exo-IWR-1
Based on 1 Customer Validation
exo-IWR-1, an inactive stereoisomer of Endo-IWR-1, is a negative control of IWR-1 (HY-12238). IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.75%
- CAS. Nr.: 1127442-87-8
- Formel: C25H19N3O3
- Molecular Weight:409.44
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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HY-101090
KYA1797KWnt/β-catenin Inhibitor -
HY-100830
NCB-0846TRAF2- and NCK-interacting Inhibitor -
HY-108439
NeurodazineNeurogenesis Inducer -
HY-16665
iCRT 14Wnt Inhibitor -
HY-122816
HLY78Wnt/β-catenin Activator -
HY-12238
IWR-1Wnt Signaling Inhibitor -
HY-12879
IWP-4Wnt/CK1δ/ε Inhibitor -
HY-19987
BML-284Wnt Signaling Activator -
HY-101130
PNU-74654β-catenin/TCF Interaction Inhibitor -
HY-13815
KY02111WNT Signaling/β-catenin Inhibitor -
HY-13912
IWP-2Wnt Production Inhibitor -
HY-10593
IQ 1Wnt/β-catenin/CBP Signaling Sustainer
Biologische Aktivität
Beschreibung
In Vitro
exo-IWR-1 (10 μM) does not influence the number of 293T cells infected with bunyaviruses[1].
Exo-IWR-1 had no effect on RVFV MP12-GFP infection when cells were either pretreated or treated 1 hpi[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1127442-87-8
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Appearance Solid
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Molecular Weight 409.44
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Formel C25H19N3O3
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Color Light yellow to green yellow
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SMILES
O=C(N1C(C=C2)=CC=C2C(NC3=CC=CC4=C3N=CC=C4)=O)[C@@]5([H])[C@](C1=O)([H])[C@H]6C[C@@H]5C=C6
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 2 mg/mL (4.88 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4424 mL | 12.2118 mL | 24.4236 mL | 61.0590 mL |
exo-IWR-1 Related Classifications
HY-108437 Related Classifications
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