5,5'-Oxybis(isobenzofuran-1,3-dione)
Based on 1 Customer Validation
5,5'-Oxybis(isobenzofuran-1,3-dione) is a drug intermediate for synthesis of various active compounds.
For research use only. We do not sell to patients.
- Purity : 99.53%
- CAS No.: 1823-59-2
- Formula: C16H6O7
- Molecular Weight:310.22
-
Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | IC50 |
>200 μM
Compound: 11
|
Cytotoxicity against rat hepatocyte cells after 48 hrs by MTT assay
Cytotoxicity against rat hepatocyte cells after 48 hrs by MTT assay
|
[PMID: 20691337] |
| HepG2 | IC50 |
121 μM
Compound: 11
|
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 20691337] |
| SK-HEP1 | IC50 |
199 μM
Compound: 11
|
Cytotoxicity against human SKHEP1 cells after 48 hrs by MTT assay
Cytotoxicity against human SKHEP1 cells after 48 hrs by MTT assay
|
[PMID: 20691337] |
Chemical Information
-
CAS No. 1823-59-2
-
Appearance Solid
-
Molecular Weight 310.22
-
Formula C16H6O7
-
Color White to off-white
-
SMILES
O=C1OC(C2=C1C=CC(OC3=CC4=C(C(OC4=O)=O)C=C3)=C2)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 33.33 mg/mL (107.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (246 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2235 mL | 16.1176 mL | 32.2352 mL | 80.5880 mL |
| 5 mM | 0.6447 mL | 3.2235 mL | 6.4470 mL | 16.1176 mL | |
| 10 mM | 0.3224 mL | 1.6118 mL | 3.2235 mL | 8.0588 mL | |
| 15 mM | 0.2149 mL | 1.0745 mL | 2.1490 mL | 5.3725 mL | |
| 20 mM | 0.1612 mL | 0.8059 mL | 1.6118 mL | 4.0294 mL | |
| 25 mM | 0.1289 mL | 0.6447 mL | 1.2894 mL | 3.2235 mL | |
| 30 mM | 0.1075 mL | 0.5373 mL | 1.0745 mL | 2.6863 mL | |
| 40 mM | 0.0806 mL | 0.4029 mL | 0.8059 mL | 2.0147 mL | |
| 50 mM | 0.0645 mL | 0.3224 mL | 0.6447 mL | 1.6118 mL | |
| 60 mM | 0.0537 mL | 0.2686 mL | 0.5373 mL | 1.3431 mL | |
| 80 mM | 0.0403 mL | 0.2015 mL | 0.4029 mL | 1.0073 mL | |
| 100 mM | 0.0322 mL | 0.1612 mL | 0.3224 mL | 0.8059 mL |