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Cat. No.: HY-106504

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Aganodine

Aganodine is a guanidine that activates presynaptic imidazoline receptors and can inhibit electrically evoked [³H]-norepinephrine release.

For research use only. We do not sell to patients.

CAS No.: 86696-87-9
Formula: C₉H₁₀Cl₂N₄
Molecular Weight:245.11

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Aganodine Chemical Structure

CAS No.: 86696-87-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Aganodine is a guanidine that activates presynaptic imidazoline receptors and can inhibit electrically evoked [³H]-norepinephrine release^[1]^[2]^[3].

Chemical Information

CAS No. 86696-87-9
Molecular Weight 245.11
Formula C₉H₁₀Cl₂N₄
SMILES

ClC1=CC=C(C2=C1CN(C2)NC(N)=N)Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Molderings G J, et al. Presynaptic imidazoline receptors and non‐adrenoceptor [3H]‐idazoxan binding sites in human cardiovascular tissues[J]. British journal of pharmacology, 1997, 122(1): 43-50.

[2]. Göthert M, et al. α2‐Adrenoceptor‐independent inhibition by imidazolines and guanidines of noradrenaline release from peripheral, but not central noradrenergic neurons[J]. Annals of the New York Academy of Sciences, 1995, 763(1): 405-419.

[3]. Schlicker E, et al. Effects of imidazolines in noradrenaline release in brain: An investigation into their relationship to imidazoline, α2 and H3 receptors[J]. Neurochemistry international, 1997, 30(1): 73-83. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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