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2-benzofuran-2-yl-2-imidazoline-d4-hydrochloride

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (4) Adrenergic Receptor (26) Angiotensin Receptor (2) Apoptosis (2) Autophagy (2) Bacterial (2) Biochemical Assay Reagents (4) Calcium Channel (1) Calmodulin (1) Caspase (2) CRFR (1) Dopamine Receptor (1) Drug Derivative (16) Drug Intermediate (8) Drug Isomer (2) Drug Metabolite (3) Endogenous Metabolite (2) FKBP (1) Fluorescent Dye (1) Fungal (1) Histamine Receptor (1) HIV (1) Imidazoline Receptor (27) Insulin Receptor (1) Isotope-Labeled Compounds (6) Lactate Dehydrogenase (2) LDLR (8) Mitochondrial Metabolism (2) MOFs (1) Monoamine Oxidase (2) NO Synthase (1) Parasite (1) PCSK9 (1) Potassium Channel (1) PROTACs (1) Reactive Oxygen Species (ROS) (1) Reference Standards (12) SARS-CoV (1) Serotonin Transporter (1) TNF Receptor (2) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (15) Cardiovascular Disease (26) Endocrinology (6) Infection (9) Inflammation/Immunology (4) Metabolic Disease (9) Neurological Disease (40)

By Targets:

5-HT Receptor (4)

Adrenergic Receptor (26)

Angiotensin Receptor (2)

Apoptosis (2)

Autophagy (2)

Bacterial (2)

Biochemical Assay Reagents (4)

Calcium Channel (1)

Calmodulin (1)

Caspase (2)

CRFR (1)

Dopamine Receptor (1)

Drug Derivative (16)

Drug Intermediate (8)

Drug Isomer (2)

Drug Metabolite (3)

Endogenous Metabolite (2)

FKBP (1)

Fluorescent Dye (1)

Fungal (1)

Histamine Receptor (1)

HIV (1)

Imidazoline Receptor (27)

Insulin Receptor (1)

Isotope-Labeled Compounds (6)

Lactate Dehydrogenase (2)

LDLR (8)

Mitochondrial Metabolism (2)

MOFs (1)

Monoamine Oxidase (2)

NO Synthase (1)

Parasite (1)

PCSK9 (1)

Potassium Channel (1)

PROTACs (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (12)

SARS-CoV (1)

Serotonin Transporter (1)

TNF Receptor (2)

Toll-like Receptor (TLR) (1)

By Research Areas:

Cancer (15)

Cardiovascular Disease (26)

Endocrinology (6)

Infection (9)

Inflammation/Immunology (4)

Metabolic Disease (9)

Neurological Disease (40)

100

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14188

Amiodarone hydrochloride Maximum Cited Publications 12 Publications Verification	Potassium Channel Autophagy	Cardiovascular Disease Infection Neurological Disease Cancer
Amiodarone hydrochloride, a benzofuran-based Class III antiarrhythmic agent, inhibits WT outward ionic current (IhERG) tails with an IC₅₀ of ∼45 nM . Amiodarone hydrochloride induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling in fibroblasts . Amiodarone hydrochloride can be used in the research of both supraventricular and ventricular arrhythmias .

HY-145514C

dTAGV-1 hydrochloride 5 Publications Verification	FKBP PROTACs	Cancer
dTAGV-1 hydrochloride is a potent and selective degrader of FKBP12 ^F36V-tagged proteins PROTAC degrader. dTAGV-1 hydrochloride can induce degradation of FKBP12 ^F36V-Nluc in vivo. (Pink: Target Protein Ligand (HY-114420); Black: Linker (HY-W012001); Blue: VHL Ligand (HY-112078); VHL Ligan+Linker (HY-173628A)) .

HY-101374A

AGN 192403 hydrochloride (+)-BRD4780	Imidazoline Receptor Caspase Mitochondrial Metabolism Lactate Dehydrogenase	Cardiovascular Disease Neurological Disease Cancer
AGN 192403 (BRD4780) hydrochloride is a potent and selective imidazoline-1 receptor antagonist with a K_i value of 42 nM. AGN 192403 hydrochloride is also a TMED9 inhibitor. AGN 192403 hydrochloride shows protective effects on oxidative cytotoxicity and mitochondrial inhibitor-induced cytotoxicity in astrocytes. AGN 192403 hydrochloride mitigates the proliferation and migration of differentiated glioma tumor cells. AGN 192403 hydrochloride can be used for glioma tumor and neurological diseases research .

HY-103697

Gardiquimod	Toll-like Receptor (TLR)	Cancer
Gardiquimod is an imidazoline TLR7/8 agonist. Gardiquimod inhibits HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod specifically activates TLR7 at concentrations below 10 μM.

HY-101238

Agmatine sulfate 1 Publications Verification	Imidazoline Receptor NO Synthase Endogenous Metabolite	Neurological Disease Cancer
Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor.

HY-W004842

Benzofuran-2-carboxaldehyde	Fungal	Others
Benzofuran-2-carboxaldehyde is a benzofuran derivative with a bitter almond odor. Benzofuran-2-carboxaldehyde exhibits high antifungal activity .

HY-B1052

Lofexidine hydrochloride Baq-168; MDL-14042	Adrenergic Receptor Imidazoline Receptor	Neurological Disease Metabolic Disease
Lofexidine hydrochloride (Baq-168) is an orally active agonist of the imidazoline I1 receptor (imidazoline I1 receptor) (Ki: 1.9 nM) and α₂-adrenergic receptor (α2-adrenergic receptor). Lofexidine hydrochloride binds to the α₂A-adrenergic receptor, reduces sympathetic outflow, lowers blood pressure, and exhibits vasoconstrictive effects. Lofexidine hydrochloride regulates the expression of c-fos and alleviates opioid withdrawal symptoms. Lofexidine hydrochloride is applicable to research on opioid addiction and withdrawal .

HY-14561A

Idazoxan hydrochloride RX 781094 hydrochloride	Adrenergic Receptor Imidazoline Receptor	Neurological Disease Endocrinology
Idazoxan hydrochloride (RX 781094 hydrochloride) is an α₂-adrenoceptor antagonist and is also a imidazoline receptors (IRs) antagonist competitively antagonized the centrally induced hypotensive effect of imidazoline-like agents (IMs). Idazoxan hydrochloride also improves motor symptoms in Parkinson’s disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism .

HY-B0374

Moxonidine BDF5895	Imidazoline Receptor Adrenergic Receptor LDLR	Cardiovascular Disease Neurological Disease
Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I₁-R) agonist. Moxonidine activates imidazoline I₁ receptors and α₂ adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis .

HY-B0556A

Tetrahydrozoline hydrochloride Tetryzoline hydrochloride	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .

HY-N15642

Farfugin A	Drug Derivative	Others
Farfugin A (Compound 2) is a benzofuran derivative .

HY-B0374A

Moxonidine hydrochloride BDF5895 hydrochloride	Imidazoline Receptor Adrenergic Receptor LDLR	Cardiovascular Disease Neurological Disease
Moxonidine (BDF5895) hydrochloride is an orally active imidazoline type 1 receptor (I₁-R) agonist. Moxonidine hydrochloride activates imidazoline I₁ receptors and α₂ adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine hydrochloride reduces atherosclerotic lesions and lowers blood pressure. Moxonidine hydrochloride can be used in the study of hypertension, heart failure, and atherosclerosis .

HY-B1416A

Efaroxan hydrochloride	Adrenergic Receptor Imidazoline Receptor	Cardiovascular Disease Metabolic Disease
Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan hydrochloride is a selective *I1-Imidazoline* receptor** antagonist. Efaroxan hydrochloride can be used for the research of cardiovascular disease .

HY-W001165

3-Coumaranone benzofuran-3-one	Biochemical Assay Reagents	Others
3-Coumaranone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-B1052A

Lofexidine Baq-168 free base; MDL-14042 free base	Imidazoline Receptor Adrenergic Receptor	Neurological Disease Metabolic Disease
Lofexidine (Baq-168 free base) is an orally active agonist of the imidazoline I1 receptor (imidazoline I1 receptor) (Ki: 1.9 nM) and α₂-adrenergic receptor (α2-adrenergic receptor). Lofexidine binds to the α₂A-adrenergic receptor, reduces sympathetic outflow, lowers blood pressure, and exhibits vasoconstrictive effects. Lofexidine regulates the expression of c-fos and alleviates opioid withdrawal symptoms. Lofexidine is applicable to research on opioid addiction and withdrawal .

HY-W004801

Benzofuran-3-carbaldehyde	Drug Intermediate	Others
Benzofuran-3-carbaldehyde is a bioactive chemical, and can be used for the synthesis of active compound .

HY-141714

SBC-115337	PCSK9	Cardiovascular Disease Cancer
SBC-115337, as a potent benzofuran compound, is a PCSK9 inhibitor with an IC₅₀ value of 0.5 μM .

HY-D1760

*Sodium-binding benzofuran* isophthalate**	Fluorescent Dye	Others
SBFI is a cell-impermeant, fluorescent Na ⁺ indicator dye. SBFI is excited at 340 nm and the fluorophore emission is collected at 450 nm . SBFI selective for Na ⁺ over K ⁺ with K_d values of 20 and 120 mM for these ions, respectively. .

HY-B1800

Tolonidine	Angiotensin Receptor	Cardiovascular Disease
Tolonidine is a derivative of imidazoline. Tolonidine is orally active and has been shown to possess hypotensive and antihypertensive properties .

HY-101170

BU224 hydrochloride	Imidazoline Receptor Apoptosis TNF Receptor	Neurological Disease Inflammation/Immunology
BU224 hydrochloride is a selective and high affinity imidazoline I₂ receptor ligand, with a K_i of 2.1 nM. BU224 hydrochloride is sometimes used as an I₂ receptor antagonist. BU224 hydrochloride exerts neuroprotective effects, with anti-inflammatory and anti-apoptotic properties. BU224 hydrochloride improves memory in 5XFAD mice, enlarging dendritic spines and reducing Aβ-induced changes in NMDARs. BU224 hydrochloride can be used for Alzheimer's disease research .

HY-W004116

2-Benzofurylboronic acid	Biochemical Assay Reagents	Others
Benzofuran-2-boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-N4161

Euparin	Reactive Oxygen Species (ROS)	Infection Neurological Disease
Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects .

HY-15481

KU14R	Insulin Receptor	Metabolic Disease Endocrinology
KU14R is a new I(3)-R antagonist, which selectively blocks the insulin secretory response to imidazolines.

HY-N7503

Psoralenoside	Drug Intermediate Bacterial	Infection Cancer
Psoralenoside is an orally active benzofuran glycoside. Psoralenoside is isolated from the fruits of Psoralea corylifolia. As a metabolite precursor, Psoralenoside undergoes deglycosylation by intestinal flora to form Psoralen (HY-N0053). Psoralenoside is applicable to research related to cancer and bacterial infections .

HY-I0056

*Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate hydrochloride*	Drug Intermediate	Others
Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate hydrochloride is a drug intermediate for synthesis of various active compounds.

HY-77058A

5-(1-Piperazinyl)-2-benzofurancarboxylic acid ethyl ester dihydrochloride hydrate Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate dihydrochloride monohydrate	Drug Intermediate	Others
5-(1-Piperazinyl)-2-benzofurancarboxylic acid ethyl ester (Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate) dihydrochloride hydrate is a drug intermediate for synthesis of various active compounds.

HY-101374

AGN 192403 (+)-BRD4780 free base	Imidazoline Receptor Mitochondrial Metabolism Caspase Lactate Dehydrogenase	Cardiovascular Disease Neurological Disease Cancer
AGN 192403 (BRD4780) is a potent and selective imidazoline-1 receptor antagonist with a K_i value of 42 nM. AGN 192403 is also a TMED9 inhibitor. AGN 192403 shows protective effects on oxidative cytotoxicity and mitochondrial inhibitor-induced cytotoxicity in astrocytes. AGN 192403 mitigates the proliferation and migration of differentiated glioma tumor cells. AGN 192403 can be used for glioma tumor and neurological diseases research .

HY-W721302

2-APB hydrochloride	Monoamine Oxidase	Neurological Disease
2-APB is an analog of 6-APB, a benzofuran derivative and a psychoactive substance. Certain benzofuran derivatives have monoamine oxidase-A inhibitory activity .

HY-101100

Anpirtoline hydrochloride D-16949 hydrochloride	5-HT Receptor	Neurological Disease
Anpirtoline (D-16949) hydrochloride is a centrally acting 5-HT_1B receptor agonist, with K_is of 28 nM (5-HT_1B), 150 nM (5-HT_1A) and 1.49 μM (5-HT2). Anpirtoline hydrochloride has serotonergic, antinociceptive, antidepressant-like effects .

HY-W111370

2-Nitroamino-2-imidazoline	Parasite Drug Intermediate	Infection
2-Nitroamino-2-imidazoline is an intermediate in the synthesis of the neonicotinoid insecticide Imidacloprid (HY-B0838) .

HY-B0556

Tetrahydrozoline Tetryzoline	Adrenergic Receptor	Cardiovascular Disease
Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .

HY-N7504

Isopsoralenoside	Bacterial	Infection Metabolic Disease Cancer
Isopsoralenoside is a benzofuran glycoside from Psoralea corylifolia. Isopsoralenoside can be quickly metabolized to Psoralen (HY-N0053) in digestive tract contents. Isopsoralenoside show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .

HY-B0556AS

Tetrahydrozoline-d4 hydrochloride Tetryzoline-d4 hydrochloride	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease Endocrinology
Tetrahydrozoline-d₄ (hydrochloride) is the deuterium labeled Tetrahydrozoline hydrochloride. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .

HY-138813

N-Desethyl Sunitinib hydrochloride 5+ Cited Publications SU-12662 hydrochloride	Drug Metabolite	Cancer
N-Desethyl Sunitinib (SU-12662) (hydrochloride) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with K_i values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively .

HY-N1777

3,4-Dimethoxybenzamide	Drug Intermediate	Others
3,4-Dimethoxybenzamide, amide, is isolated from the solid culture of Streptoverticillium morookaense. 3,4-Dimethoxybenzamide can be used as the starting material to preparation Itopride hydrochloride .

HY-103376

NBI-27914 hydrochloride	CRFR	Neurological Disease
NBI-27914 (hydrochloride) is a selective Corticotropin-Releasing Factor 1 (CRF1) receptor antagonist with a K_i value of 1.7 nM .

HY-B0374S

Moxonidine-d4	Isotope-Labeled Compounds Imidazoline Receptor Adrenergic Receptor LDLR	Cardiovascular Disease Neurological Disease
Moxonidine-d₄ (BDF5895-d₄) is the deuterium labeled Moxonidine (HY-B0374). Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I₁-R) agonist. Moxonidine activates imidazoline I₁ receptors and α₂ adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis .

HY-W1121922

(±)-Mintlactone	Drug Derivative	Neurological Disease
(±)-Mintlactone is a member of benzofurans that can be found in the essential oil of Menthu piperitu L. (peppermint oil) .

HY-N1352

Rhuscholide A	HIV	Infection
Rhuscholide A is a benzofuran lactone that shows significant anti-HIV-1 activity, with an EC₅₀ of 1.62 μM .

HY-N8750

5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran	Others	Others
5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran serves as a phytoalexin.

HY-N7724

Cedrusin (+)-Cedrusin	Others	Others
Cedrusin is a benzofuran derivative that can be isolated from Styrax suberifolius .

HY-105167A

E 047/1 E 0471	Others	Cardiovascular Disease
MW-436 (E 0471) hydrochloride is a benzofuran compound with antiarrhythmic effects. MW-436 hydrochloride can be used for the research of cardiovascular disease .

HY-N15520

Moracin J	Others	Others
Moracin J is found in the leaves of Cassia fistula. Moracin J is a derivative of the benzofuran compound Moracin .

HY-B1416AR

Efaroxan hydrochloride (Standard)	Adrenergic Receptor Imidazoline Receptor	Cardiovascular Disease Metabolic Disease
Efaroxan (hydrochloride) (Standard) is the analytical standard of Efaroxan (hydrochloride). This product is intended for research and analytical applications. Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan hydrochloride is a selective I1-Imidazoline receptor antagonist. Efaroxan hydrochloride can be used for the research of cardiovascular disease .

HY-B1800R

Tolonidine (Standard)	Angiotensin Receptor Reference Standards	Cardiovascular Disease
Tolonidine (Standard) is the analytical standard of Tolonidine. This product is intended for research and analytical applications. Tolonidine is a derivative of imidazoline. Tolonidine is orally active and has been shown to possess hypotensive and antihypertensive properties .

HY-106207

Celivarone SSR149744C	Drug Derivative	Cardiovascular Disease
Celivarone (SSR149744C) is a orally active noniodinated benzofuran derivative with antiarrhythmic properties. Celivarone has the potential for atrial fibrillation and in ventricular arrhythmias research .

HY-W348072

SARS-CoV-2-IN-59	SARS-CoV	Infection
SARS-CoV-2-IN-59 (compound E07), an imidazoline derivative, is a non-peptide small molecule inhibitor of SARS-CoV-2 that targets the main protease (Mpro) of the coronavirus. SARS-CoV-2-IN-59 has a strong interaction with residues on Mpro (Met 165, Gln 166, Met 165, His 41, Gln 189) .

HY-N7503R

Psoralenoside (Standard)	Reference Standards Histamine Receptor Calcium Channel Calmodulin	Infection Metabolic Disease Cancer
Psoralenoside is a benzofuran glycoside from Psoralea corylifolia . Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol) . Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .

HY-101170R

BU224 hydrochloride (Standard)	Reference Standards Imidazoline Receptor Apoptosis TNF Receptor	Neurological Disease Inflammation/Immunology
BU224 (hydrochloride) (Standard) is the analytical standard of BU224 (hydrochloride). This product is intended for research and analytical applications. BU224 hydrochloride is a selective and high affinity imidazoline I2 receptor ligand, with a Ki of 2.1 nM. BU224 hydrochloride is sometimes used as an I2 receptor antagonist. BU224 hydrochloride exerts neuroprotective effects, with anti-inflammatory and anti-apoptotic properties. BU224 hydrochloride improves memory in 5XFAD mice, enlarging dendritic spines and reducing Aβ-induced changes in NMDARs. BU224 hydrochloride can be used for Alzheimer's disease research .

HY-129864A

4-APDB hydrochloride	Drug Derivative	Neurological Disease
4-APDB hydrochloride is a benzofuran.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-101238

Agmatine sulfate 1 Publications Verification	Natural Products Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Imidazoline Receptor NO Synthase Endogenous Metabolite
Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor.

HY-N15642

Farfugin A	Structural Classification Terpenoids Ligularia japonica (Thunb.) Less. Sesquiterpenes Asteraceae Plants Source Classification	Drug Derivative
Farfugin A (Compound 2) is a benzofuran derivative .

HY-N4161

Euparin	Monophenols Phenols Plants Compositae Guilandina minax (Hance) G. P. Lewis Source Classification	Reactive Oxygen Species (ROS)
Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects .

HY-N7503

Psoralenoside	Infection Structural Classification Classification of Application Fields Simple Phenylpropanols Leguminosae Metabolic Disease Phenylpropanoids Psoralea corylifolia L. Plants Disease Research Fields Source Classification	Drug Intermediate Bacterial
Psoralenoside is an orally active benzofuran glycoside. Psoralenoside is isolated from the fruits of Psoralea corylifolia. As a metabolite precursor, Psoralenoside undergoes deglycosylation by intestinal flora to form Psoralen (HY-N0053). Psoralenoside is applicable to research related to cancer and bacterial infections .

HY-N7504

Isopsoralenoside	Infection Classification of Application Fields Leguminosae Ketones, Aldehydes, Acids Metabolic Disease Psoralea corylifolia L. Plants Disease Research Fields Source Classification	Bacterial
Isopsoralenoside is a benzofuran glycoside from Psoralea corylifolia. Isopsoralenoside can be quickly metabolized to Psoralen (HY-N0053) in digestive tract contents. Isopsoralenoside show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .

HY-N1777

3,4-Dimethoxybenzamide	Natural Products Microorganisms Classification of Application Fields Other Diseases Disease Research Fields Source Classification	Drug Intermediate
3,4-Dimethoxybenzamide, amide, is isolated from the solid culture of Streptoverticillium morookaense. 3,4-Dimethoxybenzamide can be used as the starting material to preparation Itopride hydrochloride .

HY-W1121922

(±)-Mintlactone	Structural Classification Natural Products Crossostephium chinense (L.) Makino Labiatae Silene conoidea L. Plants Caryophyllaceae Source Classification	Drug Derivative
(±)-Mintlactone is a member of benzofurans that can be found in the essential oil of Menthu piperitu L. (peppermint oil) .

HY-N1352

Rhuscholide A	Natural Products Monophenols Rhus chinensis Mill. Phenols Plants Anacardiaceae Source Classification	HIV
Rhuscholide A is a benzofuran lactone that shows significant anti-HIV-1 activity, with an EC₅₀ of 1.62 μM .

HY-N8750

5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran	Natural Products Millettia peguensis Ali Plants Compositae Source Classification	Others
5-Acetyl-2-(1-hydroxy-1-methylethyl)benzofuran serves as a phytoalexin.

HY-N7724

Cedrusin (+)-Cedrusin	Styrax suberifolius Hook. et Arn. Styracaceae Plants Source Classification	Others
Cedrusin is a benzofuran derivative that can be isolated from Styrax suberifolius .

HY-N15520

Moracin J	Cassia fistula L. Leguminosae Cassia Phenols Polyphenols Plants Source Classification	Others
Moracin J is found in the leaves of Cassia fistula. Moracin J is a derivative of the benzofuran compound Moracin .

HY-N7503R

Psoralenoside (Standard)	Structural Classification Simple Phenylpropanols Leguminosae Phenylpropanoids Psoralea corylifolia L. Plants Source Classification	Reference Standards Histamine Receptor Calcium Channel Calmodulin
Psoralenoside is a benzofuran glycoside from Psoralea corylifolia . Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol) . Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity .

HY-N3805

Encecalin	Iridoids Terpenoids Anthyllis vulneraria L. Plants Compositae Source Classification	Others
Encecalin is a natural benzofuran compound .

HY-N2827

Aglain C (-)-Aglain C	Natural Products Aglaia argentea Blume Plants Meliaceae Source Classification	Others
Aglain C is isolated from A. ponapensis. Aglain C enhances the NF-kB inhibitory activity .

HY-N9910

Visamminol	Ketones, Aldehydes, Acids Artemisia cana Pursh Umbelliferae Plants Source Classification	Endogenous Metabolite
Visamminol is a spasmolytic which can be extracted from Cimicifuga dahurica. Visamminol exhibits a spasmolytic action that is one-third as potent as that of papaverine hydrochloride .

HY-N12991

Picraquassioside B	Simaroubaceae Plants Saccharides Picrasma quassioides(D．Don)Benn． Monosaccharides Source Classification	Others
Picraquassioside B is a benzofuran glucosides and can isolated from Cnidium monnieri fruits .

HY-N9224

5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran	Monophenols Phenols Plants Compositae Machaerium incorruptibile (Vell.) Benth. Source Classification	Others
5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran is a Phenols product that can be isolated from the herbs of Artemisia dracunculus. .

HY-N15335

Anti-inflammatory agent 98	Natural Products Paeonia lactiflora Pall. Plants Paeoniaceae Source Classification	Drug Derivative
Anti-inflammatory agent 98 (Compound 8) is a potent NO production inhibitor with an IC₅₀ value of 14.79 μM. Anti-inflammatory agent 98 is a benzofuran with anti-inflammatory activities, which is found in the roots of Paeonia lactiflora Pall .

HY-N17161

*(E)-5-Hydroxy-6-isoprenyl-2-(pent-1-en-1-yl)benzofuran-4-carbaldehyde*	Structural Classification Simple Phenylpropanols Marine natural products Phenylpropanoids Marine microorganism Source Classification	Drug Derivative
(E)-5-Hydroxy-6-isoprenyl-2-(pent-1-en-1-yl)benzofuran-4-carbaldehyde is a natural phenolic compound.

HY-N16768

Alangilignoside B	Structural Classification Lignans Solanum lyratum Thunberg Phenylpropanoids Solanaceae Plants Source Classification	Others
Alangilignoside B is a benzofuran-type neolignan glycoside compound that can be naturally extracted from the stems of Alangium premnifolium .

HY-N1777R

3,4-Dimethoxybenzamide (Standard)	Structural Classification Natural Products Microorganisms Source Classification	Reference Standards Drug Intermediate
3,4-Dimethoxybenzamide (Standard) is the analytical standard of 3,4-Dimethoxybenzamide. This product is intended for research and analytical applications. 3,4-Dimethoxybenzamide, amide, is isolated from the solid culture of Streptoverticillium morookaense. 3,4-Dimethoxybenzamide can be used as the starting material to preparation Itopride hydrochloride[1][2].

Cat. No.	Product Name	Chemical Structure

HY-B0556AS

Tetrahydrozoline-d4 hydrochloride
Tetrahydrozoline-d₄ (hydrochloride) is the deuterium labeled Tetrahydrozoline hydrochloride. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .

HY-B0374S

Moxonidine-d4

Moxonidine-d₄ (BDF5895-d₄) is the deuterium labeled Moxonidine (HY-B0374). Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I₁-R) agonist. Moxonidine activates imidazoline I₁ receptors and α₂ adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis .

HY-B0374S1

Moxonidine-d7

Moxonidine-d₇ is deuterated labeled Moxonidine (HY-B0374). Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I₁-R) agonist. Moxonidine activates imidazoline I₁ receptors and α₂ adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis .

HY-B0374AS

Moxonidine-13C,d3 hydrochloride

Moxonidine- ¹³C,d₃ hydrochloride is ¹³C and deuterated labeled Moxonidine hydrochloride (HY-B0374A). Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I₁-R) agonist. Moxonidine activates imidazoline I₁ receptors and α₂ adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis .

HY-B0374S2

Moxonidine-d3

Moxonidine-d₃ (BDF5895-d₃) is deuterium labeled Moxonidine (HY-B0374). Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I₁-R) agonist. Moxonidine activates imidazoline I₁ receptors and α₂ adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis .

HY-101392S

Harmane-d1

Harmane-d is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC₅₀=30 nM) over α2-adrenoceptor (IC₅₀=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC₅₀s=0.5 and 5 μM for human MAO A/B, respectively) .

HY-132772S

2-n-Butyl-4-[(2-bromoethoxy-d4)-3,5-diiodobenzoyl]benzofuran
2-n-Butyl-4-[(2-bromoethoxy-d₄)-3,5-diiodobenzoyl]benzofuran is the deuterium labeled 2-n-Butyl-4-[(2-bromoethoxy)-3,5-diiodobenzoyl]benzofuran .

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