Cyclo-(Pro-Gly) (Synonyms: Pyrrolopiperazine-2,5-dione)

Name: Cyclo-(Pro-Gly)
Brand: MedChemExpress
SKU: HY-W062171
Rating: 4.5 (1 reviews)

Cat. No.: HY-W062171 Purity: 95.22%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae. Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions.

For research use only. We do not sell to patients.

Cyclo-(Pro-Gly) Chemical Structure

CAS No. : 19179-12-5

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in DMSO ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 55	In-stock	Estimated Time of Arrival: December 31
Solid
50 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae^[1]. Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions^[2].

In Vivo

Cyclo-(Pro-Gly) (0.1 and 10 mg/kg, ip ) seems to be a memory facilitating substance and its presence in rat brain suggests the existence of a new mechanism of memory regulation^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

154.17

Formula

C₇H₁₀N₂O₂

CAS No.

19179-12-5

Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1)C(CCC2)N2C1=O

Structure Classification

Others

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (648.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.4863 mL	32.4317 mL	64.8635 mL
5 mM	1.2973 mL	6.4863 mL	12.9727 mL
10 mM	0.6486 mL	3.2432 mL	6.4863 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.22%

Select Batch:

Data Sheet (274 KB) SDS (393 KB)

COA (250 KB) HNMR (132 KB) RP-HPLC (276 KB)

Handling Instructions (2659 KB)

References

[1]. Ying-ying Sun, et al. Isolation, Purification, and Identification of Antialgal Substances in Green Alga Ulva Prolifera for Antialgal Activity Against the Common Harmful Red Tide Microalgae. Environ Sci Pollut Res Int. 2016 Jan;23(2):1449-59. [Content Brief]

[2]. Fumitaka Hayasaka, et al. Production Method for Cyclic Dipeptide Derived from Native Collagen. Food Science and Technology Research, 22 (4), 477-483, 2016.

[3]. T A Gudasheva, et al. Identification of a Novel Endogenous Memory Facilitating Cyclic Dipeptide Cyclo-Prolylglycine in Rat Brain. FEBS Lett. 1996 Aug 5;391(1-2):149-52. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.4863 mL	32.4317 mL	64.8635 mL	162.1587 mL
	5 mM	1.2973 mL	6.4863 mL	12.9727 mL	32.4317 mL
	10 mM	0.6486 mL	3.2432 mL	6.4863 mL	16.2159 mL
	15 mM	0.4324 mL	2.1621 mL	4.3242 mL	10.8106 mL
	20 mM	0.3243 mL	1.6216 mL	3.2432 mL	8.1079 mL
	25 mM	0.2595 mL	1.2973 mL	2.5945 mL	6.4863 mL
	30 mM	0.2162 mL	1.0811 mL	2.1621 mL	5.4053 mL
	40 mM	0.1622 mL	0.8108 mL	1.6216 mL	4.0540 mL
	50 mM	0.1297 mL	0.6486 mL	1.2973 mL	3.2432 mL
	60 mM	0.1081 mL	0.5405 mL	1.0811 mL	2.7026 mL
	80 mM	0.0811 mL	0.4054 mL	0.8108 mL	2.0270 mL
	100 mM	0.0649 mL	0.3243 mL	0.6486 mL	1.6216 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclo-(Pro-Gly)19179-12-5Pyrrolopiperazine-2,5-dioneOthersInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks

Product Name			Lot #
Applicant Name *			Email Address *
Phone Number			Department *
Organization Name *			Country or Region *
Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

Cyclo-(Pro-Gly) (Synonyms: Pyrrolopiperazine-2,5-dione)

Customer Review

Cyclo-(Pro-Gly) Related Antibodies

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

Keywords:

Your Recently Viewed Products:

Customer Review

Request for HNMR Report

Request for HNMR Report