1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 5a-Pregnane-3,20-dione


Cat. No.: HY-W006492 Purity: ≥98.0%
Handling Instructions

5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

For research use only. We do not sell to patients.

5a-Pregnane-3,20-dione Chemical Structure

5a-Pregnane-3,20-dione Chemical Structure

CAS No. : 566-65-4

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Free Sample (0.5-1 mg)   Apply Now  
500 mg USD 240 In-stock
Estimated Time of Arrival: December 31
1 g USD 350 In-stock
Estimated Time of Arrival: December 31
5 g USD 550 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.

IC50 & Target

Human Endogenous Metabolite


In Vitro

5a-Pregnane-3,20-dione decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerizes F-actin in MCF-7 breast cancer cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight





Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 3.33 mg/mL (10.52 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1598 mL 15.7988 mL 31.5976 mL
5 mM 0.6320 mL 3.1598 mL 6.3195 mL
10 mM 0.3160 mL 1.5799 mL 3.1598 mL
*Please refer to the solubility information to select the appropriate solvent.

Purity: ≥98.0%

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5a-Pregnane-3,20-dioneEndogenous MetaboliteInhibitorinhibitorinhibit

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