2-APB hydrochloride

Cat. No.: HY-W721302 Purity: 99.9%: Data Sheet
COA

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Handling Instructions
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2-APB is an analog of 6-APB, a benzofuran derivative and a psychoactive substance. Certain benzofuran derivatives have monoamine oxidase-A inhibitory activity .

For research use only. We do not sell to patients.

2-APB hydrochloride Chemical Structure

CAS No. : 3710-48-3

Size	Stock	Quantity
500 μg	In-stock	Estimated Time of Arrival: December 31
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	Get quote
10 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

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MAO-A MAO-B

Biological Activity
Purity & Documentation
References
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Description

2-APB is an analog of 6-APB, a benzofuran derivative and a psychoactive substance. Certain benzofuran derivatives have monoamine oxidase-A inhibitory activity ^[1]^[1].

IC₅₀ & Target

MAO-A

Molecular Weight

211.69

Formula

C₁₁H₁₄ClNO

CAS No.

3710-48-3

Appearance

Solid

Color

White to off-white

SMILES

CC(CC1=CC2=CC=CC=C2O1)N.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 10 mg/mL (47.24 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.7239 mL	23.6194 mL	47.2389 mL
5 mM	0.9448 mL	4.7239 mL	9.4478 mL
10 mM	0.4724 mL	2.3619 mL	4.7239 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.9%

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Data Sheet (273 KB) SDS (393 KB)

COA (250 KB)

Handling Instructions (2659 KB)

References

[1]. Vallejos G, et al. Heteroarylisopropylamines as MAO inhibitors. Bioorg Med Chem. 2005 Jul 15;13(14):4450-7. [Content Brief]

[2]. Stanczuk A, et al. Identification of (2-aminopropyl)benzofuran (APB) phenyl ring positional isomers in internet purchased products. Drug Test Anal. 2013 Apr;5(4):270-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.7239 mL	23.6194 mL	47.2389 mL	118.0972 mL
	5 mM	0.9448 mL	4.7239 mL	9.4478 mL	23.6194 mL
	10 mM	0.4724 mL	2.3619 mL	4.7239 mL	11.8097 mL
	15 mM	0.3149 mL	1.5746 mL	3.1493 mL	7.8731 mL
	20 mM	0.2362 mL	1.1810 mL	2.3619 mL	5.9049 mL
	25 mM	0.1890 mL	0.9448 mL	1.8896 mL	4.7239 mL
	30 mM	0.1575 mL	0.7873 mL	1.5746 mL	3.9366 mL
	40 mM	0.1181 mL	0.5905 mL	1.1810 mL	2.9524 mL