2. Cell Cycle/DNA Damage Antibody-drug Conjugate/ADC Related Autophagy Anti-infection Apoptosis
  3. Topoisomerase DNA/RNA Synthesis ADC Payload Autophagy Bacterial Antibiotic Apoptosis
  4. Daunorubicin

Daunorubicin  (Synonyms: Daunomycin; RP 13057; Rubidomycin)

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Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor.

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CAS. Nr. : 20830-81-3

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Based on 37 publication(s) in Google Scholar

Other Forms of Daunorubicin:

Daunorubicin Related Antibodies

Top Publications Citing Use of Products

37 Publications Citing Use of MCE Daunorubicin

Cell Proliferation/Viability Assay
Apoptosis Analysis
Cell Imaging/Staining

    Daunorubicin purchased from MedChemExpress. Usage Cited in: Interdiscip Med. 2025 Sep 1;3(5):e70053.

    Cell viability analysis of OCI-AML2 cells expressing the indicated sgRNAs following treatment with increasing concentrations of Daunorubicin hydrochloride (3 days), assessed using the CCK-8 assay.

    Daunorubicin purchased from MedChemExpress. Usage Cited in: Interdiscip Med. 2025 Sep 1;3(5):e70053.

    OCI-AML2 cells expressing indicated sgRNAs were treated with DMSO or Daunorubicin hydrochloride (10 nM), and viable cells were counted every 3–4 days.

    Daunorubicin purchased from MedChemExpress. Usage Cited in: Cell Mol Immunol. 2023 Jan;20(1):51-64.  [Abstract]

    Comparison of drug (Epirubicin hydrochloride, EPI; Daunorubicin hydrochloride, DNR; Vinorelbine ditartrate, VNR; Oxaliplatin, OXA; Vincristine, VCR; Artemisinin, ART; Colchicine, COL) cytotoxicity to TC1 cells at the indicated doses and time points measured with CCK-8 assays. R.U. (Relative unit) was calculated from the average O.D. values in each condition as the indicator of cell viability (n = 3).

    Daunorubicin purchased from MedChemExpress. Usage Cited in: J Transl Med. 2022 Jul 6;20(1):304.  [Abstract]

    IC50 curves of Daunorubicin hydrochloride (1.25-1280 nM; 48 h) in U937 and Molm-13 cells transfected with lentivirus targeting SEMA4D or control. Transduced AML cells were treated with daunorubicin for 48 h and then measured by CCK-8 analysis.

    Daunorubicin purchased from MedChemExpress. Usage Cited in: J Transl Med. 2022 Jul 6;20(1):304.  [Abstract]

    Cell apoptosis rate of U937 and Molm-13 cells transfected with lentivirus targeting SEMA4D or control after Daunorubicin hydrochloride (10-80 nM) treatment was detected by flow cytometry using Annexin V-APC /PI staining.

    Daunorubicin purchased from MedChemExpress. Usage Cited in: Pharmaceutics. 2021 May 5;13(5):661.

    Primary AML cells were treated with Daunorubicin hydrochloride (DNR, 8-32 μM) and Erastin (5 μM) for 48 h, and cell viability was assessed using the CCK-8 assay.

    Daunorubicin purchased from MedChemExpress. Usage Cited in: Pharmaceutics. 2021 May 5;13(5):661.

    HL-60 cells were pretreated with CCL20 for 30 min, followed by Daunorubicin hydrochloride (DNR, 1.6, 3.2 μM) treatment for 48 h, and lipid peroxidation level were measured.

    Alle Topoisomerase Isoform-spezifische Produkte anzeigen:

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    Topoisomerase Topo I Topo II DNA gyrase

    Alle DNA/RNA Synthesis Isoform-spezifische Produkte anzeigen:

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    RNASE L DNA Polymerases RNA Polymerases Helicases DNA Ligase

    Alle ADC Payload Isoform-spezifische Produkte anzeigen:

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    Beschreibung

    Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor[1][2][4][5].

    IC50 & Target[1][2]

    Topoisomerase II

     

    Daunorubicins/Doxorubicins

     

    Cellular Effect
    Cell Line Type Value Description References
    4T1 IC50
    0.3 3
    Compound: Daunorubicin
    Cytotoxicity against mouse 4T1 cells after 72 hrs by MTT assay
    Cytotoxicity against mouse 4T1 cells after 72 hrs by MTT assay
    		[PMID: 30654237]
    4T1 IC50
    0.3 3
    Compound: Daunorubicin
    Cytotoxicity against mouse 4T1 cells after 72 hrs by MTT assay
    Cytotoxicity against mouse 4T1 cells after 72 hrs by MTT assay
    		[PMID: 30654237]
    A2780 ADR GI50
    0.575 3
    Compound: Daunorubicin
    Inhibition of cell growth in Daunorubicin resistant human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    Inhibition of cell growth in Daunorubicin resistant human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    4T1 IC50
    40.8 1
    Compound: Dau
    Cytostatic activity against mouse 4T1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against mouse 4T1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    A2780 ADR GI50
    0.01 3
    Compound: Daunorubicin
    Inhibition of daunorubicin sensitive human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    Inhibition of daunorubicin sensitive human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    A2058 IC50
    33.3 1
    Compound: Dau
    Cytostatic activity against human A2058 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human A2058 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    4T1 IC50
    0.3 3
    Compound: Daunorubicin
    Cytotoxicity against mouse 4T1 cells after 72 hrs by MTT assay
    Cytotoxicity against mouse 4T1 cells after 72 hrs by MTT assay
    		[PMID: 30654237]
    A549 GI50
    0.08 3
    Compound: daunorubicin
    Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay
    		[PMID: 19968258]
    A2780 ADR GI50
    0.01 3
    Compound: Daunorubicin
    Inhibition of daunorubicin sensitive human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    Inhibition of daunorubicin sensitive human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    A549 IC50
    0.53 3
    Compound: Daunorubicin
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    4T1 IC50
    40.8 1
    Compound: Dau
    Cytostatic activity against mouse 4T1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against mouse 4T1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    A2780 ADR GI50
    0.575 3
    Compound: Daunorubicin
    Inhibition of cell growth in Daunorubicin resistant human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    Inhibition of cell growth in Daunorubicin resistant human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    A549 IC50
    0.08 3
    Compound: Daunorubicin
    Antiproliferative activity against human A549 cells by XTT assay
    Antiproliferative activity against human A549 cells by XTT assay
    		[PMID: 25467291]
    A2058 IC50
    33.3 1
    Compound: Dau
    Cytostatic activity against human A2058 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human A2058 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    A549 GI50
    0.08 3
    Compound: daunorubicin
    Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay
    		[PMID: 19968258]
    A2780 ADR GI50
    0.01 3
    Compound: Daunorubicin
    Inhibition of daunorubicin sensitive human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    Inhibition of daunorubicin sensitive human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    A549 IC50
    0.15 3
    Compound: Daunorubicin
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    		[PMID: 30902399]
    A549 IC50
    0.08 3
    Compound: Daunorubicin
    Antiproliferative activity against human A549 cells by XTT assay
    Antiproliferative activity against human A549 cells by XTT assay
    		[PMID: 25467291]
    A2780 ADR GI50
    0.575 3
    Compound: Daunorubicin
    Inhibition of cell growth in Daunorubicin resistant human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    Inhibition of cell growth in Daunorubicin resistant human A2780 ADR cells expressing P-gp measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    A549 IC50
    0.15 3
    Compound: Daunorubicin
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    		[PMID: 30902399]
    A549 IC50
    0.51 3
    Compound: Daunorubicin
    Cytotoxicity in human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    A549 IC50
    0.51 3
    Compound: Daunorubicin
    Cytotoxicity in human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    B16 EC50
    0.16 3
    Compound: daunomycin
    Cytotoxicity that caused a 50% reduction in absorbance at 490 nm in B16 mouse melanoma cells using MTS assay.
    Cytotoxicity that caused a 50% reduction in absorbance at 490 nm in B16 mouse melanoma cells using MTS assay.
    		[PMID: 11020285]
    A549 GI50
    0.08 3
    Compound: daunorubicin
    Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay
    		[PMID: 19968258]
    BHK-21 IC50
    0.09 3
    Compound: Daunorubicin
    Cytotoxicity against BHK21 cells after 72 hrs by MTT assay
    Cytotoxicity against BHK21 cells after 72 hrs by MTT assay
    		[PMID: 30654237]
    A549 IC50
    0.53 3
    Compound: Daunorubicin
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    P388 IC50
    3 1
    Compound: DNR
    Compound was evaluated for cytotoxicity against P388 leukemia cell line.
    Compound was evaluated for cytotoxicity against P388 leukemia cell line.
    		[PMID: 10479297]
    A549 IC50
    0.08 3
    Compound: Daunorubicin
    Antiproliferative activity against human A549 cells by XTT assay
    Antiproliferative activity against human A549 cells by XTT assay
    		[PMID: 25467291]
    A549 IC50
    68.2 1
    Compound: Dau
    Cytostatic activity against human A549 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human A549 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    COLO 205 IC50
    0.5 6
    Compound: daunorubicin
    Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay
    Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    A549 IC50
    0.15 3
    Compound: Daunorubicin
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    		[PMID: 30902399]
    ACHN IC50
    63 1
    Compound: daunorubicin
    Antiproliferative activity against drug resistant ACHN cell line expressing MDR1 by Alamar Blue assay
    Antiproliferative activity against drug resistant ACHN cell line expressing MDR1 by Alamar Blue assay
    		[PMID: 17286393]
    NCI-H460 IC50
    3.5 1
    Compound: Daunomycin
    Evaluated in vitro for antiproliferative activity against NIC-H460 cell lines derived from large cell carcinoma of the lung
    Evaluated in vitro for antiproliferative activity against NIC-H460 cell lines derived from large cell carcinoma of the lung
    		10.1016/S0960-894X(97)10152-4
    A549 IC50
    0.51 3
    Compound: Daunorubicin
    Cytotoxicity in human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    B16 EC50
    0.16 3
    Compound: daunomycin
    Cytotoxicity that caused a 50% reduction in absorbance at 490 nm in B16 mouse melanoma cells using MTS assay.
    Cytotoxicity that caused a 50% reduction in absorbance at 490 nm in B16 mouse melanoma cells using MTS assay.
    		[PMID: 11020285]
    NSCLC IC50
    3.9 1
    Compound: Daunomycin
    Evaluated in vitro for antiproliferative activity against NYH cell lines derived from small cell lung cancer
    Evaluated in vitro for antiproliferative activity against NYH cell lines derived from small cell lung cancer
    		10.1016/S0960-894X(97)10152-4
    A549 IC50
    0.53 3
    Compound: Daunorubicin
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    B16 IC50
    8.9 1
    Compound: Dau
    Cytostatic activity against mouse B16 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against mouse B16 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    CT26.WT IC50
    0.42 3
    Compound: Daunorubicin
    Cytotoxicity against mouse CT26.WT cells after 72 hrs by MTT assay
    Cytotoxicity against mouse CT26.WT cells after 72 hrs by MTT assay
    		[PMID: 30654237]
    A549 IC50
    199 1
    Compound: 1a; DNR
    Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
    		[PMID: 38412432]
    BHK-21 IC50
    0.09 3
    Compound: Daunorubicin
    Cytotoxicity against BHK21 cells after 72 hrs by MTT assay
    Cytotoxicity against BHK21 cells after 72 hrs by MTT assay
    		[PMID: 30654237]
    A549 IC50
    68.2 1
    Compound: Dau
    Cytostatic activity against human A549 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human A549 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    COLO 205 IC50
    0.5 6
    Compound: daunorubicin
    Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay
    Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    DA-3 cell line IC50
    1.9 3
    Compound: DNR
    Cytotoxicity against mouse DA-3 cells after 24 hrs by XTT assay
    Cytotoxicity against mouse DA-3 cells after 24 hrs by XTT assay
    		[PMID: 24900668]
    Detroit 551 GI50
    1.77 3
    Compound: DAR
    Cytotoxicity against human Detroit 551 cells after 72 hrs by XTT assay
    Cytotoxicity against human Detroit 551 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    CT26.WT IC50
    0.42 3
    Compound: Daunorubicin
    Cytotoxicity against mouse CT26.WT cells after 72 hrs by MTT assay
    Cytotoxicity against mouse CT26.WT cells after 72 hrs by MTT assay
    		[PMID: 30654237]
    CT26.WT IC50
    126 1
    Compound: Dau
    Cytostatic activity against mouse CT26.WT cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against mouse CT26.WT cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    DU-145 IC50
    0.09 3
    Compound: DAU
    Antiproliferative activity against human DU145 cells after 72 hrs by MTS assay
    Antiproliferative activity against human DU145 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    ACHN IC50
    63 1
    Compound: daunorubicin
    Antiproliferative activity against drug resistant ACHN cell line expressing MDR1 by Alamar Blue assay
    Antiproliferative activity against drug resistant ACHN cell line expressing MDR1 by Alamar Blue assay
    		[PMID: 17286393]
    DA-3 cell line IC50
    1.9 3
    Compound: DNR
    Cytotoxicity against mouse DA-3 cells after 24 hrs by XTT assay
    Cytotoxicity against mouse DA-3 cells after 24 hrs by XTT assay
    		[PMID: 24900668]
    DU-145 IC50
    0.13 3
    Compound: 37
    Cytotoxicity against human DU-145 cells assessed as cell growth inhibition
    Cytotoxicity against human DU-145 cells assessed as cell growth inhibition
    		[PMID: 33143937]
    H69AR GI50
    3.84 3
    Compound: Daunorubicin
    Inhibition of cell growth in Daunorubicin resistant human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    Inhibition of cell growth in Daunorubicin resistant human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    B16 EC50
    0.16 3
    Compound: daunomycin
    Cytotoxicity that caused a 50% reduction in absorbance at 490 nm in B16 mouse melanoma cells using MTS assay.
    Cytotoxicity that caused a 50% reduction in absorbance at 490 nm in B16 mouse melanoma cells using MTS assay.
    		[PMID: 11020285]
    Detroit 551 GI50
    1.77 3
    Compound: DAR
    Cytotoxicity against human Detroit 551 cells after 72 hrs by XTT assay
    Cytotoxicity against human Detroit 551 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    H69AR GI50
    0.361 3
    Compound: Daunorubicin
    Inhibition of daunorubicin sensitive human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    Inhibition of daunorubicin sensitive human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    B16 IC50
    8.9 1
    Compound: Dau
    Cytostatic activity against mouse B16 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against mouse B16 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    DU-145 IC50
    0.09 3
    Compound: DAU
    Antiproliferative activity against human DU145 cells after 72 hrs by MTS assay
    Antiproliferative activity against human DU145 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    H69AR IC50
    >1 3
    Compound: daunorubicin
    Antiproliferative activity against drug resistant H69AR cell line expressing MRP1 by Alamar Blue assay
    Antiproliferative activity against drug resistant H69AR cell line expressing MRP1 by Alamar Blue assay
    		[PMID: 17286393]
    B16 IC50
    9.2 1
    Compound: Daunomycin
    In vitro antiproliferative activity against B16 cell lines
    In vitro antiproliferative activity against B16 cell lines
    		10.1016/S0960-894X(97)10152-4
    DU-145 IC50
    24.5 1
    Compound: Dau
    Cytostatic activity against human DU145 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human DU145 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    HCT-116 IC50
    0.21 3
    Compound: Daunorubicin
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    H69AR IC50
    > 1000 1
    Compound: daunorubicin
    Antiproliferative activity against drug resistant H69AR cell line expressing MRP1 by Alamar Blue assay
    Antiproliferative activity against drug resistant H69AR cell line expressing MRP1 by Alamar Blue assay
    		[PMID: 17286393]
    H69AR GI50
    0.361 3
    Compound: Daunorubicin
    Inhibition of daunorubicin sensitive human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    Inhibition of daunorubicin sensitive human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    YOSHIDA IC50
    7.4 1
    Compound: Daunomycin
    In vitro antiproliferative activity against Yoshida cell lines
    In vitro antiproliferative activity against Yoshida cell lines
    		10.1016/S0960-894X(97)10152-4
    H69AR GI50
    3.84 3
    Compound: Daunorubicin
    Inhibition of cell growth in Daunorubicin resistant human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    Inhibition of cell growth in Daunorubicin resistant human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    B16 IC50
    8.9 1
    Compound: Dau
    Cytostatic activity against mouse B16 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against mouse B16 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    BHK-21 IC50
    0.09 3
    Compound: Daunorubicin
    Cytotoxicity against BHK21 cells after 72 hrs by MTT assay
    Cytotoxicity against BHK21 cells after 72 hrs by MTT assay
    		[PMID: 30654237]
    HCT-116 IC50
    0.21 3
    Compound: Daunorubicin
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    B16 IC50
    9.2 1
    Compound: Daunomycin
    In vitro antiproliferative activity against B16 cell lines
    In vitro antiproliferative activity against B16 cell lines
    		10.1016/S0960-894X(97)10152-4
    HEK293 IC50
    12.55 3
    Compound: Daunorubicin
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar Blue assay
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar Blue assay
    		[PMID: 26937828]
    HCT-116 IC50
    127.1 1
    Compound: Dau
    Cytostatic activity against human HCT116 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human HCT116 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    HEK293 IC50
    12.55 3
    Compound: Daunorubicin
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar blue assay
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar blue assay
    		[PMID: 29190092]
    HCT-15 IC50
    > 400 1
    Compound: daunorubicin
    Antiproliferative activity against drug resistant HCT15 cell line expressing MDR1 by Alamar Blue assay
    Antiproliferative activity against drug resistant HCT15 cell line expressing MDR1 by Alamar Blue assay
    		[PMID: 17286393]
    HEK293 IC50
    1.2 3
    Compound: Daunonthicin
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 24 hrs by alamar blue assay
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 24 hrs by alamar blue assay
    		[PMID: 36449385]
    HEK293 IC50
    1.2 3
    Compound: Daunonthicin
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 24 hrs by alamar blue assay
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 24 hrs by alamar blue assay
    		[PMID: 36449385]
    HEK293 IC50
    11.17 3
    Compound: Daunorubicin
    Cytotoxicity in human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    HEK293 IC50
    11.17 3
    Compound: Daunorubicin
    Cytotoxicity against human HEK293 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against human HEK293 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    HEK293 IC50
    11.17 3
    Compound: Daunorubicin
    Cytotoxicity in human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    HEK293 IC50
    11.17 3
    Compound: Daunorubicin
    Cytotoxicity against human HEK293 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against human HEK293 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    COLO 205 IC50
    0.5 6
    Compound: daunorubicin
    Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay
    Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    CT26.WT IC50
    0.42 3
    Compound: Daunorubicin
    Cytotoxicity against mouse CT26.WT cells after 72 hrs by MTT assay
    Cytotoxicity against mouse CT26.WT cells after 72 hrs by MTT assay
    		[PMID: 30654237]
    HEK293 IC50
    12.55 3
    Compound: Daunorubicin
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar blue assay
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar blue assay
    		[PMID: 29190092]
    NCI-H1975 IC50
    13.3 1
    Compound: Dau
    Cytostatic activity against human NCI-H1975 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human NCI-H1975 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    CT26.WT IC50
    126 1
    Compound: Dau
    Cytostatic activity against mouse CT26.WT cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against mouse CT26.WT cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    HEK293 IC50
    12.55 3
    Compound: Daunorubicin
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar Blue assay
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar Blue assay
    		[PMID: 26937828]
    HL-60 IC50
    15 1
    Compound: DAU
    Antiproliferative activity against human HL-60 cells after 72 hrs by XTT assay
    Antiproliferative activity against human HL-60 cells after 72 hrs by XTT assay
    		[PMID: 33750129]
    HeLa IC50
    2.96 3
    Compound: daunomycin
    Cytotoxicity against human HeLa3 cell line by MTT assay
    Cytotoxicity against human HeLa3 cell line by MTT assay
    		[PMID: 16942037]
    K562 IC50
    15 1
    Compound: DNR
    Cytotoxicity against K562 cells by MTS
    Cytotoxicity against K562 cells by MTS
    		[PMID: 16451059]
    HeLa IC50
    2.96 3
    Compound: daunomycin
    Cytotoxicity against human HeLa3 cell line by MTT assay
    Cytotoxicity against human HeLa3 cell line by MTT assay
    		[PMID: 16942037]
    HepG2 IC50
    0.7 3
    Compound: Dauno
    Cytotoxicity against human HepG2 cells after 24 hrs by MTS assay
    Cytotoxicity against human HepG2 cells after 24 hrs by MTS assay
    		[PMID: 21094049]
    MDA-MB-361 IC50
    17 1
    Compound: Dauno
    The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) expressing LacZ (beta-galactosidase).
    The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) expressing LacZ (beta-galactosidase).
    		[PMID: 10395490]
    HepG2 IC50
    21.3 1
    Compound: Dau
    Cytostatic activity against human HepG2 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human HepG2 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    HeLa IC50
    8 3
    Compound: Daunorubicin (Daunomycin)
    TP_TRANSPORTER: inhibition of E217betaG uptake (E217betaG: 0.05 uM) in membrane vesicle from MRP1-expressing HeLa cells
    TP_TRANSPORTER: inhibition of E217betaG uptake (E217betaG: 0.05 uM) in membrane vesicle from MRP1-expressing HeLa cells
    		[PMID: 8621644]
    HL-60 GI50
    0.1 3
    Compound: Daunorubicin
    Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by trypan blue staining-based hemocytometric analysis
    Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by trypan blue staining-based hemocytometric analysis
    		[PMID: 25874335]
    HL-60 IC50
    15 1
    Compound: DAU
    Antiproliferative activity against human HL-60 cells after 72 hrs by XTT assay
    Antiproliferative activity against human HL-60 cells after 72 hrs by XTT assay
    		[PMID: 33750129]
    HepG2 IC50
    0.7 3
    Compound: Dauno
    Cytotoxicity against human HepG2 cells after 24 hrs by MTS assay
    Cytotoxicity against human HepG2 cells after 24 hrs by MTS assay
    		[PMID: 21094049]
    HT-29 GI50
    0.07 3
    Compound: daunorubicin
    Cytotoxicity against human HT-29 cells after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human HT-29 cells after 72 hrs by sulforhodamine B assay
    		[PMID: 19968258]
    HepG2 IC50
    9.12 3
    Compound: 92307396
    HARVARD: Cytotoxicity in HepG2 cell line
    HARVARD: Cytotoxicity in HepG2 cell line
    		[PMID: 22586124]
    HepG2 IC50
    2.99 3
    Compound: 92307396
    HARVARD: Inhibition of liver stage Plasmodium berghei infection in HepG2 cells
    HARVARD: Inhibition of liver stage Plasmodium berghei infection in HepG2 cells
    		[PMID: 22586124]
    HT-29 IC50
    0.2 3
    Compound: Dau, daunomycin
    Cytostatic activity against human HT-29 cells after 4 days by MTT assay
    Cytostatic activity against human HT-29 cells after 4 days by MTT assay
    		[PMID: 22480495]
    MES-SA IC50
    20 1
    Compound: daunorubicin
    Antiproliferative activity against drug sensitive Messa cell line by Alamar Blue assay
    Antiproliferative activity against drug sensitive Messa cell line by Alamar Blue assay
    		[PMID: 17286393]
    HT-29 IC50
    0.4 3
    Compound: Dauno
    Cytotoxicity against human HT-29 cells after 24 hrs by MTS assay
    Cytotoxicity against human HT-29 cells after 24 hrs by MTS assay
    		[PMID: 21094049]
    HL-60 GI50
    0.1 3
    Compound: Daunorubicin
    Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by trypan blue staining-based hemocytometric analysis
    Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by trypan blue staining-based hemocytometric analysis
    		[PMID: 25874335]
    HT-29 IC50
    133 1
    Compound: Daunomycin
    Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay
    		[PMID: 2778449]
    HT-29 IC50
    202.9 1
    Compound: Dau
    Cytostatic activity against human HT-29 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human HT-29 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    HL-60 IC50
    0.005 3
    Compound: daunorubicin
    In vitro inhibitory concentration against proliferation of HL60 cells
    In vitro inhibitory concentration against proliferation of HL60 cells
    		[PMID: 12877593]
    HL-60 IC50
    1.5 3
    Compound: daunorubicin
    In vitro inhibitory concentration against proliferation of HL60R cells
    In vitro inhibitory concentration against proliferation of HL60R cells
    		[PMID: 12877593]
    DLD-1 IC50
    30 3
    Compound: Daunorubicin
    Antiproliferative activity against human DLD-1 cells by WST-8 assay
    Antiproliferative activity against human DLD-1 cells by WST-8 assay
    		[PMID: 38408511]
    Jurkat IC50
    82.6 1
    Compound: Daunorubicin
    Cytotoxicity against Jurkat T lymphocytes by MTT assay
    Cytotoxicity against Jurkat T lymphocytes by MTT assay
    		[PMID: 16366602]
    HL-60 IC50
    0.04 3
    Compound: daunorubicin
    In vitro inhibitory concentration against proliferation of HL60R cells along with 5 (uM) verapamil
    In vitro inhibitory concentration against proliferation of HL60R cells along with 5 (uM) verapamil
    		[PMID: 12877593]
    DU-145 IC50
    0.09 3
    Compound: DAU
    Antiproliferative activity against human DU145 cells after 72 hrs by MTS assay
    Antiproliferative activity against human DU145 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    K562 IC50
    > 5 3
    Compound: DNR
    Cytotoxicity against Dox-resistant K562 cells by MTS
    Cytotoxicity against Dox-resistant K562 cells by MTS
    		[PMID: 16451059]
    DU-145 IC50
    0.13 3
    Compound: 37
    Cytotoxicity against human DU-145 cells assessed as cell growth inhibition
    Cytotoxicity against human DU-145 cells assessed as cell growth inhibition
    		[PMID: 33143937]
    K562 GI50
    0.0074 3
    Compound: DAR
    Cytotoxicity against human K562 cells after 72 hrs by XTT assay
    Cytotoxicity against human K562 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    MDA-MB-361 IC50
    21 1
    Compound: Dauno
    The compound was tested for extracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of stCPG2 prodrug
    The compound was tested for extracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of stCPG2 prodrug
    		[PMID: 10395490]
    HepG2 IC50
    21.3 1
    Compound: Dau
    Cytostatic activity against human HepG2 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human HepG2 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    DU-145 IC50
    24.5 1
    Compound: Dau
    Cytostatic activity against human DU145 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human DU145 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    K562 IC50
    0.45 6
    Compound: daunorubicin
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    HT-29 GI50
    0.07 3
    Compound: daunorubicin
    Cytotoxicity against human HT-29 cells after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human HT-29 cells after 72 hrs by sulforhodamine B assay
    		[PMID: 19968258]
    Detroit 551 GI50
    1.77 3
    Compound: DAR
    Cytotoxicity against human Detroit 551 cells after 72 hrs by XTT assay
    Cytotoxicity against human Detroit 551 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    K562 IC50
    1.49 6
    Compound: Daunorubicin
    Cytotoxicity against human K562 cells after 6 hrs by MTT assay
    Cytotoxicity against human K562 cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    HT-29 IC50
    0.2 3
    Compound: Dau, daunomycin
    Cytostatic activity against human HT-29 cells after 4 days by MTT assay
    Cytostatic activity against human HT-29 cells after 4 days by MTT assay
    		[PMID: 22480495]
    K562 IC50
    15 1
    Compound: DNR
    Cytotoxicity against K562 cells by MTS
    Cytotoxicity against K562 cells by MTS
    		[PMID: 16451059]
    HT-29 IC50
    0.4 3
    Compound: Dauno
    Cytotoxicity against human HT-29 cells after 24 hrs by MTS assay
    Cytotoxicity against human HT-29 cells after 24 hrs by MTS assay
    		[PMID: 21094049]
    K562 IC50
    15.2 6
    Compound: daunorubicin
    Cytotoxicity against human doxorubicin-resistant K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human doxorubicin-resistant K562 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    K562 IC50
    8.5 6
    Compound: Daunorubicin
    Cytotoxicity against human doxorubicin-resistant K562 cells after 6 hrs by MTT assay
    Cytotoxicity against human doxorubicin-resistant K562 cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    DU-145 IC50
    24.5 1
    Compound: Dau
    Cytostatic activity against human DU145 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human DU145 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    P388 IC50
    25 1
    Compound: Daunorubicin
    Antiproliferative activity against P388 cells by ELISA
    Antiproliferative activity against P388 cells by ELISA
    		[PMID: 17154505]
    KB IC50
    0.22 6
    Compound: daunorubicin
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    PC-3 IC50
    26 1
    Compound: Dau
    Cytostatic activity against human PC3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human PC3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    H69AR GI50
    0.361 3
    Compound: Daunorubicin
    Inhibition of daunorubicin sensitive human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    Inhibition of daunorubicin sensitive human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    KB IC50
    0.45 6
    Compound: Daunorubicin
    Cytotoxicity against human KB cells after 6 hrs by MTT assay
    Cytotoxicity against human KB cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    H69AR GI50
    3.84 3
    Compound: Daunorubicin
    Inhibition of cell growth in Daunorubicin resistant human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    Inhibition of cell growth in Daunorubicin resistant human NCI-H69AR cells expressing MRP1 measured for 72 hrs by MTT assay
    		[PMID: 29016119]
    KB IC50
    0.64 3
    Compound: Daunorubicin
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    		[PMID: 20363142]
    U-87MG ATCC IC50
    27.9 1
    Compound: Dau
    Cytostatic activity against human U87 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human U87 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    KB IC50
    2.07 3
    Compound: DNR
    In vitro cytotoxicity using human epidermoid carcinoma (KB-A1) cells
    In vitro cytotoxicity using human epidermoid carcinoma (KB-A1) cells
    		10.1016/0960-894X(96)00457-X
    P388 IC50
    28 1
    Compound: Daunomycin
    Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay
    Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay
    		[PMID: 2778449]
    H69AR IC50
    > 1000 1
    Compound: daunorubicin
    Antiproliferative activity against drug resistant H69AR cell line expressing MRP1 by Alamar Blue assay
    Antiproliferative activity against drug resistant H69AR cell line expressing MRP1 by Alamar Blue assay
    		[PMID: 17286393]
    HCT-116 IC50
    0.21 3
    Compound: Daunorubicin
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    K562 GI50
    0.0074 3
    Compound: DAR
    Cytotoxicity against human K562 cells after 72 hrs by XTT assay
    Cytotoxicity against human K562 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    KB IC50
    2.07 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the KB-3-1 resistant to adriamycin (ADR) subline KB-A1
    In vitro cytotoxic activity was evaluated using the KB-3-1 resistant to adriamycin (ADR) subline KB-A1
    		[PMID: 12443763]
    HCT-116 IC50
    127.1 1
    Compound: Dau
    Cytostatic activity against human HCT116 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human HCT116 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    A2058 IC50
    33.3 1
    Compound: Dau
    Cytostatic activity against human A2058 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human A2058 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    KB 3-1 IC50
    0.007 3
    Compound: DNR
    In vitro cytotoxicity using human epidermoid carcinoma (KB-3-1) cells
    In vitro cytotoxicity using human epidermoid carcinoma (KB-3-1) cells
    		10.1016/0960-894X(96)00457-X
    K562 IC50
    >5 3
    Compound: DNR
    Cytotoxicity against Dox-resistant K562 cells by MTS
    Cytotoxicity against Dox-resistant K562 cells by MTS
    		[PMID: 16451059]
    HCT-15 IC50
    > 400 1
    Compound: daunorubicin
    Antiproliferative activity against drug resistant HCT15 cell line expressing MDR1 by Alamar Blue assay
    Antiproliferative activity against drug resistant HCT15 cell line expressing MDR1 by Alamar Blue assay
    		[PMID: 17286393]
    KB 3-1 IC50
    0.007 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the human epidermoid carcinoma cell line KB-3-1
    In vitro cytotoxic activity was evaluated using the human epidermoid carcinoma cell line KB-3-1
    		[PMID: 12443763]
    L1210 IC50
    0.033 3
    Compound: DNR
    In vitro cytotoxicity using murine leukemia L1210 cells from american type culture collection.
    In vitro cytotoxicity using murine leukemia L1210 cells from american type culture collection.
    		10.1016/0960-894X(96)00457-X
    K562 IC50
    15.2 6
    Compound: daunorubicin
    Cytotoxicity against human doxorubicin-resistant K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human doxorubicin-resistant K562 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    K562 IC50
    8.5 6
    Compound: Daunorubicin
    Cytotoxicity against human doxorubicin-resistant K562 cells after 6 hrs by MTT assay
    Cytotoxicity against human doxorubicin-resistant K562 cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    HEK293 IC50
    1.2 3
    Compound: Daunonthicin
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 24 hrs by alamar blue assay
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 24 hrs by alamar blue assay
    		[PMID: 36449385]
    L1210 IC50
    0.04 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the murine leukemia L1210 cell line
    In vitro cytotoxic activity was evaluated using the murine leukemia L1210 cell line
    		[PMID: 12443763]
    K562 IC50
    0.45 6
    Compound: daunorubicin
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    HEK293 IC50
    11.17 3
    Compound: Daunorubicin
    Cytotoxicity in human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    L1210 ED50
    0.3 3
    Compound: Daunomycin
    Inhibition of DNA synthesis in mouse L1210 cells preincubated for 3 hrs followed by [3H]-thymidine addition measured after 1 hr by scintillation spectrometric analysis
    Inhibition of DNA synthesis in mouse L1210 cells preincubated for 3 hrs followed by [3H]-thymidine addition measured after 1 hr by scintillation spectrometric analysis
    		[PMID: 176359]
    K562 IC50
    1.49 6
    Compound: Daunorubicin
    Cytotoxicity against human K562 cells after 6 hrs by MTT assay
    Cytotoxicity against human K562 cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    HEK293 IC50
    11.17 3
    Compound: Daunorubicin
    Cytotoxicity against human HEK293 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity against human HEK293 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    L1210 ED50
    0.3 3
    Compound: Daunomycin
    Inhibition of RNA synthesis in mouse L1210 cells preincubated for 3 hrs followed by [3H]-uridine addition measured after 1 hr by scintillation spectrometric analysis
    Inhibition of RNA synthesis in mouse L1210 cells preincubated for 3 hrs followed by [3H]-uridine addition measured after 1 hr by scintillation spectrometric analysis
    		[PMID: 176359]
    K562 IC50
    0.141 3
    Compound: 15
    Cytotoxicity against human K562 cells incubated for 2 hrs by cell titre blue viability assay
    Cytotoxicity against human K562 cells incubated for 2 hrs by cell titre blue viability assay
    		[PMID: 37561481]
    HEK293 IC50
    12.55 3
    Compound: Daunorubicin
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar Blue assay
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar Blue assay
    		[PMID: 26937828]
    L1210 ED50
    0.33 3
    Compound: 2
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated uridine in the RNA of actively growing L1210 cells.
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated uridine in the RNA of actively growing L1210 cells.
    		[PMID: 7086816]
    HEK293 IC50
    12.55 3
    Compound: Daunorubicin
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar blue assay
    Cytotoxicity against HEK293 cells assessed as cell viability after 24 hrs by Alamar blue assay
    		[PMID: 29190092]
    MDA-MB-361 IC50
    36 1
    Compound: Dauno
    The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of CPG2 prodrug
    The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of CPG2 prodrug
    		[PMID: 10395490]
    L1210 ED50
    0.66 3
    Compound: 2
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated thymidine in the DNA of actively growing L1210 cells
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated thymidine in the DNA of actively growing L1210 cells
    		[PMID: 7086816]
    KB IC50
    0.22 6
    Compound: daunorubicin
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    L5178Y IC50
    0.3 3
    Compound: liposomal daunorubicin, DaunoXome
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    		[PMID: 23199479]
    KB IC50
    0.64 3
    Compound: Daunorubicin
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    		[PMID: 20363142]
    L5178Y IC50
    0.73 3
    Compound: Daunorubicin
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    		[PMID: 23199479]
    KB IC50
    0.45 6
    Compound: Daunorubicin
    Cytotoxicity against human KB cells after 6 hrs by MTT assay
    Cytotoxicity against human KB cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    L5178Y IC50
    2.32 3
    Compound: liposomal daunorubicin, DaunoXome
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    		[PMID: 23199479]
    MCF7 IC50
    39 1
    Compound: Daunomycin
    Evaluated in vitro for antiproliferative activity against MCF-7 cell lines model of hormone dependent breast cancer
    Evaluated in vitro for antiproliferative activity against MCF-7 cell lines model of hormone dependent breast cancer
    		10.1016/S0960-894X(97)10152-4
    L5178Y IC50
    7.73 3
    Compound: Daunorubicin
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    		[PMID: 23199479]
    KB IC50
    2.07 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the KB-3-1 resistant to adriamycin (ADR) subline KB-A1
    In vitro cytotoxic activity was evaluated using the KB-3-1 resistant to adriamycin (ADR) subline KB-A1
    		[PMID: 12443763]
    HL-60 GI50
    0.1 3
    Compound: Daunorubicin
    Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by trypan blue staining-based hemocytometric analysis
    Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by trypan blue staining-based hemocytometric analysis
    		[PMID: 25874335]
    LNCaP IC50
    0.1 3
    Compound: Dau, daunomycin
    Cytostatic activity against human LNCAP cells after 4 days by MTT assay
    Cytostatic activity against human LNCAP cells after 4 days by MTT assay
    		[PMID: 22480495]
    HL-60 IC50
    0.005 3
    Compound: daunorubicin
    In vitro inhibitory concentration against proliferation of HL60 cells
    In vitro inhibitory concentration against proliferation of HL60 cells
    		[PMID: 12877593]
    MCF7 IC50
    0.033 6
    Compound: Daunorubicin
    Cytotoxicity against human MCF7 cells after 6 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    KB IC50
    2.07 3
    Compound: DNR
    In vitro cytotoxicity using human epidermoid carcinoma (KB-A1) cells
    In vitro cytotoxicity using human epidermoid carcinoma (KB-A1) cells
    		10.1016/0960-894X(96)00457-X
    KB 3-1 IC50
    0.007 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the human epidermoid carcinoma cell line KB-3-1
    In vitro cytotoxic activity was evaluated using the human epidermoid carcinoma cell line KB-3-1
    		[PMID: 12443763]
    HL-60 IC50
    0.04 3
    Compound: daunorubicin
    In vitro inhibitory concentration against proliferation of HL60R cells along with 5 (uM) verapamil
    In vitro inhibitory concentration against proliferation of HL60R cells along with 5 (uM) verapamil
    		[PMID: 12877593]
    MCF7 IC50
    0.33 6
    Compound: daunorubicin
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    KB 3-1 IC50
    0.007 3
    Compound: DNR
    In vitro cytotoxicity using human epidermoid carcinoma (KB-3-1) cells
    In vitro cytotoxicity using human epidermoid carcinoma (KB-3-1) cells
    		10.1016/0960-894X(96)00457-X
    HL-60 IC50
    1.5 3
    Compound: daunorubicin
    In vitro inhibitory concentration against proliferation of HL60R cells
    In vitro inhibitory concentration against proliferation of HL60R cells
    		[PMID: 12877593]
    MCF7 IC50
    0.4 3
    Compound: Dau, daunomycin
    Cytostatic activity against human MCF7 cells after 4 days by MTT assay
    Cytostatic activity against human MCF7 cells after 4 days by MTT assay
    		[PMID: 22480495]
    P388/ADR IC50
    40 1
    Compound: Daunorubicin
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM verapamil by ELISA
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM verapamil by ELISA
    		[PMID: 17154505]
    HL-60 IC50
    15 1
    Compound: DAU
    Antiproliferative activity against human HL-60 cells after 72 hrs by XTT assay
    Antiproliferative activity against human HL-60 cells after 72 hrs by XTT assay
    		[PMID: 33750129]
    MCF7 IC50
    0.5 6
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 21109433]
    MCF7 IC50
    0.56 3
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    4T1 IC50
    40.8 1
    Compound: Dau
    Cytostatic activity against mouse 4T1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against mouse 4T1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    L1210 ED50
    0.66 3
    Compound: 1
    Compound was evaluated for the 50% inhibition of the incorporation of [3H]- thymidine in the DNA (inhibition of synthesis in leukemia L1210 cells)
    Compound was evaluated for the 50% inhibition of the incorporation of [3H]- thymidine in the DNA (inhibition of synthesis in leukemia L1210 cells)
    		[PMID: 3761325]
    MCF7 IC50
    0.65 3
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7 cells by XTT assay
    Antiproliferative activity against human MCF7 cells by XTT assay
    		[PMID: 25467291]
    L1210 ED50
    0.33 3
    Compound: 1
    Compound was evaluated for the 50% inhibition of the incorporation of [3H]- thymidine in the RNA (inhibition of synthesis in leukemia L1210 cells)
    Compound was evaluated for the 50% inhibition of the incorporation of [3H]- thymidine in the RNA (inhibition of synthesis in leukemia L1210 cells)
    		[PMID: 3761325]
    MCF7 GI50
    0.86 3
    Compound: DAR
    Cytotoxicity against human MCF7 cells after 72 hrs by XTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    L1210 ED50
    0.66 3
    Compound: 2
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated thymidine in the DNA of actively growing L1210 cells
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated thymidine in the DNA of actively growing L1210 cells
    		[PMID: 7086816]
    MCF7 IC50
    0.95 3
    Compound: DAU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    L1210 ED50
    0.33 3
    Compound: 2
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated uridine in the RNA of actively growing L1210 cells.
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated uridine in the RNA of actively growing L1210 cells.
    		[PMID: 7086816]
    HT-29 GI50
    0.07 3
    Compound: daunorubicin
    Cytotoxicity against human HT-29 cells after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human HT-29 cells after 72 hrs by sulforhodamine B assay
    		[PMID: 19968258]
    MCF7 IC50
    1.44 3
    Compound: Daunorubicin
    Cytotoxicity in human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    HT-29 IC50
    0.2 3
    Compound: Dau, daunomycin
    Cytostatic activity against human HT-29 cells after 4 days by MTT assay
    Cytostatic activity against human HT-29 cells after 4 days by MTT assay
    		[PMID: 22480495]
    MCF7 IC50
    286 1
    Compound: Dau
    Cytostatic activity against human MCF7 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human MCF7 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    L1210 ED50
    0.48 3
    Compound: 1
    Inhibition of DNA synthesis in mouse L1210 cells
    Inhibition of DNA synthesis in mouse L1210 cells
    		[PMID: 690999]
    HT-29 IC50
    0.4 3
    Compound: Dauno
    Cytotoxicity against human HT-29 cells after 24 hrs by MTS assay
    Cytotoxicity against human HT-29 cells after 24 hrs by MTS assay
    		[PMID: 21094049]
    MCF7 IC50
    33.9 3
    Compound: DNR
    Cytotoxicity against human MCF7 cells after 24 hrs by XTT assay
    Cytotoxicity against human MCF7 cells after 24 hrs by XTT assay
    		[PMID: 24900668]
    L1210 ED50
    0.66 3
    Compound: 1
    Inhibition of DNA synthesis in mouse L1210 cells
    Inhibition of DNA synthesis in mouse L1210 cells
    		[PMID: 423182]
    MCF7 IC50
    5.5 3
    Compound: Dauno
    Cytotoxicity against human MCF7 cells after 24 hrs by MTS assay
    Cytotoxicity against human MCF7 cells after 24 hrs by MTS assay
    		[PMID: 21094049]
    HT-29 IC50
    133 1
    Compound: Daunomycin
    Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay
    		[PMID: 2778449]
    L1210 ED50
    0.66 3
    Compound: 1
    Inhibition of DNA synthesis in mouse L1210 cells
    Inhibition of DNA synthesis in mouse L1210 cells
    		[PMID: 490536]
    HT-29 IC50
    202.9 1
    Compound: Dau
    Cytostatic activity against human HT-29 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human HT-29 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    MDA-MB-231 GI50
    0.02 3
    Compound: daunorubicin
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay
    		[PMID: 19968258]
    L1210 ED50
    0.3 3
    Compound: Daunomycin
    Inhibition of DNA synthesis in mouse L1210 cells preincubated for 3 hrs followed by [3H]-thymidine addition measured after 1 hr by scintillation spectrometric analysis
    Inhibition of DNA synthesis in mouse L1210 cells preincubated for 3 hrs followed by [3H]-thymidine addition measured after 1 hr by scintillation spectrometric analysis
    		[PMID: 176359]
    L1210 ED50
    0.23 3
    Compound: 1
    Inhibition of RNA synthesis in mouse L1210 cells
    Inhibition of RNA synthesis in mouse L1210 cells
    		[PMID: 690999]
    MDA-MB-231 IC50
    0.091 3
    Compound: Daunorubicin
    Antiproliferative activity against human MDA-MB-231 cells by XTT assay
    Antiproliferative activity against human MDA-MB-231 cells by XTT assay
    		[PMID: 25467291]
    L1210 ED50
    0.33 3
    Compound: 1
    Inhibition of RNA synthesis in mouse L1210 cells
    Inhibition of RNA synthesis in mouse L1210 cells
    		[PMID: 423182]
    MDA-MB-231 IC50
    52.9 1
    Compound: Dau
    Cytostatic activity against human MDA-MB-231 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human MDA-MB-231 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    L1210 ED50
    0.33 3
    Compound: 1
    Inhibition of RNA synthesis in mouse L1210 cells
    Inhibition of RNA synthesis in mouse L1210 cells
    		[PMID: 490536]
    MDA-MB-435 IC50
    129 1
    Compound: Daunorubicin
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    		[PMID: 17154505]
    MDA-MB-435 IC50
    79 1
    Compound: Daunorubicin
    Antiproliferative activity against MDA435/LCC6 cells by ELISA
    Antiproliferative activity against MDA435/LCC6 cells by ELISA
    		[PMID: 17154505]
    L1210 IC50
    0.04 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the murine leukemia L1210 cell line
    In vitro cytotoxic activity was evaluated using the murine leukemia L1210 cell line
    		[PMID: 12443763]
    MDA-MB-435 IC50
    977 1
    Compound: Daunorubicin
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells by ELISA
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells by ELISA
    		[PMID: 17154505]
    L1210 IC50
    0.033 3
    Compound: DNR
    In vitro cytotoxicity using murine leukemia L1210 cells from american type culture collection.
    In vitro cytotoxicity using murine leukemia L1210 cells from american type culture collection.
    		10.1016/0960-894X(96)00457-X
    MES-SA IC50
    0.021 3
    Compound: DNR
    The compound was evaluated for the growth inhibition of MES-SA uterine tumor cell lines using MTT assay.
    The compound was evaluated for the growth inhibition of MES-SA uterine tumor cell lines using MTT assay.
    		[PMID: 10698449]
    L1210 IC50
    0.03 3
    Compound: Daunorubicin
    Inhibitory activity was measured against murine L1210 leukemia cells.
    Inhibitory activity was measured against murine L1210 leukemia cells.
    		[PMID: 9733483]
    L5178Y IC50
    0.3 3
    Compound: liposomal daunorubicin, DaunoXome
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    		[PMID: 23199479]
    MES-SA IC50
    0.07 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the human uterine sarcoma cell line MES-SA
    In vitro cytotoxic activity was evaluated using the human uterine sarcoma cell line MES-SA
    		[PMID: 12443763]
    L5178Y IC50
    0.73 3
    Compound: Daunorubicin
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    		[PMID: 23199479]
    MES-SA IC50
    20 1
    Compound: daunorubicin
    Antiproliferative activity against drug sensitive Messa cell line by Alamar Blue assay
    Antiproliferative activity against drug sensitive Messa cell line by Alamar Blue assay
    		[PMID: 17286393]
    L5178Y IC50
    2.32 3
    Compound: liposomal daunorubicin, DaunoXome
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    		[PMID: 23199479]
    MES-SA IC50
    3 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the MES-SA multidrug-resistant subline MES-SA/Dx5
    In vitro cytotoxic activity was evaluated using the MES-SA multidrug-resistant subline MES-SA/Dx5
    		[PMID: 12443763]
    L5178Y IC50
    7.73 3
    Compound: Daunorubicin
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    		[PMID: 23199479]
    HeLa IC50
    0.1 3
    Compound: Daunorubicin
    Antiproliferative activity against human HeLa cells by WST-8 assay
    Antiproliferative activity against human HeLa cells by WST-8 assay
    		[PMID: 38408511]
    MES-SA/Dx5 IC50
    > 400 1
    Compound: daunorubicin
    Antiproliferative activity against drug resistant Messa/DX5 cell line expressing MDR1 by Alamar Blue assay
    Antiproliferative activity against drug resistant Messa/DX5 cell line expressing MDR1 by Alamar Blue assay
    		[PMID: 17286393]
    WALKER IC50
    47 1
    Compound: Daunomycin
    In vitro antiproliferative activity against Walker cell line
    In vitro antiproliferative activity against Walker cell line
    		10.1016/S0960-894X(97)10152-4
    HeLa IC50
    2.96 3
    Compound: daunomycin
    Cytotoxicity against human HeLa3 cell line by MTT assay
    Cytotoxicity against human HeLa3 cell line by MTT assay
    		[PMID: 16942037]
    MES-SA/Dx5 IC50
    0.014 3
    Compound: DNR
    The compound was evaluated for the growth inhibition of Dx5 w/PSC cell lines using MTT assay.
    The compound was evaluated for the growth inhibition of Dx5 w/PSC cell lines using MTT assay.
    		[PMID: 10698449]
    HeLa IC50
    8 3
    Compound: Daunorubicin (Daunomycin)
    TP_TRANSPORTER: inhibition of E217betaG uptake (E217betaG: 0.05 uM) in membrane vesicle from MRP1-expressing HeLa cells
    TP_TRANSPORTER: inhibition of E217betaG uptake (E217betaG: 0.05 uM) in membrane vesicle from MRP1-expressing HeLa cells
    		[PMID: 8621644]
    MES-SA/Dx5 IC50
    2 3
    Compound: DNR
    The compound was evaluated for the growth inhibition of Dx5 cell lines using MTT assay.
    The compound was evaluated for the growth inhibition of Dx5 cell lines using MTT assay.
    		[PMID: 10698449]
    NCI-H1650 IC50
    47.5 1
    Compound: Dau
    Cytostatic activity against human NCI-H1650 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human NCI-H1650 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    LNCaP IC50
    0.1 3
    Compound: Dau, daunomycin
    Cytostatic activity against human LNCAP cells after 4 days by MTT assay
    Cytostatic activity against human LNCAP cells after 4 days by MTT assay
    		[PMID: 22480495]
    MRC5 IC50
    0.078 3
    Compound: Daunorubicin
    Antiproliferative activity against human MRC5 cells by XTT assay
    Antiproliferative activity against human MRC5 cells by XTT assay
    		[PMID: 25467291]
    MDA-MB-231 IC50
    52.9 1
    Compound: Dau
    Cytostatic activity against human MDA-MB-231 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human MDA-MB-231 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    MRC5 IC50
    254.7 1
    Compound: Dau
    Cytostatic activity against human MRC5 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human MRC5 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    NCI/ADR-RES IC50
    51.62 3
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7/ADR cells incubated for 48 hrs by CCK-8 assay
    Antiproliferative activity against human MCF7/ADR cells incubated for 48 hrs by CCK-8 assay
    		[PMID: 33725657]
    MCF7 GI50
    0.86 3
    Compound: DAR
    Cytotoxicity against human MCF7 cells after 72 hrs by XTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    MCF7 IC50
    5.03 3
    Compound: DAR
    Anticancer activity against human MCF7 cells
    Anticancer activity against human MCF7 cells
    		[PMID: 21599000]
    NCI/ADR-RES IC50
    7.12 3
    Compound: Daunomycin
    Growth inhibition of human MCF7/ADR cells after 48 hrs by SRB assay
    Growth inhibition of human MCF7/ADR cells after 48 hrs by SRB assay
    		[PMID: 28246041]
    MCF7 IC50
    0.5 6
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 21109433]
    NCI-H1299 IC50
    0.096 3
    Compound: Daunorubicin
    Antiproliferative activity against human H1299 cells by XTT assay
    Antiproliferative activity against human H1299 cells by XTT assay
    		[PMID: 25467291]
    MCF7 IC50
    0.95 3
    Compound: DAU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    NCI-H1650 IC50
    47.5 1
    Compound: Dau
    Cytostatic activity against human NCI-H1650 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human NCI-H1650 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    Lewis lung carcinoma cell line IC50
    61 1
    Compound: Daunomycin
    In vitro antiproliferative activity against Lewis cell lines
    In vitro antiproliferative activity against Lewis cell lines
    		10.1016/S0960-894X(97)10152-4
    HepG2 IC50
    0.7 3
    Compound: Dauno
    Cytotoxicity against human HepG2 cells after 24 hrs by MTS assay
    Cytotoxicity against human HepG2 cells after 24 hrs by MTS assay
    		[PMID: 21094049]
    NCI-H1975 IC50
    13.3 1
    Compound: Dau
    Cytostatic activity against human NCI-H1975 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human NCI-H1975 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    MCF7 IC50
    0.56 3
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    HepG2 IC50
    2.99 3
    Compound: 92307396
    HARVARD: Inhibition of liver stage Plasmodium berghei infection in HepG2 cells
    HARVARD: Inhibition of liver stage Plasmodium berghei infection in HepG2 cells
    		[PMID: 22586124]
    NCI-H460 GI50
    0.38 3
    Compound: DAR
    Cytotoxicity against human NCI-H460 cells after 72 hrs by XTT assay
    Cytotoxicity against human NCI-H460 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    MCF7 IC50
    0.65 3
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7 cells by XTT assay
    Antiproliferative activity against human MCF7 cells by XTT assay
    		[PMID: 25467291]
    HepG2 IC50
    21.3 1
    Compound: Dau
    Cytostatic activity against human HepG2 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human HepG2 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    NCI-H69 IC50
    100 1
    Compound: daunorubicin
    Antiproliferative activity against drug sensitive NCI-H69 cell line by Alamar Blue assay
    Antiproliferative activity against drug sensitive NCI-H69 cell line by Alamar Blue assay
    		[PMID: 17286393]
    ACHN IC50
    63 1
    Compound: daunorubicin
    Antiproliferative activity against drug resistant ACHN cell line expressing MDR1 by Alamar Blue assay
    Antiproliferative activity against drug resistant ACHN cell line expressing MDR1 by Alamar Blue assay
    		[PMID: 17286393]
    HepG2 IC50
    22 3
    Compound: Daunorubicin
    Antiproliferative activity against human HepG2 cells by WST-8 assay
    Antiproliferative activity against human HepG2 cells by WST-8 assay
    		[PMID: 38408511]
    NIH3T3 IC50
    0.044 3
    Compound: Dounorubicin
    Intrinsic cytotoxicity against wild type mouse NIH/3T3 cells after 72 hrs by MTT assay
    Intrinsic cytotoxicity against wild type mouse NIH/3T3 cells after 72 hrs by MTT assay
    		[PMID: 18954040]
    MCF7 IC50
    0.4 3
    Compound: Dau, daunomycin
    Cytostatic activity against human MCF7 cells after 4 days by MTT assay
    Cytostatic activity against human MCF7 cells after 4 days by MTT assay
    		[PMID: 22480495]
    HepG2 IC50
    9.12 3
    Compound: 92307396
    HARVARD: Cytotoxicity in HepG2 cell line
    HARVARD: Cytotoxicity in HepG2 cell line
    		[PMID: 22586124]
    NIH3T3 IC50
    1.01 3
    Compound: Dounorubicin
    Intrinsic cytotoxicity against mouse NIH/3T3 cells overexpressing MDR1 after 72 hrs by MTT assay
    Intrinsic cytotoxicity against mouse NIH/3T3 cells overexpressing MDR1 after 72 hrs by MTT assay
    		[PMID: 18954040]
    NIH3T3 IC50
    1.8 3
    Compound: Dauno
    Cytotoxicity against mouse NIH/3T3 cells after 3 days by MTS assay
    Cytotoxicity against mouse NIH/3T3 cells after 3 days by MTS assay
    		[PMID: 21094049]
    MCF7 IC50
    5.5 3
    Compound: Dauno
    Cytotoxicity against human MCF7 cells after 24 hrs by MTS assay
    Cytotoxicity against human MCF7 cells after 24 hrs by MTS assay
    		[PMID: 21094049]
    OVCAR-3 IC50
    472.9 1
    Compound: Dau
    Cytostatic activity against human OVCAR3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human OVCAR3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    MCF7 IC50
    33.9 3
    Compound: DNR
    Cytotoxicity against human MCF7 cells after 24 hrs by XTT assay
    Cytotoxicity against human MCF7 cells after 24 hrs by XTT assay
    		[PMID: 24900668]
    MCF7 IC50
    0.33 6
    Compound: daunorubicin
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    Jurkat IC50
    82.6 1
    Compound: Daunorubicin
    Cytotoxicity against Jurkat T lymphocytes by MTT assay
    Cytotoxicity against Jurkat T lymphocytes by MTT assay
    		[PMID: 16366602]
    P388 IC50
    25 1
    Compound: Daunorubicin
    Antiproliferative activity against P388 cells by ELISA
    Antiproliferative activity against P388 cells by ELISA
    		[PMID: 17154505]
    MCF7 IC50
    0.033 6
    Compound: Daunorubicin
    Cytotoxicity against human MCF7 cells after 6 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    P388 IC50
    28 1
    Compound: Daunomycin
    Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay
    Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay
    		[PMID: 2778449]
    MCF7 IC50
    1.44 3
    Compound: Daunorubicin
    Cytotoxicity in human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    P388/ADR IC50
    106 1
    Compound: Daunorubicin
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    		[PMID: 17154505]
    P388/ADR IC50
    2111 1
    Compound: Daunorubicin
    Antiproliferative activity against adriamycin resistant P388 cells by ELISA
    Antiproliferative activity against adriamycin resistant P388 cells by ELISA
    		[PMID: 17154505]
    A549 IC50
    68.2 1
    Compound: Dau
    Cytostatic activity against human A549 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human A549 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    K562 GI50
    0.0074 3
    Compound: DAR
    Cytotoxicity against human K562 cells after 72 hrs by XTT assay
    Cytotoxicity against human K562 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    MDA-MB-231 GI50
    0.02 3
    Compound: daunorubicin
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay
    		[PMID: 19968258]
    P388/ADR IC50
    40 1
    Compound: Daunorubicin
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM verapamil by ELISA
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM verapamil by ELISA
    		[PMID: 17154505]
    K562 IC50
    0.141 3
    Compound: 15
    Cytotoxicity against human K562 cells incubated for 2 hrs by cell titre blue viability assay
    Cytotoxicity against human K562 cells incubated for 2 hrs by cell titre blue viability assay
    		[PMID: 37561481]
    MDA-MB-231 IC50
    0.091 3
    Compound: Daunorubicin
    Antiproliferative activity against human MDA-MB-231 cells by XTT assay
    Antiproliferative activity against human MDA-MB-231 cells by XTT assay
    		[PMID: 25467291]
    PANC-1 IC50
    466.7 1
    Compound: Dau
    Cytostatic activity against human PANC1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human PANC1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    MDA-MB-435 IC50
    79 1
    Compound: Daunorubicin
    Antiproliferative activity against MDA435/LCC6 cells by ELISA
    Antiproliferative activity against MDA435/LCC6 cells by ELISA
    		[PMID: 17154505]
    K562 IC50
    0.141 3
    Compound: 3
    Cytotoxicity against human K562 cells incubated for 2 hrs followed by compound washout and measured after 72 hrs by Celltiter-blue viability assay
    Cytotoxicity against human K562 cells incubated for 2 hrs followed by compound washout and measured after 72 hrs by Celltiter-blue viability assay
    		[PMID: 39088428]
    PC-3 IC50
    26 1
    Compound: Dau
    Cytostatic activity against human PC3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human PC3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    K562 IC50
    0.286 3
    Compound: 3
    Cytotoxicity against human K562 cells overexpressing ABCG2 incubated for 2 hrs followed by compound washout and measured after 72 hrs by Celltiter-blue viability assay
    Cytotoxicity against human K562 cells overexpressing ABCG2 incubated for 2 hrs followed by compound washout and measured after 72 hrs by Celltiter-blue viability assay
    		[PMID: 39088428]
    RD IC50
    2.45 3
    Compound: Daunorubicin
    Cytotoxicity in human RD cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human RD cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    Jurkat IC50
    82.6 1
    Compound: Daunorubicin
    Cytotoxicity against Jurkat T lymphocytes by MTT assay
    Cytotoxicity against Jurkat T lymphocytes by MTT assay
    		[PMID: 16366602]
    MEL-JUSO IC50
    0.286 3
    Compound: 15
    Cytotoxicity against human MEL-JUSO cells incubated for 2 hrs by cell titre blue viability assay
    Cytotoxicity against human MEL-JUSO cells incubated for 2 hrs by cell titre blue viability assay
    		[PMID: 37561481]
    K562 IC50
    0.45 6
    Compound: daunorubicin
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    RD IC50
    2.45 3
    Compound: Daunorubicin
    Antiproliferative activity against human RD cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human RD cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    MES-SA IC50
    0.07 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the human uterine sarcoma cell line MES-SA
    In vitro cytotoxic activity was evaluated using the human uterine sarcoma cell line MES-SA
    		[PMID: 12443763]
    K562 IC50
    0.686 3
    Compound: 3
    Cytotoxicity against human K562 cells overexpressing ABCB1 incubated for 2 hrs followed by compound washout and measured after 72 hrs by Celltiter-blue viability assay
    Cytotoxicity against human K562 cells overexpressing ABCB1 incubated for 2 hrs followed by compound washout and measured after 72 hrs by Celltiter-blue viability assay
    		[PMID: 39088428]
    SF-268 GI50
    0.6 3
    Compound: DAR
    Cytotoxicity against human SF268 cells after 72 hrs by XTT assay
    Cytotoxicity against human SF268 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    K562 IC50
    1.49 6
    Compound: Daunorubicin
    Cytotoxicity against human K562 cells after 6 hrs by MTT assay
    Cytotoxicity against human K562 cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    SK-MES-1 IC50
    0.17 3
    Compound: DAU
    Antiproliferative activity against human SKMES1 cells after 72 hrs by MTS assay
    Antiproliferative activity against human SKMES1 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    MES-SA IC50
    3 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the MES-SA multidrug-resistant subline MES-SA/Dx5
    In vitro cytotoxic activity was evaluated using the MES-SA multidrug-resistant subline MES-SA/Dx5
    		[PMID: 12443763]
    MES-SA IC50
    0.021 3
    Compound: DNR
    The compound was evaluated for the growth inhibition of MES-SA uterine tumor cell lines using MTT assay.
    The compound was evaluated for the growth inhibition of MES-SA uterine tumor cell lines using MTT assay.
    		[PMID: 10698449]
    K562 IC50
    13.3 3
    Compound: Daunorubicin
    Antiproliferative activity against human K562 cells by WST-8 assay
    Antiproliferative activity against human K562 cells by WST-8 assay
    		[PMID: 38408511]
    SK-OV-3 IC50
    20.6 3
    Compound: DNR
    Cytotoxicity against human SKOV3 cells after 24 hrs by XTT assay
    Cytotoxicity against human SKOV3 cells after 24 hrs by XTT assay
    		[PMID: 24900668]
    MES-SA/Dx5 IC50
    2 3
    Compound: DNR
    The compound was evaluated for the growth inhibition of Dx5 cell lines using MTT assay.
    The compound was evaluated for the growth inhibition of Dx5 cell lines using MTT assay.
    		[PMID: 10698449]
    K562 IC50
    15 1
    Compound: DNR
    Cytotoxicity against K562 cells by MTS
    Cytotoxicity against K562 cells by MTS
    		[PMID: 16451059]
    THP-1 IC50
    26.9 3
    Compound: DNM
    Cytotoxicity against PMA-stimulated human THP1 cells after 72 hrs by MTT assay
    Cytotoxicity against PMA-stimulated human THP1 cells after 72 hrs by MTT assay
    		[PMID: 22939695]
    K562 IC50
    15.2 6
    Compound: daunorubicin
    Cytotoxicity against human doxorubicin-resistant K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human doxorubicin-resistant K562 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    MES-SA/Dx5 IC50
    0.014 3
    Compound: DNR
    The compound was evaluated for the growth inhibition of Dx5 w/PSC cell lines using MTT assay.
    The compound was evaluated for the growth inhibition of Dx5 w/PSC cell lines using MTT assay.
    		[PMID: 10698449]
    U-87MG ATCC IC50
    27.9 1
    Compound: Dau
    Cytostatic activity against human U87 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human U87 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    K562 IC50
    8.5 6
    Compound: Daunorubicin
    Cytotoxicity against human doxorubicin-resistant K562 cells after 6 hrs by MTT assay
    Cytotoxicity against human doxorubicin-resistant K562 cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    NCI-H69 IC50
    100 1
    Compound: daunorubicin
    Antiproliferative activity against drug sensitive NCI-H69 cell line by Alamar Blue assay
    Antiproliferative activity against drug sensitive NCI-H69 cell line by Alamar Blue assay
    		[PMID: 17286393]
    Vero IC50
    2.5 3
    Compound: Dauno
    Cytotoxicity against african green monkey Vero cells after 3 days by MTS assay
    Cytotoxicity against african green monkey Vero cells after 3 days by MTS assay
    		[PMID: 21094049]
    P388/ADR IC50
    106 1
    Compound: Daunorubicin
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    		[PMID: 17154505]
    K562 IC50
    > 5 3
    Compound: DNR
    Cytotoxicity against Dox-resistant K562 cells by MTS
    Cytotoxicity against Dox-resistant K562 cells by MTS
    		[PMID: 16451059]
    WiDr IC50
    240.1 1
    Compound: Dau
    Cytostatic activity against human WiDr cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human WiDr cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    MRC5 IC50
    0.88 3
    Compound: DAR
    Antiproliferative activity against human MRC5 cells
    Antiproliferative activity against human MRC5 cells
    		[PMID: 21599000]
    MRC5 IC50
    0.078 3
    Compound: Daunorubicin
    Antiproliferative activity against human MRC5 cells by XTT assay
    Antiproliferative activity against human MRC5 cells by XTT assay
    		[PMID: 25467291]
    CT26.WT IC50
    126 1
    Compound: Dau
    Cytostatic activity against mouse CT26.WT cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against mouse CT26.WT cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    KB IC50
    0.22 6
    Compound: daunorubicin
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    HCT-116 IC50
    127.1 1
    Compound: Dau
    Cytostatic activity against human HCT116 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human HCT116 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    KB IC50
    0.45 6
    Compound: Daunorubicin
    Cytotoxicity against human KB cells after 6 hrs by MTT assay
    Cytotoxicity against human KB cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    MDA-MB-435 IC50
    129 1
    Compound: Daunorubicin
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    		[PMID: 17154505]
    KB IC50
    0.64 3
    Compound: Daunorubicin
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    		[PMID: 20363142]
    HT-29 IC50
    133 1
    Compound: Daunomycin
    Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay
    		[PMID: 2778449]
    KB IC50
    2.07 3
    Compound: DNR
    In vitro cytotoxicity using human epidermoid carcinoma (KB-A1) cells
    In vitro cytotoxicity using human epidermoid carcinoma (KB-A1) cells
    		10.1016/0960-894X(96)00457-X
    PC-3 IC50
    170.1 1
    Compound: 1a; DNR
    Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
    Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
    		[PMID: 38412432]
    KB IC50
    2.07 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the KB-3-1 resistant to adriamycin (ADR) subline KB-A1
    In vitro cytotoxic activity was evaluated using the KB-3-1 resistant to adriamycin (ADR) subline KB-A1
    		[PMID: 12443763]
    A549 IC50
    199 1
    Compound: 1a; DNR
    Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
    		[PMID: 38412432]
    KB 3-1 IC50
    0.007 3
    Compound: DNR
    In vitro cytotoxicity using human epidermoid carcinoma (KB-3-1) cells
    In vitro cytotoxicity using human epidermoid carcinoma (KB-3-1) cells
    		10.1016/0960-894X(96)00457-X
    NCI/ADR-RES IC50
    51.62 3
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7/ADR cells incubated for 48 hrs by CCK-8 assay
    Antiproliferative activity against human MCF7/ADR cells incubated for 48 hrs by CCK-8 assay
    		[PMID: 33725657]
    KB 3-1 IC50
    0.007 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the human epidermoid carcinoma cell line KB-3-1
    In vitro cytotoxic activity was evaluated using the human epidermoid carcinoma cell line KB-3-1
    		[PMID: 12443763]
    NCI/ADR-RES IC50
    7.12 3
    Compound: Daunomycin
    Growth inhibition of human MCF7/ADR cells after 48 hrs by SRB assay
    Growth inhibition of human MCF7/ADR cells after 48 hrs by SRB assay
    		[PMID: 28246041]
    HT-29 IC50
    202.9 1
    Compound: Dau
    Cytostatic activity against human HT-29 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human HT-29 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    NCI-H1299 IC50
    0.096 3
    Compound: Daunorubicin
    Antiproliferative activity against human H1299 cells by XTT assay
    Antiproliferative activity against human H1299 cells by XTT assay
    		[PMID: 25467291]
    L1210 ED50
    0.23 3
    Compound: 1
    Inhibition of RNA synthesis in mouse L1210 cells
    Inhibition of RNA synthesis in mouse L1210 cells
    		[PMID: 690999]
    WiDr IC50
    240.1 1
    Compound: Dau
    Cytostatic activity against human WiDr cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human WiDr cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    L1210 ED50
    0.3 3
    Compound: Daunomycin
    Inhibition of DNA synthesis in mouse L1210 cells preincubated for 3 hrs followed by [3H]-thymidine addition measured after 1 hr by scintillation spectrometric analysis
    Inhibition of DNA synthesis in mouse L1210 cells preincubated for 3 hrs followed by [3H]-thymidine addition measured after 1 hr by scintillation spectrometric analysis
    		[PMID: 176359]
    L1210 ED50
    0.3 3
    Compound: Daunomycin
    Inhibition of RNA synthesis in mouse L1210 cells preincubated for 3 hrs followed by [3H]-uridine addition measured after 1 hr by scintillation spectrometric analysis
    Inhibition of RNA synthesis in mouse L1210 cells preincubated for 3 hrs followed by [3H]-uridine addition measured after 1 hr by scintillation spectrometric analysis
    		[PMID: 176359]
    NCI-H460 GI50
    0.38 3
    Compound: DAR
    Cytotoxicity against human NCI-H460 cells after 72 hrs by XTT assay
    Cytotoxicity against human NCI-H460 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    L1210 ED50
    0.33 3
    Compound: 1
    Compound was evaluated for the 50% inhibition of the incorporation of [3H]- thymidine in the RNA (inhibition of synthesis in leukemia L1210 cells)
    Compound was evaluated for the 50% inhibition of the incorporation of [3H]- thymidine in the RNA (inhibition of synthesis in leukemia L1210 cells)
    		[PMID: 3761325]
    NCI-H460 IC50
    0.38 3
    Compound: DAR
    Anticancer activity against human NCI-H460 cells
    Anticancer activity against human NCI-H460 cells
    		[PMID: 21599000]
    MRC5 IC50
    254.7 1
    Compound: Dau
    Cytostatic activity against human MRC5 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human MRC5 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    L1210 ED50
    0.33 3
    Compound: 1
    Inhibition of RNA synthesis in mouse L1210 cells
    Inhibition of RNA synthesis in mouse L1210 cells
    		[PMID: 423182]
    L1210 ED50
    0.33 3
    Compound: 1
    Inhibition of RNA synthesis in mouse L1210 cells
    Inhibition of RNA synthesis in mouse L1210 cells
    		[PMID: 490536]
    MCF7 IC50
    286 1
    Compound: Dau
    Cytostatic activity against human MCF7 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human MCF7 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    NIH3T3 IC50
    1.8 3
    Compound: Dauno
    Cytotoxicity against mouse NIH/3T3 cells after 3 days by MTS assay
    Cytotoxicity against mouse NIH/3T3 cells after 3 days by MTS assay
    		[PMID: 21094049]
    L1210 ED50
    0.33 3
    Compound: 2
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated uridine in the RNA of actively growing L1210 cells.
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated uridine in the RNA of actively growing L1210 cells.
    		[PMID: 7086816]
    NIH3T3 IC50
    1.01 3
    Compound: Dounorubicin
    Intrinsic cytotoxicity against mouse NIH/3T3 cells overexpressing MDR1 after 72 hrs by MTT assay
    Intrinsic cytotoxicity against mouse NIH/3T3 cells overexpressing MDR1 after 72 hrs by MTT assay
    		[PMID: 18954040]
    L1210 ED50
    0.48 3
    Compound: 1
    Inhibition of DNA synthesis in mouse L1210 cells
    Inhibition of DNA synthesis in mouse L1210 cells
    		[PMID: 690999]
    NIH3T3 IC50
    0.044 3
    Compound: Dounorubicin
    Intrinsic cytotoxicity against wild type mouse NIH/3T3 cells after 72 hrs by MTT assay
    Intrinsic cytotoxicity against wild type mouse NIH/3T3 cells after 72 hrs by MTT assay
    		[PMID: 18954040]
    L1210 ED50
    0.66 3
    Compound: 1
    Compound was evaluated for the 50% inhibition of the incorporation of [3H]- thymidine in the DNA (inhibition of synthesis in leukemia L1210 cells)
    Compound was evaluated for the 50% inhibition of the incorporation of [3H]- thymidine in the DNA (inhibition of synthesis in leukemia L1210 cells)
    		[PMID: 3761325]
    PANC-1 IC50
    466.7 1
    Compound: Dau
    Cytostatic activity against human PANC1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human PANC1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    L1210 ED50
    0.66 3
    Compound: 1
    Inhibition of DNA synthesis in mouse L1210 cells
    Inhibition of DNA synthesis in mouse L1210 cells
    		[PMID: 423182]
    OVCAR-3 IC50
    472.9 1
    Compound: Dau
    Cytostatic activity against human OVCAR3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human OVCAR3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    L1210 ED50
    0.66 3
    Compound: 1
    Inhibition of DNA synthesis in mouse L1210 cells
    Inhibition of DNA synthesis in mouse L1210 cells
    		[PMID: 490536]
    L1210 ED50
    0.66 3
    Compound: 2
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated thymidine in the DNA of actively growing L1210 cells
    Concentration of drug necessary to reduce by 50% the incorporation of tritiated thymidine in the DNA of actively growing L1210 cells
    		[PMID: 7086816]
    RD IC50
    2.45 3
    Compound: Daunorubicin
    Antiproliferative activity against human RD cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human RD cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    RD IC50
    2.45 3
    Compound: Daunorubicin
    Cytotoxicity in human RD cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human RD cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    L1210 IC50
    0.03 3
    Compound: Daunorubicin
    Inhibitory activity was measured against murine L1210 leukemia cells.
    Inhibitory activity was measured against murine L1210 leukemia cells.
    		[PMID: 9733483]
    L1210 IC50
    0.033 3
    Compound: DNR
    In vitro cytotoxicity using murine leukemia L1210 cells from american type culture collection.
    In vitro cytotoxicity using murine leukemia L1210 cells from american type culture collection.
    		10.1016/0960-894X(96)00457-X
    SF-268 GI50
    0.6 3
    Compound: DAR
    Cytotoxicity against human SF268 cells after 72 hrs by XTT assay
    Cytotoxicity against human SF268 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    SF-268 IC50
    0.6 3
    Compound: DAR
    Anticancer activity against human SF268 cells
    Anticancer activity against human SF268 cells
    		[PMID: 21599000]
    L1210 IC50
    0.04 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the murine leukemia L1210 cell line
    In vitro cytotoxic activity was evaluated using the murine leukemia L1210 cell line
    		[PMID: 12443763]
    MDA-MB-435 IC50
    977 1
    Compound: Daunorubicin
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells by ELISA
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells by ELISA
    		[PMID: 17154505]
    P388/ADR IC50
    2111 1
    Compound: Daunorubicin
    Antiproliferative activity against adriamycin resistant P388 cells by ELISA
    Antiproliferative activity against adriamycin resistant P388 cells by ELISA
    		[PMID: 17154505]
    SK-MES-1 IC50
    0.17 3
    Compound: DAU
    Antiproliferative activity against human SKMES1 cells after 72 hrs by MTS assay
    Antiproliferative activity against human SKMES1 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    SK-OV-3 IC50
    20.6 3
    Compound: DNR
    Cytotoxicity against human SKOV3 cells after 24 hrs by XTT assay
    Cytotoxicity against human SKOV3 cells after 24 hrs by XTT assay
    		[PMID: 24900668]
    THP-1 IC50
    26.9 3
    Compound: DNM
    Cytotoxicity against PMA-stimulated human THP1 cells after 72 hrs by MTT assay
    Cytotoxicity against PMA-stimulated human THP1 cells after 72 hrs by MTT assay
    		[PMID: 22939695]
    U2OS IC50
    0.061 3
    Compound: 15
    Cytotoxicity against human U2OS cells incubated for 2 hrs by cell titre blue viability assay
    Cytotoxicity against human U2OS cells incubated for 2 hrs by cell titre blue viability assay
    		[PMID: 37561481]
    HCT-15 IC50
    >400 1
    Compound: daunorubicin
    Antiproliferative activity against drug resistant HCT15 cell line expressing MDR1 by Alamar Blue assay
    Antiproliferative activity against drug resistant HCT15 cell line expressing MDR1 by Alamar Blue assay
    		[PMID: 17286393]
    MES-SA/Dx5 IC50
    >400 1
    Compound: daunorubicin
    Antiproliferative activity against drug resistant Messa/DX5 cell line expressing MDR1 by Alamar Blue assay
    Antiproliferative activity against drug resistant Messa/DX5 cell line expressing MDR1 by Alamar Blue assay
    		[PMID: 17286393]
    Vero IC50
    2.5 3
    Compound: Dauno
    Cytotoxicity against african green monkey Vero cells after 3 days by MTS assay
    Cytotoxicity against african green monkey Vero cells after 3 days by MTS assay
    		[PMID: 21094049]
    YOSHIDA IC50
    <0.02 3
    Compound: Daunomycin
    Concentration inhibiting [3H]TdR incorporation in Yoshida sarcoma tumor cells in vitro in rats
    Concentration inhibiting [3H]TdR incorporation in Yoshida sarcoma tumor cells in vitro in rats
    		[PMID: 1322986]
    L5178Y IC50
    0.3 3
    Compound: liposomal daunorubicin, DaunoXome
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    		[PMID: 23199479]
    L5178Y IC50
    0.73 3
    Compound: Daunorubicin
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells after 24 hrs by MTT assay
    		[PMID: 23199479]
    L5178Y IC50
    2.32 3
    Compound: liposomal daunorubicin, DaunoXome
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    		[PMID: 23199479]
    L5178Y IC50
    7.73 3
    Compound: Daunorubicin
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    Cytotoxicity against mouse L5178Y cells expressing p-gp after 24 hrs by MTT assay
    		[PMID: 23199479]
    LNCaP IC50
    0.1 3
    Compound: Dau, daunomycin
    Cytostatic activity against human LNCAP cells after 4 days by MTT assay
    Cytostatic activity against human LNCAP cells after 4 days by MTT assay
    		[PMID: 22480495]
    MCF7 GI50
    0.86 3
    Compound: DAR
    Cytotoxicity against human MCF7 cells after 72 hrs by XTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    MCF7 IC50
    0.033 6
    Compound: Daunorubicin
    Cytotoxicity against human MCF7 cells after 6 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 6 hrs by MTT assay
    		[PMID: 21493075]
    MCF7 IC50
    0.33 6
    Compound: daunorubicin
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 19606850]
    MCF7 IC50
    0.4 3
    Compound: Dau, daunomycin
    Cytostatic activity against human MCF7 cells after 4 days by MTT assay
    Cytostatic activity against human MCF7 cells after 4 days by MTT assay
    		[PMID: 22480495]
    MCF7 IC50
    0.56 3
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    MCF7 IC50
    0.5 6
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    		[PMID: 21109433]
    MCF7 IC50
    0.65 3
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7 cells by XTT assay
    Antiproliferative activity against human MCF7 cells by XTT assay
    		[PMID: 25467291]
    MCF7 IC50
    0.95 3
    Compound: DAU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    MCF7 IC50
    0.98 3
    Compound: Daunorubicin
    Antitumor activity against human MCF7 cells incubated for 48 hrs by CCK8 assay
    Antitumor activity against human MCF7 cells incubated for 48 hrs by CCK8 assay
    		[PMID: 37229830]
    MCF7 IC50
    1.44 3
    Compound: Daunorubicin
    Cytotoxicity in human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    MCF7 IC50
    286 1
    Compound: Dau
    Cytostatic activity against human MCF7 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human MCF7 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    MCF7 IC50
    33.9 3
    Compound: DNR
    Cytotoxicity against human MCF7 cells after 24 hrs by XTT assay
    Cytotoxicity against human MCF7 cells after 24 hrs by XTT assay
    		[PMID: 24900668]
    MCF7 IC50
    39 1
    Compound: Daunomycin
    Evaluated in vitro for antiproliferative activity against MCF-7 cell lines model of hormone dependent breast cancer
    Evaluated in vitro for antiproliferative activity against MCF-7 cell lines model of hormone dependent breast cancer
    		10.1016/S0960-894X(97)10152-4
    MCF7 IC50
    5.03 3
    Compound: DAR
    Anticancer activity against human MCF7 cells
    Anticancer activity against human MCF7 cells
    		[PMID: 21599000]
    MCF7 IC50
    5.5 3
    Compound: Dauno
    Cytotoxicity against human MCF7 cells after 24 hrs by MTS assay
    Cytotoxicity against human MCF7 cells after 24 hrs by MTS assay
    		[PMID: 21094049]
    MCF7 IC50
    60 101
    Compound: daunorubicin
    compound was tested in vitro for inhibition activity against a sensitive human breast carcinoma line cells.
    compound was tested in vitro for inhibition activity against a sensitive human breast carcinoma line cells.
    		[PMID: 9258351]
    MCF7 IC50
    60 101
    Compound: daunorubicin
    Compound was tested for its toxicity against human breast cancer cells(MCF-7)
    Compound was tested for its toxicity against human breast cancer cells(MCF-7)
    		[PMID: 9548820]
    MDA-MB-231 GI50
    0.02 3
    Compound: daunorubicin
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay
    		[PMID: 19968258]
    MDA-MB-231 IC50
    0.091 3
    Compound: Daunorubicin
    Antiproliferative activity against human MDA-MB-231 cells by XTT assay
    Antiproliferative activity against human MDA-MB-231 cells by XTT assay
    		[PMID: 25467291]
    MDA-MB-231 IC50
    52.9 1
    Compound: Dau
    Cytostatic activity against human MDA-MB-231 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human MDA-MB-231 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    MDA-MB-361 IC50
    17 1
    Compound: Dauno
    The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) expressing LacZ (beta-galactosidase).
    The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) expressing LacZ (beta-galactosidase).
    		[PMID: 10395490]
    MDA-MB-361 IC50
    21 1
    Compound: Dauno
    The compound was tested for extracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of stCPG2 prodrug
    The compound was tested for extracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of stCPG2 prodrug
    		[PMID: 10395490]
    MDA-MB-361 IC50
    36 1
    Compound: Dauno
    The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of CPG2 prodrug
    The compound was tested for intracellular cytotoxicity against MDA MB 361(mammary carcinoma cell line) in the presence of CPG2 prodrug
    		[PMID: 10395490]
    MDA-MB-435 IC50
    129 1
    Compound: Daunorubicin
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    		[PMID: 17154505]
    MDA-MB-435 IC50
    79 1
    Compound: Daunorubicin
    Antiproliferative activity against MDA435/LCC6 cells by ELISA
    Antiproliferative activity against MDA435/LCC6 cells by ELISA
    		[PMID: 17154505]
    MDA-MB-435 IC50
    977 1
    Compound: Daunorubicin
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells by ELISA
    Antiproliferative activity against multidrug resistant MDA435/LCC6 cells by ELISA
    		[PMID: 17154505]
    MEL-JUSO IC50
    0.286 3
    Compound: 15
    Cytotoxicity against human MEL-JUSO cells incubated for 2 hrs by cell titre blue viability assay
    Cytotoxicity against human MEL-JUSO cells incubated for 2 hrs by cell titre blue viability assay
    		[PMID: 37561481]
    MES-SA IC50
    0.021 3
    Compound: DNR
    The compound was evaluated for the growth inhibition of MES-SA uterine tumor cell lines using MTT assay.
    The compound was evaluated for the growth inhibition of MES-SA uterine tumor cell lines using MTT assay.
    		[PMID: 10698449]
    MES-SA IC50
    0.07 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the human uterine sarcoma cell line MES-SA
    In vitro cytotoxic activity was evaluated using the human uterine sarcoma cell line MES-SA
    		[PMID: 12443763]
    MES-SA IC50
    20 1
    Compound: daunorubicin
    Antiproliferative activity against drug sensitive Messa cell line by Alamar Blue assay
    Antiproliferative activity against drug sensitive Messa cell line by Alamar Blue assay
    		[PMID: 17286393]
    MES-SA IC50
    3 3
    Compound: Daunomycin (DNR)
    In vitro cytotoxic activity was evaluated using the MES-SA multidrug-resistant subline MES-SA/Dx5
    In vitro cytotoxic activity was evaluated using the MES-SA multidrug-resistant subline MES-SA/Dx5
    		[PMID: 12443763]
    MES-SA/Dx5 IC50
    0.014 3
    Compound: DNR
    The compound was evaluated for the growth inhibition of Dx5 w/PSC cell lines using MTT assay.
    The compound was evaluated for the growth inhibition of Dx5 w/PSC cell lines using MTT assay.
    		[PMID: 10698449]
    MES-SA/Dx5 IC50
    2 3
    Compound: DNR
    The compound was evaluated for the growth inhibition of Dx5 cell lines using MTT assay.
    The compound was evaluated for the growth inhibition of Dx5 cell lines using MTT assay.
    		[PMID: 10698449]
    MES-SA/Dx5 IC50
    > 400 1
    Compound: daunorubicin
    Antiproliferative activity against drug resistant Messa/DX5 cell line expressing MDR1 by Alamar Blue assay
    Antiproliferative activity against drug resistant Messa/DX5 cell line expressing MDR1 by Alamar Blue assay
    		[PMID: 17286393]
    MRC5 IC50
    0.078 3
    Compound: Daunorubicin
    Antiproliferative activity against human MRC5 cells by XTT assay
    Antiproliferative activity against human MRC5 cells by XTT assay
    		[PMID: 25467291]
    MRC5 IC50
    0.88 3
    Compound: DAR
    Antiproliferative activity against human MRC5 cells
    Antiproliferative activity against human MRC5 cells
    		[PMID: 21599000]
    MRC5 IC50
    254.7 1
    Compound: Dau
    Cytostatic activity against human MRC5 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human MRC5 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    NCI-H1299 IC50
    0.096 3
    Compound: Daunorubicin
    Antiproliferative activity against human H1299 cells by XTT assay
    Antiproliferative activity against human H1299 cells by XTT assay
    		[PMID: 25467291]
    NCI-H1650 IC50
    47.5 1
    Compound: Dau
    Cytostatic activity against human NCI-H1650 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human NCI-H1650 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    NCI-H1975 IC50
    13.3 1
    Compound: Dau
    Cytostatic activity against human NCI-H1975 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human NCI-H1975 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    NCI-H460 GI50
    0.38 3
    Compound: DAR
    Cytotoxicity against human NCI-H460 cells after 72 hrs by XTT assay
    Cytotoxicity against human NCI-H460 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    NCI-H460 IC50
    0.38 3
    Compound: DAR
    Anticancer activity against human NCI-H460 cells
    Anticancer activity against human NCI-H460 cells
    		[PMID: 21599000]
    NCI-H460 IC50
    3.5 1
    Compound: Daunomycin
    Evaluated in vitro for antiproliferative activity against NIC-H460 cell lines derived from large cell carcinoma of the lung
    Evaluated in vitro for antiproliferative activity against NIC-H460 cell lines derived from large cell carcinoma of the lung
    		10.1016/S0960-894X(97)10152-4
    NCI-H69 IC50
    100 1
    Compound: daunorubicin
    Antiproliferative activity against drug sensitive NCI-H69 cell line by Alamar Blue assay
    Antiproliferative activity against drug sensitive NCI-H69 cell line by Alamar Blue assay
    		[PMID: 17286393]
    NCI/ADR-RES IC50
    2000 101
    Compound: daunorubicin
    compound was tested in vitro for inhibition activity against doxorubicin resistant counterpart of human breast carcinoma line cells.
    compound was tested in vitro for inhibition activity against doxorubicin resistant counterpart of human breast carcinoma line cells.
    		[PMID: 9258351]
    NCI/ADR-RES IC50
    2000 101
    Compound: daunorubicin
    Compound was tested for its toxicity against doxorubicin resistant human breast cancer cells (MCF-7/ADR).
    Compound was tested for its toxicity against doxorubicin resistant human breast cancer cells (MCF-7/ADR).
    		[PMID: 9548820]
    NCI/ADR-RES IC50
    51.62 3
    Compound: Daunorubicin
    Antiproliferative activity against human MCF7/ADR cells incubated for 48 hrs by CCK-8 assay
    Antiproliferative activity against human MCF7/ADR cells incubated for 48 hrs by CCK-8 assay
    		[PMID: 33725657]
    NCI/ADR-RES IC50
    51.62 3
    Compound: Daunorubicin
    Antitumor activity against human MCF7ADR cells incubated for 48 hrs by CCK8 assay
    Antitumor activity against human MCF7ADR cells incubated for 48 hrs by CCK8 assay
    		[PMID: 37229830]
    NCI/ADR-RES IC50
    7.12 3
    Compound: Daunomycin
    Growth inhibition of human MCF7/ADR cells after 48 hrs by SRB assay
    Growth inhibition of human MCF7/ADR cells after 48 hrs by SRB assay
    		[PMID: 28246041]
    NIH3T3 IC50
    0.044 3
    Compound: Dounorubicin
    Intrinsic cytotoxicity against wild type mouse NIH/3T3 cells after 72 hrs by MTT assay
    Intrinsic cytotoxicity against wild type mouse NIH/3T3 cells after 72 hrs by MTT assay
    		[PMID: 18954040]
    NIH3T3 IC50
    1.01 3
    Compound: Dounorubicin
    Intrinsic cytotoxicity against mouse NIH/3T3 cells overexpressing MDR1 after 72 hrs by MTT assay
    Intrinsic cytotoxicity against mouse NIH/3T3 cells overexpressing MDR1 after 72 hrs by MTT assay
    		[PMID: 18954040]
    NIH3T3 IC50
    1.8 3
    Compound: Dauno
    Cytotoxicity against mouse NIH/3T3 cells after 3 days by MTS assay
    Cytotoxicity against mouse NIH/3T3 cells after 3 days by MTS assay
    		[PMID: 21094049]
    NSCLC IC50
    3.9 1
    Compound: Daunomycin
    Evaluated in vitro for antiproliferative activity against NYH cell lines derived from small cell lung cancer
    Evaluated in vitro for antiproliferative activity against NYH cell lines derived from small cell lung cancer
    		10.1016/S0960-894X(97)10152-4
    OVCAR-3 IC50
    472.9 1
    Compound: Dau
    Cytostatic activity against human OVCAR3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human OVCAR3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    P388 IC50
    25 1
    Compound: Daunorubicin
    Antiproliferative activity against P388 cells by ELISA
    Antiproliferative activity against P388 cells by ELISA
    		[PMID: 17154505]
    P388 IC50
    28 1
    Compound: Daunomycin
    Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay
    Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay
    		[PMID: 2778449]
    P388 IC50
    3 1
    Compound: DNR
    Compound was evaluated for cytotoxicity against P388 leukemia cell line.
    Compound was evaluated for cytotoxicity against P388 leukemia cell line.
    		[PMID: 10479297]
    P388/ADR IC50
    106 1
    Compound: Daunorubicin
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM 1,13-bis[4'-((5,7-dihydroxy)-4H-chromen-4-on-2-yl)phenyl]-1,4,7,10,13-pentaoxatridecane by ELISA
    		[PMID: 17154505]
    P388/ADR IC50
    2111 1
    Compound: Daunorubicin
    Antiproliferative activity against adriamycin resistant P388 cells by ELISA
    Antiproliferative activity against adriamycin resistant P388 cells by ELISA
    		[PMID: 17154505]
    P388/ADR IC50
    40 1
    Compound: Daunorubicin
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM verapamil by ELISA
    Antiproliferative activity against adriamycin resistant P388 cells in presence of 5 uM verapamil by ELISA
    		[PMID: 17154505]
    PANC-1 IC50
    466.7 1
    Compound: Dau
    Cytostatic activity against human PANC1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human PANC1 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    PC-3 IC50
    170.1 1
    Compound: 1a; DNR
    Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
    Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
    		[PMID: 38412432]
    PC-3 IC50
    26 1
    Compound: Dau
    Cytostatic activity against human PC3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human PC3 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    RD IC50
    2.45 3
    Compound: Daunorubicin
    Cytotoxicity in human RD cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity in human RD cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    		[PMID: 28923382]
    RD IC50
    2.45 3
    Compound: Daunorubicin
    Antiproliferative activity against human RD cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human RD cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    		[PMID: 31431363]
    SF-268 GI50
    0.6 3
    Compound: DAR
    Cytotoxicity against human SF268 cells after 72 hrs by XTT assay
    Cytotoxicity against human SF268 cells after 72 hrs by XTT assay
    		[PMID: 20591678]
    SF-268 IC50
    0.6 3
    Compound: DAR
    Anticancer activity against human SF268 cells
    Anticancer activity against human SF268 cells
    		[PMID: 21599000]
    SK-MES-1 IC50
    0.17 3
    Compound: DAU
    Antiproliferative activity against human SKMES1 cells after 72 hrs by MTS assay
    Antiproliferative activity against human SKMES1 cells after 72 hrs by MTS assay
    		[PMID: 22260166]
    SK-OV-3 IC50
    20.6 3
    Compound: DNR
    Cytotoxicity against human SKOV3 cells after 24 hrs by XTT assay
    Cytotoxicity against human SKOV3 cells after 24 hrs by XTT assay
    		[PMID: 24900668]
    THP-1 IC50
    26.9 3
    Compound: DNM
    Cytotoxicity against PMA-stimulated human THP1 cells after 72 hrs by MTT assay
    Cytotoxicity against PMA-stimulated human THP1 cells after 72 hrs by MTT assay
    		[PMID: 22939695]
    U-87MG ATCC IC50
    27.9 1
    Compound: Dau
    Cytostatic activity against human U87 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human U87 cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    U2OS IC50
    0.061 3
    Compound: 15
    Cytotoxicity against human U2OS cells incubated for 2 hrs by cell titre blue viability assay
    Cytotoxicity against human U2OS cells incubated for 2 hrs by cell titre blue viability assay
    		[PMID: 37561481]
    Vero IC50
    2.5 3
    Compound: Dauno
    Cytotoxicity against african green monkey Vero cells after 3 days by MTS assay
    Cytotoxicity against african green monkey Vero cells after 3 days by MTS assay
    		[PMID: 21094049]
    WALKER IC50
    47 1
    Compound: Daunomycin
    In vitro antiproliferative activity against Walker cell line
    In vitro antiproliferative activity against Walker cell line
    		10.1016/S0960-894X(97)10152-4
    WiDr IC50
    240.1 1
    Compound: Dau
    Cytostatic activity against human WiDr cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    Cytostatic activity against human WiDr cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay
    		[PMID: 31100648]
    YOSHIDA IC50
    7.4 1
    Compound: Daunomycin
    In vitro antiproliferative activity against Yoshida cell lines
    In vitro antiproliferative activity against Yoshida cell lines
    		10.1016/S0960-894X(97)10152-4
    YOSHIDA IC50
    < 0.02 3
    Compound: Daunomycin
    Concentration inhibiting [3H]TdR incorporation in Yoshida sarcoma tumor cells in vitro in rats
    Concentration inhibiting [3H]TdR incorporation in Yoshida sarcoma tumor cells in vitro in rats
    		[PMID: 1322986]
    In Vitro

    Daunorubicin (0-256 μg/mL, 30 min) inhibits DNA and RNA synthesis in sensitive and resistant Ehrlich ascites tumor cells[2].
    Daunorubicin (7 nM-1.9 μM, 72 h) shows chemosensitivity in Molt-4 cells and L3.6 cells[3][4].
    Daunorubicin (0.4 μM, 48 h) induces apoptotic and necrosis in L3.6 cells[4].
    Daunorubicin (0.4 μM, 120 min) induces ROS generation in L3.6 cells[4].
    Daunorubicin (2 μM, 24 h) induces autophagy in K562 cells (myeloid cell line)[6].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Daunorubicin Related Antibodies

    Cell Viability Assay[3][4]

    Cell Line: Molt-4 cells (a human T-lymphoblastic leukemia cell line), L3.6 cells (metastatic human pancreatic cell line)
    Concentration: 7 nM-1.9 μM
    Incubation Time: 72 h
    Result: Inhibited cell viability with IC50 values of 40 nM (Molt-4) and 400 nM (L3.6).

    Apoptosis Analysis[4]

    Cell Line: L3.6 cells
    Concentration: 0.4 μM
    Incubation Time: 24 h, 48 h
    Result: Induced necrosis without apoptosis at 24 h, induced both an apoptotic and extensive necrotic response at 48 h.

    Western Blot Analysis[6]

    Cell Line: K562 cells
    Concentration: 2 μM
    Incubation Time: 24 h
    Result: Enabled the switch of LC3-I into LC3-II, accompanied with a significant increased expression level of LC3.
    In Vivo

    Daunorubicin (intravenous injection, 3 mg/kg, three times at 48 h intervals.) produces cardiotoxicity and nephrotoxicity in rats[5].
    Daunorubicin (intraperitoneal injection, 10 mg/kg) induces sister chromatid exchanges in mice[7].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: Male Sprague-Dawley rats[5]
    Dosage: 3 mg/kg
    Administration: Intravenous injection, three times at 48 h intervals.
    Result: Caused a significant increase in MDA (malondialdehyde) level in renal tissue, accompanied by a significant reduction in total GPx activity.
    Increased urinary protein excretion, serum creatinine, and BUN level.
    Molekulargewicht

    527.52

    Formel

    C27H29NO10
    CAS. Nr.
    Appearance

    Solid

    Color

    Orange to red

    SMILES

    O=C(C(C(OC)=CC=C1)=C1C2=O)C3=C2C(O)=C(C[C@@](O)(C(C)=O)C[C@@H]4O[C@@]5([H])C[C@H](N)[C@H](O)[C@H](C)O5)C4=C3O
    Structure Classification
    Initial Source

    Streptomyces peucetius and S. peucetius subsp. caesius
    Versand

    Room temperature in continental US; may vary elsewhere.
    Speicherung
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 6 months
    -20°C 1 month
    Lösungsmittel & Löslichkeit
    In Vitro: 

    DMSO : 100 mg/mL (189.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.8957 mL 9.4783 mL 18.9566 mL
    5 mM 0.3791 mL 1.8957 mL 3.7913 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    • Molaritätsrechner

    • Verdünnungsrechner

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    Reinheit & Dokumentation
    Verweise

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO 1 mM 1.8957 mL 9.4783 mL 18.9566 mL 47.3916 mL
    5 mM 0.3791 mL 1.8957 mL 3.7913 mL 9.4783 mL
    10 mM 0.1896 mL 0.9478 mL 1.8957 mL 4.7392 mL
    15 mM 0.1264 mL 0.6319 mL 1.2638 mL 3.1594 mL
    20 mM 0.0948 mL 0.4739 mL 0.9478 mL 2.3696 mL
    25 mM 0.0758 mL 0.3791 mL 0.7583 mL 1.8957 mL
    30 mM 0.0632 mL 0.3159 mL 0.6319 mL 1.5797 mL
    40 mM 0.0474 mL 0.2370 mL 0.4739 mL 1.1848 mL
    50 mM 0.0379 mL 0.1896 mL 0.3791 mL 0.9478 mL
    60 mM 0.0316 mL 0.1580 mL 0.3159 mL 0.7899 mL
    80 mM 0.0237 mL 0.1185 mL 0.2370 mL 0.5924 mL
    100 mM 0.0190 mL 0.0948 mL 0.1896 mL 0.4739 mL
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    • Your name will appear on the site.

    Daunorubicin Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Daunorubicin20830-81-3Daunomycin RP 13057 RubidomycinRP13057RP 13057RP-13057TopoisomeraseDNA/RNA SynthesisADC PayloadAutophagyBacterialAntibioticApoptosisADC CytotoxinAnti-tumorEhrlich ascites tumorpancreatic carcinoma leukemiacytotoxinMolt-4 cellL3.6 cellK562 cellschamomileInhibitorinhibitorinhibit

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