1127442-87-8
1127442-87-8
Chemical Structure
exo-IWR-1
- CAS No.: 1127442-87-8
- Formula:C25H19N3O3
- Molecular Weight:409.44
IUPAC Name: 4-((3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)-N-(quinolin-8-yl)benzamide
InChIKey: ZGSXEXBYLJIOGF-BTYSMDAFSA-N
SMILES: O=C(N1C(C=C2)=CC=C2C(NC3=CC=CC4=C3N=CC=C4)=O)[C@@]5([H])[C@](C1=O)([H])[C@H]6C[C@@H]5C=C6
Biological Activity: exo-IWR-1, an inactive stereoisomer of Endo-IWR-1, is a negative control of IWR-1 (HY-12238). IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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exo-IWR-1 | 98.75% | exo-IWR-1, an inactive stereoisomer of Endo-IWR-1, is a negative control of IWR-1 (HY-12238). IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway. | ||||||||||||||||||||
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exo-IWR-1 (Standard) | ≥98% | exo-IWR-1 (Standard) is the analytical standard of exo-IWR-1 (HY-108437). This product is intended for research and analytical applications. exo-IWR-1, an inactive stereoisomer of Endo-IWR-1, is a negative control of IWR-1 (HY-12238). IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway. | ||||||||||||||||||||
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References
- [1]. Brooke Hamion, et al. Genome-wide RNA Interference Screen Identifies Novel Drug Targets for Rift Valley Fever Virus That Minimi the Potential for Drug Resistance.
- [2]. Brooke Harmon, et al. A Genome-Wide RNA Interference Screen Identifies a Role for Wnt/β-Catenin Signaling during Rift Valley Fever Virus Infection. J Virol. 2016 Jul 27;90(16):7084-7097. [Content Brief]
