16α-Hydroxyestrone
Based on 3 publication(s) in Google Scholar
16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite. 16α-Hydroxyestrone (16αOHE) can be used for the research of metabolic disease.
For research use only. We do not sell to patients.
- Purity: 99.74%
- CAS No.: 566-76-7
- Formula: C18H22O3
- Molecular Weight:286.37
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) 16α-Hydroxyestrone
MoreAll Endogenous Metabolite Isoforms
More
Biological Activity
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Human Endogenous Metabolite |
Increasing levels of active estrogen metabolites, 16α-Hydroxyestrone and E3, are associated with increasing bone mineral densit[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 566-76-7
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Appearance Solid
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Molecular Weight 286.37
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Formula C18H22O3
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Color White to off-white
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SMILES
C[C@]1([C@](C[C@H]2O)([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])CC1)C2=O
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Synonyms
16αOHE
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (3)
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Journal Impact Factor
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Most Recent
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Cell Metab
Sensing steroid hormone 17α-hydroxypregnenolone by GPR56 enables protection from ferroptosis-induced liver injury. [Abstract]2024 Nov 5;36(11):2402-2418.e10. PMID: 39389061 -
Proc Natl Acad Sci U S A
2022 Apr 12;119(15):e2117004119. PMID: 35394864 -
Anal Chem
Online Charge-Generation Derivatization by Electrochemical Radical Cations of Thianthrene: Mass Spectrometry Imaging of Estrogens in Biological Tissues. [Abstract]2024 Jul 20. PMID: 39031066
Solvent & Solubility
DMSO : ≥ 250 mg/mL (873.00 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4920 mL | 17.4599 mL | 34.9199 mL | 87.2996 mL |
| 5 mM | 0.6984 mL | 3.4920 mL | 6.9840 mL | 17.4599 mL | |
| 10 mM | 0.3492 mL | 1.7460 mL | 3.4920 mL | 8.7300 mL | |
| 15 mM | 0.2328 mL | 1.1640 mL | 2.3280 mL | 5.8200 mL | |
| 20 mM | 0.1746 mL | 0.8730 mL | 1.7460 mL | 4.3650 mL | |
| 25 mM | 0.1397 mL | 0.6984 mL | 1.3968 mL | 3.4920 mL | |
| 30 mM | 0.1164 mL | 0.5820 mL | 1.1640 mL | 2.9100 mL | |
| 40 mM | 0.0873 mL | 0.4365 mL | 0.8730 mL | 2.1825 mL | |
| 50 mM | 0.0698 mL | 0.3492 mL | 0.6984 mL | 1.7460 mL | |
| 60 mM | 0.0582 mL | 0.2910 mL | 0.5820 mL | 1.4550 mL | |
| 80 mM | 0.0436 mL | 0.2182 mL | 0.4365 mL | 1.0912 mL | |
| 100 mM | 0.0349 mL | 0.1746 mL | 0.3492 mL | 0.8730 mL |
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