1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. endo-BCN-PEG4-Val-Cit-PAB-MMAE

endo-BCN-PEG4-Val-Cit-PAB-MMAE 

Cat. No.: HY-141155
Handling Instructions

endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

endo-BCN-PEG4-Val-Cit-PAB-MMAE Chemical Structure

endo-BCN-PEG4-Val-Cit-PAB-MMAE Chemical Structure

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Description

endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Molecular Weight

1546.93

Formula

C₈₀H₁₂₇N₁₁O₁₉

SMILES

CC[[email protected]@H]([[email protected]](N(C([[email protected]@H](NC([[email protected]@H](N(C(OCC1=CC=C(NC([[email protected]@H](NC([[email protected]@H](NC(CCOCCOCCOCCOCCNC(OCC2C3C2CCC#CCC3)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C1)=O)C)C(C)C)=O)C(C)C)=O)C)C(OC)CC(N4CCC[[email protected]]4[[email protected]](OC)[[email protected]](C(N[[email protected]@H]([[email protected]@H](O)C5=CC=CC=C5)C)=O)C)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

endo-BCN-PEG4-Val-Cit-PAB-MMAEADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product name:
endo-BCN-PEG4-Val-Cit-PAB-MMAE
Cat. No.:
HY-141155
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