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Results for "

endo-

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (9) Antibiotic (1) Antifolate (1) Bacterial (2) Biochemical Assay Reagents (28) Cathepsin (1) Cytochrome P450 (1) DNA/RNA Synthesis (1) Drug Intermediate (1) Drug Metabolite (1) Drug-Linker Conjugates for ADC (4) Endogenous Metabolite (9) Fluorescent Dye (6) Fungal (1) Glycosidase (6) IFNAR (1) Interleukin Related (1) Isotope-Labeled Compounds (1) Microtubule/Tubulin (1) MOFs (2) Organoid (2) Orphan Nuclear Receptor (1) Phosphodiesterase (PDE) (1) Poly(ADP-ribose) Glycohydrolase (PARG) (1) PROTAC Linkers (26) Reference Standards (2) Small Interfering RNA (siRNA) (2) STING (1) Toll-like Receptor (TLR) (1) Topoisomerase (1) Wnt (3)
By Research Areas:	Cancer (44) Infection (6) Inflammation/Immunology (4) Metabolic Disease (14)
Click Chemistry:	ADC Synthesis (6) Labeling and Fluorescence Imaging (5) PROTAC Synthesis (20) BCN (41)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

119

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12238

IWR-1 Maximum Cited Publications 61 Publications Verification endo-IWR 1; IWR-1-endo	Organoid Wnt	Inflammation/Immunology Cancer
IWR-1 (IWR-1-endo) is a tankyrase inhibitor targeting Wnt/β-catenin (IC₅₀ = 180 nM). IWR-1 compromises critical steps of the canonical Wnt signaling, namely translocation of β-catenin to the nucleus and subsequent TCF/LEF activation and expression of Wnt/β-catenin downstream targets. IWR-1 promotes β-catenin phosphorylation by promoting stability of Axin-scaffolded destruction complexes. IWR-1 can be studied in research for anti-tumor purposes, and diseases such as osteosarcoma, colorectal cancer and psoriasis .

HY-E70069

Endo S2, Streptococcus pyogenes	Others	Others
Endo-β-N-acetylglucosaminidase (Endo S2) is a key enzyme involved in the processing of free oligosaccharides in the cytosol. Endo-β-N-acetylglucosaminidase catalyzes hydrolysis of N-linked oligosaccharides .

HY-W035129

endo-BCN-NHS carbonate	Biochemical Assay Reagents	Others
endo-BCN-NHS carbonate is an elastin-like protein (ELP) modification reagent. endo-BCN-NHS carbonate can react with lysine residues in ELP to make ELP carry BCN groups, and then cross-link ELP through strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. endo-BCN-NHS carbonate promotes hydrogel formation. endo-BCN-NHS carbonate is mainly used in cell encapsulation related research .

HY-E70013

Lichenase, Microorganism endo-1,3:1,4-β-D-Glucanase	Endogenous Metabolite	Metabolic Disease
Lichenase, Microorganism (endo-1,3:1,4-β-D-Glucanase) is a specific, endo-(1-3),(1-4)-β-D-glucan 4-glucanohydrolase. Lichenase, Microorganism solubilizes β-glucans from cereal grains and gives gluco-oligosaccharides (GOS). Lichenase, Microorganism can be used in the degradation of polysaccharides in the cell walls .

HY-E70135

Endo-β-N-acetylglucosaminidase F1 endo F1	Endogenous Metabolite	Metabolic Disease
Endo-β-N-acetylglucosaminidase F1 (Endo F1) cleaves Asparagine-linked high mannose and some hybrid oligosaccharides .

HY-P3004

Endo-1,3-β-glucanase Lyticase	Endogenous Metabolite Fungal	Infection
Endo-1,3-β-glucanase (Lyticase) is an endoenzyme that can specifically cleave β-1,3-glycosidic bonds. Endo-1,3-β-glucanase recognizes and binds to β-1,3-glucan chains, catalyzing the cleavage of glycosidic bonds and hydrolyzing polysaccharides into oligosaccharides. Endo-1,3-β-glucanase eliminates vaginal Candida. Endo-1,3-β-glucanase can be used in the study of recurrent Candida vaginitis .

HY-43581

endo-BCN-O-PNB	PROTAC Linkers	Cancer
endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W111141

BCN-OH endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne	Biochemical Assay Reagents	Others
BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is an alcohol functionalized cyclooctyne derivative. BCN-OH can act as a raw material for synthesizing other probes (such as BCN-TPP). BCN-OH is used to construct targeted probes by coupling with carboxyl-containing compounds (such as TPP-COOH). BCN-OH can be used as control reagent for BCN-TPP .

HY-E70068

Endo-β-N-acetylglucosaminidase (Endo S)	Others	Others
Endo-β-N-acetylglucosaminidase (Endo S) is a family 18 glycosyl hydrolase secreted by Streptococcus pyogenes. Endo-β-N-acetylglucosaminidase (Endo S) exclusively hydrolyzes the β-1,4-di-N-acetylchitobiose core of the asparagine-linked complex-type glycan on Asn-297 of the γ-chains of IgG antibody .

HY-140069

endo-BCN-PEG4-NHS ester	PROTAC Linkers	Cancer
endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W072752

endo-BCN-PEG2-NH2	PROTAC Linkers	Cancer
endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG2-NH2 contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-141155

endo-BCN-PEG4-Val-Cit-PAB-MMAE 1 Publications Verification	Drug-Linker Conjugates for ADC	Cancer
endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable ADC linker conjugated with drug containing 4-unit PEG, which can be used for synthesizing antibody-drug conjugates (ADCs). endo-BCN-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-E70133

Endo-β-N-acetylglucosaminidase F2 endo F2	Others	Metabolic Disease
Endo-β-N-acetylglucosaminidase F2 (Endo F2), a highly specific endoglycosidase, cleaves within the chitobiose core of asparagine-linked complex biantennary and high mannose oligosaccharides from glycoproteins and glycopeptides. Endo F2 cleaves biantennary glycans at a rate approximately 20 times greater than high mannose glycans. The activity of Endo F2 is identical on biantennary structures with and without core fucosylation. Endo F2 is not active on hybrid or tri- and tetra-antennary oligosaccharides .

HY-E70134

Endo-β-N-acetylglucosaminidase F3 endo F3	Others	Metabolic Disease
Endo-β-N-acetylglucosaminidase D (Endo F3) cleaves free or Asparagine-linked triantennary oligosaccharides or α1-6 fucosylated biantennary oligosaccharides, as well as triamnnosyl chitobiose core structures .

HY-E70131

Endo H, Streptomyces picatus 1 Publications Verification endo-β-N-acetylglucosaminidase H	Others	Metabolic Disease
Endo H, Streptomyces picatus (Endo-β-N-acetylglucosaminidase H), isolated from Streptomyces plicatus, hydrolyzes the central glycosidic bond of the β1, 4-di-N-acetylchitobiose core in asparagine-linked oligosaccharides .

HY-133400

endo-BCN-PEG3-mal	PROTAC Linkers	Cancer
endo-BCN-PEG3-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG3-mal is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-E70038

Endoglycoceramidase II (EGCase II)	Endogenous Metabolite	Metabolic Disease
Endoglycoceramidase II (EGCase II) is an endo-β-glucosidase that releases intact glycans from ceramides in glycosphingolipids. Endoglycoceramidase II catalyzes the hydrolysis of β-glycosidic linkages between oligosaccharides and ceramides in various glycosphingolipids .

HY-E70573

Endo SH	Biochemical Assay Reagents	Others
Endo SH is a fusion protein of Endo S (from Streptococcus pyogenes) and Endo H (from Streptomyces plicatus), expressed in Escherichia coli. Endo SH can cleave the chitobiose core structure of high mannose, complex and some hybrid oligosaccharides in N-glycoproteins, remove N-linked high mannose in glycoproteins, and can completely replace Endo S and Endo H.

HY-W096079

*BCN-endo-PEG4-NHS*	ADC Linker	Cancer
BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-156311

*BCN-endo-PEG2-maleimide*	ADC Linker	Cancer
BCN-endo-PEG2-maleimide is an ADC Linker containing 4 PEG units. BCN-endo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

HY-157054

endo-BCN-L-Lysine	Biochemical Assay Reagents	Others
Endo-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. Endo-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W879045

Endo-BCN-PEG5-amine endo-BCN-PEG5-NH2	Biochemical Assay Reagents	Others
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-E70110

Endo-1,4-β-mannanase	Others	Others
Endo-1,4-β-mannanase is an important catalytic agent that randomly cleave the β-1,4-linkage in the mannan backbone and release short β-1,4-mannooligosaccharides and mannose .

HY-P3017

Endo-1,4-β-xylanase CtXyn11A; EC 3.2.1.8	Poly(ADP-ribose) Glycohydrolase (PARG)	Others
Endo-1,4-β-xylanase (Xylanase) is an arabinoxylan (AX) degrading enzyme and a glycoside hydrolase, is often used in biochemical studies. Endo-1,4-β-xylanase cleaves the β-xylosidic bond between two d-xylopyranosyl residues linked in β-(1,4) .

HY-140070

endo-BCN-PEG8-NHS ester	PROTAC Linkers	Cancer
endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140067

endo-BCN-PEG2-C2-NHS ester	PROTAC Linkers	Cancer
endo-BCN-PEG2-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-149618

*Cy5-PEG3-endo-BCN*	Fluorescent Dye	Others
Cy5-PEG3-endo-BCN is a derivative of the Cyanine 5 (Cy5) (HY-D0821) dye bearing 3 PEG units. Cy5-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN forms stable triazoles with azide-containing molecules under catalyst-free conditions .

HY-E70884

Endoglycosidase S2 (D184M mutant) endoS2 D184M	Glycosidase	Others
Endoglycosidase S2 (D184M mutant) (EndoS2 D184M) is a mutant endoglycosidase. Endoglycosidase S2 (D184M mutant) promotes the transfer of glyco-oxazoline donors with defined glycoforms to the Fc region of IgG antibodies .

HY-E70132

Endo-β-N-acetylglucosaminidase D endo D	Glycosidase	Metabolic Disease
Endo-β-N-acetylglucosaminidase D (Endo D), isolated from Streptococcus pneumoniae. Endo-β-N-acetylglucosaminidase D hydrolyzes Fc N-glycan of intact IgG antibodies after sequential removal of the sialic acid, galactose, and internal GlcNAc residues in the N-glycan. Endo-β-N-acetylglucosaminidase D possesses transglycosylation activity with sugar oxazoline as the donor substrate .

HY-155327B

*Cy3-PEG2-endo-BCN bromide*	Fluorescent Dye	Others
Cy3-PEG2-endo-BCN bromide is the bromide salt form of Cy3-PEG2-endo-BCN (HY-155327). Cy3-PEG2-endo-BCN bromide is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN bromide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts .

HY-135971

endo-BCN-PEG4-acid	ADC Linker	Cancer
endo-BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . endo-BCN-PEG4-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140076

endo-BCN-PEG2-alcohol	PROTAC Linkers	Cancer
endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG2-alcohol is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140073

endo-BCN-PEG4-PFP ester	PROTAC Linkers	Cancer
endo-BCN-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-PFP ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-E70070

Endo-β-N-acetylglucosaminidase (Endo A)	Bacterial	Others
Endo-β-N-acetylglucosaminidase (Endo A) is an Endo-β-N-acetylglucosaminidases (ENGases) from Arthrobacter protophormiae. Endo-β-N-acetylglucosaminidase (Endo A) can transfer a high-mannose type oligosaccharide to monosaccharides such as N-acetylglucosamine (GlcNAc) and glucose to form a new oligosaccharide. Endo-β-N-acetylglucosaminidase (Endo A) catalyzes glycopeptide synthesis by using Man3GlcNAc-oxazoline .

HY-E70069GL

Endo S2, Streptococcus pyogenes (GMP Like)	Biochemical Assay Reagents	Infection
Endo S2, Streptococcus pyogenes (GMP Like) is Endo S2, Streptococcus pyogenes (HY-E70069) produced by using GMP like guidelines. Endo-β-N-acetylglucosaminidase (Endo S2) is a key enzyme involved in the processing of free oligosaccharides in the cytosol. Endo-β-N-acetylglucosaminidase catalyzes hydrolysis of N-linked oligosaccharides .

HY-150311

endo-BCN-PEG24-NHS ester	PROTAC Linkers	Others
endo-BCN-PEG24-NHS ester is composed of a benzocyclonorbornene, a twenty-tetramer of polyethylene glycol (PEG) and an N-hydroxysuccinimide ester. endo-BCN-PEG24-NHS is utilized as linker for synthesis of PROTAC molecule .

HY-P2999

Endo-β-N-acetylglucosaminidase ENGase	Endogenous Metabolite	Others
Endo-β-N-acetylglucosaminidase (ENGase) is cytosolic deglycosylating enzyme that hydrolyzes the N-linked oligosaccharides. Endo-β-N-acetylglucosaminidase can be used for glycan analysis on glycoproteins and preparation of precursors for glycosylated compounds, is often used in biochemical studies .

HY-140072

endo-BCN-PEG2-PFP ester	PROTAC Linkers	Cancer
endo-BCN-PEG2-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG2-PFP ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140078

*bis-PEG2-endo-BCN*	ADC Linker	Cancer
bis-PEG2-endo-BCN is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . bis-PEG2-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-E70136

Endo-β-Galactosidase Keratan-sulfate endo-1,4-beta-galactosidase; Keratanase	Others	Metabolic Disease
Endo-β-Galactosidase catalyzes the hydrolysis of internal β1-4 galactose linkages in unbranched, repeating poly-N-acetyllactosamine ([GlcNAc- (1-3)Gal- (1-4)]_n) structures .

HY-E70883

Endoglycosidase S (D233Q mutant) endoS D233Q	Glycosidase	Others
Endoglycosidase S (D233Q mutant) (EndoS D233Q) is a mutant endoglycosidase, which catalyzes the glycosylation of Trastuzumab (HY-P9907)-GlcNAc with the functionalized, non-natural glycans to give glycosylated monoclonal Abs (mAbs) carrying two glycans each functionalized with two reaction handles .

HY-156317

*BCN-endo-PEG7-maleimide*	ADC Linker	Cancer
BCN-endo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-endo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-166874

*DSPE-PEG2000-endo-BCN*	Biochemical Assay Reagents	Others
DSPE-PEG2000-endo-BCN is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG2000-endo-BCN can be used in drug delivery research .

HY-401913

endo CNTinh-03	Phosphodiesterase (PDE)	Infection Cancer
Endo CNTinh-03 is inhibitor for the elevation of cAMP and cGMP induced by agonist, such as G protein-coupled receptors, adenylate cyclase, and guanylate cyclase (IC₅₀ is 4 μM). Endo CNTinh-03 inhibits cholera toxin- and Escherichia coli (STa) toxin- induced CFTR chloride current, ameliorates secretory diarrhea in mouse models, and prevents cyst growth in polycystic kidney disease model .

HY-140068

endo-BCN-PEG3-NHS ester	PROTAC Linkers	Cancer
endo-BCN-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG3-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-N8279

β-1,3-1,4-Glucanase endo-β-1,3-1,4-glucanase	Glycosidase	Metabolic Disease
β-1,3-1,4-glucanase (Endo-β-1,3-1,4-glucanase) is a glycoside hydrolase family 16 enzyme (some members belong to subfamily 25). β-1,3-1,4-glucanase shows high substrate specificity toward mixed‑linked β‑glucans and cleaves β‑1,4 glycosidic bonds adjacent to β‑1,3 linkages in an endo‑type pattern. β-1,3-1,4-glucanase can be used in industrial enzyme applications and monogastric animal feed supplementation .

HY-177684

*N-(endo-BCN-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan)*	Drug-Linker Conjugates for ADC Topoisomerase Microtubule/Tubulin	Cancer
N-(endo-BCN-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N-(endo-BCN-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.

HY-176256

endo-S-cGAFMP	STING	Cancer
endo-S-cGAFMP (Compound 3) is a STING agonist. endo-S-cGAFMP induces the production of interferon regulatory factors and proinflammatory cytokines by activating the cGAS-STING pathway, thereby enhancing innate and adaptive immune responses. endo-S-cGAFMP has potent immunostimulatory capacity in THP1 monocytes and RAW macrophages (EC₅₀ values of 2.45 μM and 5.54 μM, respectively). endo-S-cGAFMP has significant antitumor activity. endo-S-cGAFMP can be used as a potential cancer immunotherapeutic agent, especially for studies of systemic administration .

HY-N16572

*5-endo-Hydroxyborneol*	Drug Intermediate Drug Metabolite	Others
5-endo-Hydroxyborneol is a hydroxylation metabolite of a monoterpene compound. 5-endo-Hydroxyborneol can be used as a drug intermediate to synthesize optically pure compounds .

HY-12238G

IWR-1 endo-IWR 1; IWR-1-endo	Organoid Wnt	Inflammation/Immunology Cancer
IWR-1 (IWR-1-endo) (GMP) is the IWR-1 (HY-12238) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. IWR-1 (IWR-1-endo) is a tankyrase inhibitor targeting Wnt/β-catenin (IC₅₀ = 180 nM). IWR-1 compromises critical steps of the canonical Wnt signaling, namely translocation of β-catenin to the nucleus and subsequent TCF/LEF activation and expression of Wnt/β-catenin downstream targets. IWR-1 promotes β-catenin phosphorylation by promoting stability of Axin-scaffolded destruction complexes. IWR-1 can be studied in research for anti-tumor purposes, and diseases such as osteosarcoma, colorectal cancer and psoriasis .

Cat. No.	Product Name	Type

HY-149618

*Cy5-PEG3-endo-BCN*	Fluorescent Dye
Cy5-PEG3-endo-BCN is a derivative of the Cyanine 5 (Cy5) (HY-D0821) dye bearing 3 PEG units. Cy5-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN forms stable triazoles with azide-containing molecules under catalyst-free conditions .

HY-E70069GL

Endo S2, Streptococcus pyogenes (GMP Like)	Fluorescent Dye
Endo S2, Streptococcus pyogenes (GMP Like) is Endo S2, Streptococcus pyogenes (HY-E70069) produced by using GMP like guidelines. Endo-β-N-acetylglucosaminidase (Endo S2) is a key enzyme involved in the processing of free oligosaccharides in the cytosol. Endo-β-N-acetylglucosaminidase catalyzes hydrolysis of N-linked oligosaccharides .

HY-176559

LacNAc-VC-PAB-MMAE	Fluorescent Dye
LacNAc-VC-PAB-MMAE is a component of an Antibody-Drug Conjugate (ADC). LacNAc-VC-PAB-MMAE is assembled onto the N-glycosylation site of Trastuzumab (HY-P9907) by WT Endo-S2 .

HY-12238G

IWR-1

endo-IWR 1; IWR-1-endo

Fluorescent Dye

IWR-1 (IWR-1-endo) (GMP) is the IWR-1 (HY-12238) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. IWR-1 (IWR-1-endo) is a tankyrase inhibitor targeting Wnt/β-catenin (IC₅₀ = 180 nM). IWR-1 compromises critical steps of the canonical Wnt signaling, namely translocation of β-catenin to the nucleus and subsequent TCF/LEF activation and expression of Wnt/β-catenin downstream targets. IWR-1 promotes β-catenin phosphorylation by promoting stability of Axin-scaffolded destruction complexes. IWR-1 can be studied in research for anti-tumor purposes, and diseases such as osteosarcoma, colorectal cancer and psoriasis .

HY-155327

*Cy3-PEG2-endo-BCN*	Fluorescent Dye
Cy3-PEG2-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-149619

*Cy5-PEG7-endo-BCN*	Fluorescent Dye
Cy5-PEG7-endo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2121

*Cy3-PEG7-endo-BCN*	Fluorescent Dye
Cy3-PEG7-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2120

*Cy3-PEG3-endo-BCN*	Fluorescent Dye
Cy3-PEG3-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D3163

Endo-pH	Fluorescent Dye

Cat. No.	Product Name	Type

HY-W111141

BCN-OH endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne	Biochemical Assay Reagents
BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is an alcohol functionalized cyclooctyne derivative. BCN-OH can act as a raw material for synthesizing other probes (such as BCN-TPP). BCN-OH is used to construct targeted probes by coupling with carboxyl-containing compounds (such as TPP-COOH). BCN-OH can be used as control reagent for BCN-TPP .

HY-W879045

Endo-BCN-PEG5-amine endo-BCN-PEG5-NH2	Biochemical Assay Reagents
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-112624H

Dextran T2 (MW 2,000)

Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)

Biochemical Assay Reagents

Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM₂), and Isomaltotriose (IM₃). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .

HY-E70069GL

Endo S2, Streptococcus pyogenes (GMP Like)	Biochemical Assay Reagents
Endo S2, Streptococcus pyogenes (GMP Like) is Endo S2, Streptococcus pyogenes (HY-E70069) produced by using GMP like guidelines. Endo-β-N-acetylglucosaminidase (Endo S2) is a key enzyme involved in the processing of free oligosaccharides in the cytosol. Endo-β-N-acetylglucosaminidase catalyzes hydrolysis of N-linked oligosaccharides .

HY-166874

*DSPE-PEG2000-endo-BCN*	Biochemical Assay Reagents
DSPE-PEG2000-endo-BCN is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG2000-endo-BCN can be used in drug delivery research .

HY-12238G

IWR-1

endo-IWR 1; IWR-1-endo

Biochemical Assay Reagents

HY-W879025

Endo-BCN-PEG8-amine endo-BCN-PEG8-NH2	Biochemical Assay Reagents
Endo-BCN-PEG8-amine (Endo-BCN-PEG8-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-166871

*DSPE-PEG5000-endo-BCN*	Biochemical Assay Reagents
DSPE-PEG5000-endo-BCN is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG5000-endo-BCN can be used in drug delivery research .

HY-W879032

Endo-BCN-PEG4-Pomalidomide	Biochemical Assay Reagents
Endo-BCN-PEG4-Pomalidomide is a PEG derivative composed of BCN, PEG4 and Pomalidomide (HY-10984). The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-W879031

Endo-BCN-PEG4-Palmitic	Biochemical Assay Reagents
Endo-BCN-PEG4-Palmitic is a PEG derivative containing an endo-BCN cycloalkyne structure, a tetraethylene glycol (PEG4) linker, and a Palmitic acid (HY-N0830) fatty acid group. Endo-BCN-PEG4-Palmitic can be used for drug delivery, surface modification, and click chemistry reactions .

HY-W879044

Endo-BCN-PEG15-amine endo-BCN-PEG15-NH2	Biochemical Assay Reagents
Endo-BCN-PEG15-amine (Endo-BCN-PEG15-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-W793100

Endo-BCN-PEG2-Biotin	Biochemical Assay Reagents
Endo-BCN-PEG2-Biotin is a PEG linker containing a BCN group and a terminal carboxylic acid. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6840

Xylotetraose	Structural Classification Zea mays L. Polysaccharides Classification of Application Fields Gramineae Other Diseases Plants Disease Research Fields Saccharides Source Classification	Biochemical Assay Reagents
Xylotetraose is a xylo-oligosaccharide and a substrate of Taxy11. Xylotetraose serves as a substrate for the endo-xylanase Taxy11, and is hydrolyzed by it into xylobiose and xylotriose .

HY-N5132

(-)-Fenchone	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Other Diseases Umbelliferae Plants Vernonia Schreb. Disease Research Fields Source Classification	Cytochrome P450
(-)-Fenchone is a bicyclic monoterpene and serves as a substrate for human liver microsomal cytochrome P450 enzymes CYP2A6 and CYP2B6. (-)-Fenchone is not metabolized by human CYP1A1, CYP1A2, CYP1B1, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, or CYP3A4 enzymes. (-)-Fenchone undergoes hydroxylation to produce 6-exo-hydroxyfenchone, 6-endo-hydroxyfenchone, and 10-hydroxyfenchone. During the metabolism of (-)-Fenchone, CYP2A6 may play a more important role than CYP2B6 .

HY-125826

Heptasaccharide Glc4Xyl3	Polysaccharides Microorganisms Classification of Application Fields Metabolic Disease Disease Research Fields Saccharides Source Classification	Biochemical Assay Reagents
Heptasaccharide Glc4Xyl3, a covalent inhibitor of endo-xyloglucanases, is used for the identification and analysis of diverse xyloglucan-active enzymes in nature[1].

HY-N16572

*5-endo-Hydroxyborneol*	Structural Classification Other Monoterpenes Microorganisms Terpenoids Source Classification	Drug Intermediate Drug Metabolite
5-endo-Hydroxyborneol is a hydroxylation metabolite of a monoterpene compound. 5-endo-Hydroxyborneol can be used as a drug intermediate to synthesize optically pure compounds .

HY-121322

Neoagarobiose	Structural Classification Natural Products Microorganisms Source Classification	Others
Neoagarobiose has both a moisturizing effect on skin and a whitening effect on melanoma cells. RagaA11 is an endo-type beta-agarase hydrolysing not only agarose, but also neoagarotetraose, to yield neoagarobiose as the final main product .

HY-N5132R

(-)-Fenchone (Standard)	Structural Classification Other Monoterpenes Terpenoids Umbelliferae Plants Vernonia Schreb. Source Classification	Reference Standards Others
(-)-Fenchone (Standard) is the analytical standard of (-)-Fenchone. This product is intended for research and analytical applications. (-)-Fenchone, a bicyclic monoterpene, is widely distributed in plants and found in essential oils from Foeniculum vulgare. (-)-Fenchone is oxidized to 6-endo-hydroxyfenchone, 6-exo-hydroxyfenchone and 10-hydroxyfenchone derivatives by CYP2A6 and CYP2B6 in human liver microsomes with CYP2A6 playing a more important role than CYP2B6 .

Species:	Human (2) Rat (1) E.coli (1)
Tag:	His (7) Strep (1) Tag Free (2) Myc (2) Flag (1)
Source:	CHO (1) Sf9 insect cells (1) E. coli (7)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P79064

	Endo S2 Protein, S. pyogenes (His) Secreted endo-beta-N-acetylglucosaminidase (endoS); endoS; Spy49_1414c; endo-beta-N-acetylglucosaminidase S2	Others	E. coli
	Endo S2, secreted by Streptococcus pyogenes, deglycosylates the conserved N-linked glycan at Asn297 on IgG Fc to eliminate its effector functions and evade the immune system. EndoS2 specifically hydrolyzes diverse glycans on the Fc region of IgG antibodies using a mechanism that relies on its glycoside hydrolase domain and a coevolved carbohydrate-binding module. Endo S2 Protein, S. pyogenes (His) is the recombinant Endo S2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P78945

	ENDO VIII Protein, E. coli (His)	E.coli	E. coli
	ENDO VIII Protein, crucial in genetic recombination, DNA repair, and replication, performs essential activities like pairing and strand-transfer. It contributes to maintaining genomic integrity and forms intricate molecular networks by interacting with dda and gene 32 proteins. As a member of the RecA family, ENDO VIII Protein underscores its significance in broader cellular mechanisms related to DNA dynamics and genome stability. ENDO VIII Protein, E. coli (His) is the recombinant E. coli-derived ENDO VIII protein, expressed by E. coli , with N-6*His labeled tag. ENDO VIII Protein, E. coli (His), has molecular weight of ~44 kDa.

HY-P702174

	Beta-mannanase Protein, Lonsdalea quercina SAMN02982996_03194; Mannan endo-1; 4-beta-mannosidase	Others	E. coli
	Beta-mannanase is a member of the glycosyl hydrolase 26 family. Beta-mannanase Protein, Lonsdalea quercina is the recombinant Beta-mannanase protein, expressed by E. coli , with tag free.

HY-P702159

	pulB Protein, Pullulanibacillus naganoensis pulB; Alpha-dextrin endo-1; 6-alpha-glucosidase; Pullulan 6-glucanohydrolase	Others	E. coli
	PulB is a protein belonging to the glycosyl hydrolase 13 family. The glycosyl hydrolase 13 family contains enzymes involved in the breakdown of complex carbohydrates by catalyzing the hydrolysis of glycosidic bonds. pulB Protein, Pullulanibacillus naganoensis is the recombinant pulB protein, expressed by E. coli , with tag free.

HY-P702160

	pulB Protein, Pullulanibacillus naganoensis (FLAG, His) pulB; Alpha-dextrin endo-1; 6-alpha-glucosidase; Pullulan 6-glucanohydrolase	Others	E. coli
	PulB is a protein belonging to the glycosyl hydrolase 13 family. The glycosyl hydrolase 13 family contains enzymes involved in the breakdown of complex carbohydrates by catalyzing the hydrolysis of glycosidic bonds. pulB Protein, Pullulanibacillus naganoensis (FLAG, His) is the recombinant pulB protein, expressed by E. coli , with N-6*His, N-Flag labeled tag.

HY-P703527

	xynG1 Protein, Paenibacillus sp. (His, Strep) endo-1,4-beta-xylanase; Paenibacillus sp. 7541; Glycosidase; Hydrolase; 3.2.1.8	Others	E. coli
	xynG1 Protein, Paenibacillus sp. (His, Strep) is the recombinant xynG1 protein, expressed by E. coli, with Strep & His tag.

HY-P79276

	Heparanase/HPSE Protein, Human (CHO, His) Heparanase; endo-glucoronidase; Heparanase-1; Hpa1; HEP, HPA, HPA1, HPR1, HPSE1, HSE1; HPSE	Human	CHO
	Heparanase (HPSE) functions as an endoglycosidase, playing a crucial role in the cleavage of heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. It is implicated in various cellular processes, including facilitating cell migration associated with metastasis, wound healing, and inflammation. Heparanase also plays a role in cell adhesion to the ECM, independent of its enzymatic activity, and induces AKT1/PKB phosphorylation, thereby increasing cell mobility and invasion. Additionally, Heparanase is involved in the regulation of osteogenesis, promotes angiogenesis through up-regulation of SRC-mediated activation of VEGF, and is implicated in hair follicle inner root sheath differentiation and hair homeostasis. Heparanase/HPSE Protein, Human (CHO, His) is the recombinant human-derived Heparanase/HPSE protein, expressed by CHO , with N-6*His labeled tag.

HY-P72235

	HPSE Protein, Rat (His-Myc) Hpse; HepHeparanase; EC 3.2.1.166; endo-glucoronidase; Heparanase 8 kDa subunit; Heparanase 50 kDa subunit	Rat	E. coli
	HPSE proteins cleave HSPG into heparan sulfate side chains and decorin, involved in ECM degradation and remodeling. HPSE promotes cell migration associated with metastasis, wound healing, and inflammation and acts as a procoagulant. HPSE also induces AKT1/PKB phosphorylation, enhancing angiogenesis, hair follicle differentiation and homeostasis. HPSE Protein, Rat (His-Myc) is the recombinant rat-derived HPSE protein, expressed by E. coli , with N-10*His, C-Myc labeled tag.

HY-P72052

	KRT8 Protein, Human (sf9, His-Myc) CARD2; CK 8; CK-8; CK8; CYK8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; endoA; K2C8; K2C8_HUMAN; K8; Keratin 8; Keratin type II cytoskeletal 8 ; Keratin; type II cytoskeletal 8; Keratin-8; KO; Krt 2.8; KRT8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8	Human	Sf9 insect cells
	The KRT8 protein, in cooperation with KRT19, critically links the contractile apparatus of the striated rib muscle to dystrophin. This heterotetramer consists of two type I keratins and two type II keratins, forming a heterodimer with KRT18. KRT8 Protein, Human (sf9, His-Myc) is the recombinant human-derived KRT8 protein, expressed by Sf9 insect cells , with N-10*His, C-Myc labeled tag.

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Free Sample	Yes No
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Cat. No.	Product Name	Chemical Structure

HY-Z2483S

*Clopidogrel-MP endo* derivative-13C,d3**
Clopidogrel-MP endo derivative- ¹³C,d₃ is the deuterium and ¹³C labeled Clopidogrel-MP endo derivative .

Host:	Mouse (2) Rabbit (7)
Reactivity:	Human (9) Rat (6) Mouse (4)
Application:	IHC-P (6) ICC/IF (7) IF-Tissue (2) IP (2) IHC-F (2) WB (8) FC (2) ELISA (3)
Isotype:	IgG (7) IgG2b,IgG/Kappa (1) IgG1 (1)
Conjugation:	Non-conjugated (8)
Clonality:	Monoclonal (8) Recombinant (4)
Modification:	Unmodified (7)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81784

	Endo G Antibody (YA1529) endoG; endonucleaseG; Mitochondrial endonuclease G; NUCG_HUMAN	WB	Human, Mouse, Rat
	Endo G Antibody (YA1529) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Endo G.

HY-P82619

	MRC2 Antibody (YA2364) CD280 antigen; MRC2; endo180; KIAA0709; UPARAP	WB	Human
	MRC2 Antibody (YA2364) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MRC2.

HY-P80595

	CD146 Antibody (YA544) A32 antigen antibody; CD 146 antibody; CD146 antibody; CD146 antigen antibody; Cell surface glycoprotein MUC18 antibody; Cell surface glycoprotein P1H12 antibody; Gicerin antibody; Mcam antibody; Melanoma adhesion molecule antibody; Melanoma associated antigen A32 antibody; Melanoma associated antigen MUC18 antibody; Melanoma associated glycoprotein MUC18 antibody; Melanoma cell adhesion molecule antibody; Melanoma-associated antigen A32 antibody; Melanoma-associated antigen MUC18 antibody; MelCAM antibody; MUC 18 antibody; MUC18 antibody; MUC18_HUMAN antibody; S endo 1 antibody; S endo 1 endothelial associated antigen antibody; S-endo 1 endothelial-associated antigen antibody;	WB, IHC-F, IHC-P, ICC/IF	Human, Rat
	CD146 Antibody (YA544) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD146.

HY-P80595A

	CD146 Antibody (YA544)(PBS only) A32 antigen antibody; CD 146 antibody; CD146 antibody; CD146 antigen antibody; Cell surface glycoprotein MUC18 antibody; Cell surface glycoprotein P1H12 antibody; Gicerin antibody; Mcam antibody; Melanoma adhesion molecule antibody; Melanoma associated antigen A32 antibody; Melanoma associated antigen MUC18 antibody; Melanoma associated glycoprotein MUC18 antibody; Melanoma cell adhesion molecule antibody; Melanoma-associated antigen A32 antibody; Melanoma-associated antigen MUC18 antibody; MelCAM antibody; MUC 18 antibody; MUC18 antibody; MUC18_HUMAN antibody; S endo 1 antibody; S endo 1 endothelial associated antigen antibody; S-endo 1 endothelial-associated antigen antibody;	WB, IHC-F, IHC-P, ICC/IF	Human, Rat
	CD146 Antibody (YA544) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD146.

HY-P85790

	CD146 Antibody (YA5482) Cell surface glycoprotein MUC18; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD antigen CD146;	IHC-P, WB, ICC/IF, ELISA	Human
	CD146 Antibody (YA5482) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD146.

HY-P86410

	CD146 Antibody (YA6102) Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD antigen CD146)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	CD146 Antibody (YA6102) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD146.

HY-P85904

	Cytokeratin 8/18 Antibody (YA5596) CARD2; CK 8; CK-8; CK8; CYK8; CYKER; Cytokeratin endo A; CytokeRatin-8; DreK8; endoA; K2C8; K2C8_HUMAN; K8; KeRatin 8; KeRatin type II cytoskeletal 8; KeRatin, type II cytoskeletal 8; KeRatin-8; KO; Krt 2.8; KRT8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keRatin Kb8; CK 18; CK-18; CK18; CYK18; Cytokeratin 18; Cytokeratin endo B; CytokeRatin-18; K 18; K18; K1C18_HUMAN; KA18; KeRatin 18; KeRatin 18, type I; KeRatin D; keRatin, type I cytoskeletal 18; KeRatin-18; Krt18	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	Cytokeratin 8/18 Antibody (YA5596) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Cytokeratin 8/18.

HY-P86504

	Cytokeratin 8 Antibody (YA6196) CARD2; CK 8; CK-8; CK8; CYK8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; endoA; K2C8; K2C8_HUMAN; K8; Keratin 8; Keratin type II cytoskeletal 8; Keratin, type II cytoskeletal 8; Keratin-8; KO; Krt 2.8; KRT8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8	WB, IHC-P, ICC/IF, IP, FC, IF-Tissue	Human, Mouse, Rat
	Cytokeratin 8 Antibody (YA6196) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 8.

HY-P89399M

	Cytokeratin 8 Antibody (AF488) (YA6196) CARD2; CK 8; CK-8; CK8; CYK8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; endoA; K2C8; K2C8_HUMAN; K8; Keratin 8; Keratin type II cytoskeletal 8; Keratin, type II cytoskeletal 8; Keratin-8; KO; Krt 2.8; KRT8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8	ICC/IF, FC, IF-Tissue	Human
	Cytokeratin 8 Antibody (YA6196) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 8.

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Host
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-W035129

endo-BCN-NHS carbonate		BCN
endo-BCN-NHS carbonate is an elastin-like protein (ELP) modification reagent. endo-BCN-NHS carbonate can react with lysine residues in ELP to make ELP carry BCN groups, and then cross-link ELP through strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. endo-BCN-NHS carbonate promotes hydrogel formation. endo-BCN-NHS carbonate is mainly used in cell encapsulation related research .

HY-43581

endo-BCN-O-PNB		PROTAC Synthesis BCN
endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140069

endo-BCN-PEG4-NHS ester		PROTAC Synthesis BCN
endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W072752

endo-BCN-PEG2-NH2		BCN
endo-BCN-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG2-NH2 contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-141155

endo-BCN-PEG4-Val-Cit-PAB-MMAE 1 Publications Verification		BCN ADC Synthesis
endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable ADC linker conjugated with drug containing 4-unit PEG, which can be used for synthesizing antibody-drug conjugates (ADCs). endo-BCN-PEG4-Val-Cit-PAB-MMAE is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-133400

endo-BCN-PEG3-mal		BCN PROTAC Synthesis
endo-BCN-PEG3-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG3-mal is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W096079

*BCN-endo-PEG4-NHS*		ADC Synthesis BCN
BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-156311

*BCN-endo-PEG2-maleimide*		BCN ADC Synthesis
BCN-endo-PEG2-maleimide is an ADC Linker containing 4 PEG units. BCN-endo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

HY-157054

endo-BCN-L-Lysine		BCN PROTAC Synthesis
Endo-BCN-L-Lysine is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. Endo-BCN-L-Lysine contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W879045

Endo-BCN-PEG5-amine endo-BCN-PEG5-NH2		BCN
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-140070

endo-BCN-PEG8-NHS ester		PROTAC Synthesis BCN
endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-149618

*Cy5-PEG3-endo-BCN*		Labeling and Fluorescence Imaging BCN
Cy5-PEG3-endo-BCN is a derivative of the Cyanine 5 (Cy5) (HY-D0821) dye bearing 3 PEG units. Cy5-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN forms stable triazoles with azide-containing molecules under catalyst-free conditions .

HY-135971

endo-BCN-PEG4-acid		ADC Synthesis BCN
endo-BCN-PEG4-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . endo-BCN-PEG4-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140076

endo-BCN-PEG2-alcohol		PROTAC Synthesis BCN
endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG2-alcohol is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140073

endo-BCN-PEG4-PFP ester		BCN PROTAC Synthesis
endo-BCN-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-PFP ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140072

endo-BCN-PEG2-PFP ester		PROTAC Synthesis BCN
endo-BCN-PEG2-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG2-PFP ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140078

*bis-PEG2-endo-BCN*		ADC Synthesis BCN
bis-PEG2-endo-BCN is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . bis-PEG2-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-156317

*BCN-endo-PEG7-maleimide*		BCN
BCN-endo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-endo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-140068

endo-BCN-PEG3-NHS ester		BCN PROTAC Synthesis
endo-BCN-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG3-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-156310

*BCN-endo-PEG7-NH2*		BCN
BCN-endo-PEG7-NH2 is an ADC Linker containing 7 PEG units. BCN-endo-PEG7-NH2 contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-155327

*Cy3-PEG2-endo-BCN*		BCN Labeling and Fluorescence Imaging
Cy3-PEG2-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-130557

endo-BCN-PEG2-acid		PROTAC Synthesis BCN
endo-BCN-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. endo-BCN-PEG2-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140350

*5-endo-BCN-pentanoic acid*		PROTAC Synthesis BCN
5-endo-BCN-pentanoic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-endo-BCN-pentanoic acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-133008

endo-BCN-PEG3-acid		BCN
endo-BCN-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-140075

endo-BCN-PEG6-Boc		PROTAC Synthesis BCN
endo-BCN-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG6-Boc is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140080

*Gly-PEG3-endo-BCN*		PROTAC Synthesis BCN
Gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140081

*Boc-gly-PEG3-endo-BCN*		BCN ADC Synthesis PROTAC Synthesis
Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140074

endo-BCN-PEG4-Boc		BCN
endo-BCN-PEG4-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-133401

endo-BCN-PEG3-NH2		BCN PROTAC Synthesis
endo-BCN-PEG3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG3-NH2 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W879032

Endo-BCN-PEG4-Pomalidomide		BCN
Endo-BCN-PEG4-Pomalidomide is a PEG derivative composed of BCN, PEG4 and Pomalidomide (HY-10984). The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .

HY-W540023

endo-BCN-Fmoc-L-Lysine		BCN
Endo-BCN-Fmoc-L-Lysine is a linker containing the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-149619

*Cy5-PEG7-endo-BCN*		Labeling and Fluorescence Imaging BCN
Cy5-PEG7-endo-BCN is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG7-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-140065

endo-BCN-PEG8-acid		PROTAC Synthesis BCN
endo-BCN-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140066

endo-BCN-PEG12-acid		PROTAC Synthesis BCN
endo-BCN-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG12-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140079

*Bis-PEG23-endo-BCN*		BCN PROTAC Synthesis
Bis-PEG23-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bis-PEG23-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-139060

*Bis-PEG12-endo-BCN*		BCN PROTAC Synthesis
Bis-PEG12-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bis-PEG12-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-D2121

*Cy3-PEG7-endo-BCN*		Labeling and Fluorescence Imaging BCN
Cy3-PEG7-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-D2120

*Cy3-PEG3-endo-BCN*		Labeling and Fluorescence Imaging BCN
Cy3-PEG3-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 3 PEG units. Cy3-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.

HY-138386

endo-BCN-PEG12-NH2 hydrochloride		BCN PROTAC Synthesis
endo-BCN-PEG12-NH2 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG12-NH2 (hydrochloride) is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140077

endo-BCN-PEG3-NH-Boc		BCN
endo-BCN-PEG3-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-W590556

Endo-BCN-PEG4-Val-Cit-PAB-MMAF		BCN
Endo-BCN-PEG4-Val-Cit-PAB-MMAF is a cleavable ADC linker conjugated with drug containing 4-unit PEG, which can be used for synthesizing antibody-drug conjugates (ADCs). endo-BCN-PEG4-Val-Cit-PAB-MMAF is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-E70069GL

Endo S2, Streptococcus pyogenes (GMP Like)	Biochemical Assay Reagents	Infection
Endo S2, Streptococcus pyogenes (GMP Like) is Endo S2, Streptococcus pyogenes (HY-E70069) produced by using GMP like guidelines. Endo-β-N-acetylglucosaminidase (Endo S2) is a key enzyme involved in the processing of free oligosaccharides in the cytosol. Endo-β-N-acetylglucosaminidase catalyzes hydrolysis of N-linked oligosaccharides .

HY-12238G

IWR-1 endo-IWR 1; IWR-1-endo	Organoid Wnt	Inflammation/Immunology Cancer
IWR-1 (IWR-1-endo) (GMP) is the IWR-1 (HY-12238) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. IWR-1 (IWR-1-endo) is a tankyrase inhibitor targeting Wnt/β-catenin (IC₅₀ = 180 nM). IWR-1 compromises critical steps of the canonical Wnt signaling, namely translocation of β-catenin to the nucleus and subsequent TCF/LEF activation and expression of Wnt/β-catenin downstream targets. IWR-1 promotes β-catenin phosphorylation by promoting stability of Axin-scaffolded destruction complexes. IWR-1 can be studied in research for anti-tumor purposes, and diseases such as osteosarcoma, colorectal cancer and psoriasis .

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