Pyrimidine-5-boronic acid pinacol ester
Based on 1 Customer Validation
Pyrimidine-5-boronic acid pinacol ester is a derivative of Boronic acid. Boronic acid is an intermediate commonly used in organic synthesis reactions and can be used as a key reagent in the Suzuki-Miyaura reaction. It generates organic free radicals through oxygen-mediated oxidation and exhibits potential mutagenic activity. Boronic acid is mainly used in research in the fields of drug synthesis and catalytic reactions. Pyrimidine-5-boronic acid pinacol ester serves as a building block in DNA-compatible one-pot click chemistry for synthesis of DNA-encoded libraries.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 321724-19-0
- Formula: C10H15BN2O2
- Molecular Weight:206.05
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-I0308
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1-Boc-pyrazole-4-boronic acid pinacol ester
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HY-40249
1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester
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HY-W008147
3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
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HY-59226
5-Pyrimidylboronic acid
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HY-W012386
2-Fluoropyridine-5-boronic acid pinacol ester
Biological Activity
Pyrimidine-5-boronic acid pinacol ester (400 mM; 4 h) undergoes a DNA-compatible one-pot click reaction with DNA-conjugated terminal alkyne to form a DNA-conjugated 1,2,3-triazole[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 321724-19-0
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Appearance Solid
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Molecular Weight 206.05
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Formula C10H15BN2O2
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Color White to off-white
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SMILES
CC1(C)OB(C2=CN=CN=C2)OC1(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (485.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8532 mL | 24.2660 mL | 48.5319 mL | 121.3298 mL |
| 5 mM | 0.9706 mL | 4.8532 mL | 9.7064 mL | 24.2660 mL | |
| 10 mM | 0.4853 mL | 2.4266 mL | 4.8532 mL | 12.1330 mL | |
| 15 mM | 0.3235 mL | 1.6177 mL | 3.2355 mL | 8.0887 mL | |
| 20 mM | 0.2427 mL | 1.2133 mL | 2.4266 mL | 6.0665 mL | |
| 25 mM | 0.1941 mL | 0.9706 mL | 1.9413 mL | 4.8532 mL | |
| 30 mM | 0.1618 mL | 0.8089 mL | 1.6177 mL | 4.0443 mL | |
| 40 mM | 0.1213 mL | 0.6066 mL | 1.2133 mL | 3.0332 mL | |
| 50 mM | 0.0971 mL | 0.4853 mL | 0.9706 mL | 2.4266 mL | |
| 60 mM | 0.0809 mL | 0.4044 mL | 0.8089 mL | 2.0222 mL | |
| 80 mM | 0.0607 mL | 0.3033 mL | 0.6066 mL | 1.5166 mL | |
| 100 mM | 0.0485 mL | 0.2427 mL | 0.4853 mL | 1.2133 mL |
Pyrimidine-5-boronic acid pinacol ester Related Classifications
HY-42045 Related Classifications
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