2. Neuronal Signaling
  3. Imidazoline Receptor
  4. BU226 hydrochloride

BU226 hydrochloride is a selective imidazoline 2 (I2) receptors ligand with an Ki of 1.4 nM for I2 and an IC50 of 534.5 nM for I1. BU226 hydrochloride can be used for researching antidepressant.

For research use only. We do not sell to patients.

BU226 hydrochloride Chemical Structure

BU226 hydrochloride Chemical Structure

CAS No. : 1186195-56-1

Size Price Stock Quantity
5 mg USD 180 In-stock
10 mg USD 280 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

BU226 hydrochloride Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

BU226 hydrochloride is a selective imidazoline 2 (I2) receptors ligand with an Ki of 1.4 nM for I2 and an IC50 of 534.5 nM for I1. BU226 hydrochloride can be used for researching antidepressant[1].

IC50 & Target

Ki: 1.4 nM (I2)[1]
IC50: 534.5 nM (I1)[1]
Molecular Weight

233.70

Formula

C12H12ClN3
CAS No.
Appearance

Solid

Color

White to light brown

SMILES

C1(C2=NCCN2)=CC3=C(C=N1)C=CC=C3.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (106.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2790 mL 21.3950 mL 42.7899 mL
5 mM 0.8558 mL 4.2790 mL 8.5580 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.2790 mL 21.3950 mL 42.7899 mL 106.9748 mL
5 mM 0.8558 mL 4.2790 mL 8.5580 mL 21.3950 mL
10 mM 0.4279 mL 2.1395 mL 4.2790 mL 10.6975 mL
15 mM 0.2853 mL 1.4263 mL 2.8527 mL 7.1317 mL
20 mM 0.2139 mL 1.0697 mL 2.1395 mL 5.3487 mL
25 mM 0.1712 mL 0.8558 mL 1.7116 mL 4.2790 mL
30 mM 0.1426 mL 0.7132 mL 1.4263 mL 3.5658 mL
40 mM 0.1070 mL 0.5349 mL 1.0697 mL 2.6744 mL
50 mM 0.0856 mL 0.4279 mL 0.8558 mL 2.1395 mL
60 mM 0.0713 mL 0.3566 mL 0.7132 mL 1.7829 mL
80 mM 0.0535 mL 0.2674 mL 0.5349 mL 1.3372 mL
100 mM 0.0428 mL 0.2139 mL 0.4279 mL 1.0697 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

BU226 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BU2261186195-56-1BU 226BU-226Imidazoline ReceptorantidepressantInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
BU226 hydrochloride
Cat. No.:
HY-101380A
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.