1. Protein Tyrosine Kinase/RTK
  2. VEGFR
  3. VEGFR-2-IN-29

VEGFR-2-IN-29 

Cat. No.: HY-148040 Purity: 99.71%
COA Handling Instructions

VEGFR-2-IN-29 (Compound 5) is a VEGFR-2 inhibitor with an IC50 of 16.5 nM.

For research use only. We do not sell to patients.

VEGFR-2-IN-29 Chemical Structure

VEGFR-2-IN-29 Chemical Structure

CAS No. : 62802-77-1

Size Price Stock Quantity
5 mg USD 180 In-stock
Estimated Time of Arrival: December 31
10 mg USD 280 In-stock
Estimated Time of Arrival: December 31
25 mg USD 520 In-stock
Estimated Time of Arrival: December 31
50 mg USD 800 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

VEGFR-2-IN-29 (Compound 5) is a VEGFR-2 inhibitor with an IC50 of 16.5 nM[1].

IC50 & Target[1]

VEGFR-2

16.5 nM (IC50)

In Vitro

VEGFR-2-IN-29 (Compound 5) (72 h) inhibits HUVEC proliferation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: HUVEC
Concentration:
Incubation Time: 72 h
Result: Showed inhibition with IC50s of 15.8 nM and 210 nM against VEGF- and bFGF-induced HUVEC proliferation.
Molecular Weight

293.28

Formula

C16H11N3O3

CAS No.
SMILES

O=C(NC1=C2N=CC=CC2=CC=C1)C3=CC=CC([N+]([O-])=O)=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (68.19 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4097 mL 17.0486 mL 34.0971 mL
5 mM 0.6819 mL 3.4097 mL 6.8194 mL
10 mM 0.3410 mL 1.7049 mL 3.4097 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
VEGFR-2-IN-29
Cat. No.:
HY-148040
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