3-cyclohexanedioneDrug Intermediate -
HY-D0017
Dansyl chlorideFluorescent Dye -
HY-W012669
PhthalaldehydeGram-negative vegetative bacteria Inhibitor -
HY-D0715R
Fluorescamine (Standard)Standard of Fluorescamine -
HY-D0890
ABEIBiochemical Assay Reagent -
HY-D0036
Br-MmcFluorescent Label -
HY-W273413
4-Hydrazino-7-nitro-benzofurazan hydrazine adductFluorescent Reagent -
HY-D0102
4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazoleFluorescent Reagent -
HY-W269179
4-Bromomethyl-6,7-dimethoxycoumarinFluorescent Label -
HY-W012669R
Phthalaldehyde (Standard)Biochemical Assay Reagent -
HY-W012469
O-(4-Nitrobenzyl)hydroxylamine hydrochlorideBiochemical Assay Reagents
Publications Citing Use of MedChemExpress (MCE) Cyclohexane-1,3-dione
More
Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| LS180 | IC50 |
>100 μM
Compound: 128
|
Anticancer activity against human LS180 assessed as inhibition in cell viability
Anticancer activity against human LS180 assessed as inhibition in cell viability
|
[PMID: 33276991] |
| MCF7 | IC50 |
100 μM
Compound: 128
|
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 96 hrs by SRB assay
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 96 hrs by SRB assay
|
[PMID: 33276991] |
Chemical Information
-
CAS No. 504-02-9
-
Appearance Solid
-
Masse moléculaire 112.13
-
Formule C6H8O2
-
Color White to light yellow
-
SMILES
O=C1CC(CCC1)=O
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Autophagy
2026 Apr;22(4):763-778. PMID: 41697162
Solvant et solubilité
In Vitro:
DMSO : ≥ 100 mg/mL (891.82 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
-
Fiche technique (273 KB)
-
SDS (614 KB)
- English - EN (614 KB)
- Français - FR (614 KB)
- Deutsch - DE (614 KB)
- Norwegian - NO (614 KB)
- Español - ES (614 KB)
- Swedish - SV (614 KB)
- Italian - IT (614 KB)
- Korean - KR (614 KB)
- Portuguese - PT (614 KB)
-
Instruction de manipulation (2659 KB)
Références
[1]. Daoui O, et al. Cyclohexane-1,3-dione Derivatives as Future Therapeutic Agents for NSCLC: QSAR Modeling, In Silico ADME-Tox Properties, and Structure-Based Drug Designing Approach. ACS Omega. 2023 Jan 19;8(4):4294-4319. [Content Brief]
[2]. Megally Abdo NY, et al. Uses of cyclohexane-1,3-dione for the synthesis of 1,2,4-triazine derivatives as anti-proliferative agents and tyrosine kinases inhibitors. Bioorg Chem. 2020 Apr;97:103667. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.9182 mL | 44.5911 mL | 89.1822 mL | 222.9555 mL |
| 5 mM | 1.7836 mL | 8.9182 mL | 17.8364 mL | 44.5911 mL | |
| 10 mM | 0.8918 mL | 4.4591 mL | 8.9182 mL | 22.2956 mL | |
| 15 mM | 0.5945 mL | 2.9727 mL | 5.9455 mL | 14.8637 mL | |
| 20 mM | 0.4459 mL | 2.2296 mL | 4.4591 mL | 11.1478 mL | |
| 25 mM | 0.3567 mL | 1.7836 mL | 3.5673 mL | 8.9182 mL | |
| 30 mM | 0.2973 mL | 1.4864 mL | 2.9727 mL | 7.4319 mL | |
| 40 mM | 0.2230 mL | 1.1148 mL | 2.2296 mL | 5.5739 mL | |
| 50 mM | 0.1784 mL | 0.8918 mL | 1.7836 mL | 4.4591 mL | |
| 60 mM | 0.1486 mL | 0.7432 mL | 1.4864 mL | 3.7159 mL | |
| 80 mM | 0.1115 mL | 0.5574 mL | 1.1148 mL | 2.7869 mL | |
| 100 mM | 0.0892 mL | 0.4459 mL | 0.8918 mL | 2.2296 mL |
Cyclohexane-1,3-dione Related Classifications
HY-W007466 Related Classifications
Powered by Bioz