2. Garsevil

Garsevil (LSL 60101) is a biphasic, selective imidazoline I2 receptor (I2-IR) ligand, with a pKi of 9.03 and a Ki of 0.9 nM at the high-affinity site, and a pKi of 5.25 and a Ki of 5.6 nM at the low-affinity site. Garsevil is applicable to research related to Alzheimer's disease.

For research use only. We do not sell to patients.

Garsevil

Garsevil Chemical Structure

CAS No. : 150985-54-9

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Garsevil Related Antibodies

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Description

Garsevil (LSL 60101) is a biphasic, selective imidazoline I2 receptor (I2-IR) ligand, with a pKi of 9.03 and a Ki of 0.9 nM at the high-affinity site, and a pKi of 5.25 and a Ki of 5.6 nM at the low-affinity site. Garsevil is applicable to research related to Alzheimer's disease[1].

In Vitro

Garsevil exhibits excellent selectivity for I2-IR over α2-adrenergic receptors (α2-AR), with an I2/α2 selectivity ratio of 7244.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Garsevil Related Antibodies
Molecular Weight

184.20

Formula

C11H8N2O
CAS No.
SMILES

N=1C=CNC1C=2OC=3C=CC=CC3C2
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Garsevil150985-54-9LSL 60101LSL60101LSL-60101neuroinflammatory gene expressionα2-adrenergic receptorsalzheimer’s diseaseadult Sprague-Dawley ratshuman I2-IRimidazoline I2 receptorhuman prefrontal cortex I2-imidazoline receptorshippocampal FADD protein5-month-old female 5xFAD miceadult CD-1 miceInhibitorinhibitorinhibit

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