6,7-Dibromoquinoline-5,8-dione
Based on 1 Customer Validation
6,7-Dibromoquinoline-5,8-dione is a drug intermediate for synthesis of various active compounds.
For research use only. We do not sell to patients.
- Purity : 95.48%
- CAS No.: 18633-05-1
- Formula: C9H3Br2NO2
- Molecular Weight:316.94
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
21.5 μM
Compound: 5
|
Cytotoxicity against human HeLa cells after 6 days by WST1 colorimetric assay
Cytotoxicity against human HeLa cells after 6 days by WST1 colorimetric assay
|
[PMID: 18789703] |
| HeLa | IC50 |
4.1 μM
Compound: 5
|
Antiproliferative activity against human HeLa cells after 10 days by clonogenic assay
Antiproliferative activity against human HeLa cells after 10 days by clonogenic assay
|
[PMID: 18789703] |
Chemical Information
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CAS No. 18633-05-1
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Appearance Solid
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Molecular Weight 316.94
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Formula C9H3Br2NO2
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SMILES
O=C(C(Br)=C1Br)C2=C(N=CC=C2)C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 3.33 mg/mL (10.51 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (246 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1552 mL | 15.7759 mL | 31.5517 mL | 78.8793 mL |
| 5 mM | 0.6310 mL | 3.1552 mL | 6.3103 mL | 15.7759 mL | |
| 10 mM | 0.3155 mL | 1.5776 mL | 3.1552 mL | 7.8879 mL |