1. Immunology/Inflammation
    NF-κB
    Metabolic Enzyme/Protease
  2. Reactive Oxygen Species
  3. Euparin

Euparin 

Cat. No.: HY-N4161
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Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects.

For research use only. We do not sell to patients.

Euparin Chemical Structure

Euparin Chemical Structure

CAS No. : 532-48-9

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Description

Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects[1][2].

In Vitro

In Vero cells, Euparin shows antiviral activity against poliovirus types 1, 2, and 3 with EC50 values of 0.47 µg/mL, 0.12 µg/mL, and 0.15 µg/mL, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Euparin (8, 16 and 32 mg/kg) reduces depression-like behavior in Chronic Unpredictable Mild Stress (CUMS) model of mice. All doses of Euparin are found to increase the contents of monoamine neurotransmitter and decrease monoamine oxidase and reactive oxygen species (ROS) levels in brain of depression mice. Euparin restores CUMS-induced decrease of Spermidine/Spermine N1-Acetyltransferase 1 (SAT1), N-methyl-D-aspartate receptor subtype 2B (NMDAR2B) and brain derived neurotrophic factor (BDNF) expression[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

216.23

Formula

C₁₃H₁₂O₃

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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