Cy5-PEG3-endo-BCN
Based on 1 Customer Validation
Cy5-PEG3-endo-BCN is a derivative of the Cyanine 5 (Cy5) (HY-D0821) dye bearing 3 PEG units. Cy5-PEG3-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN forms stable triazoles with azide-containing molecules under catalyst-free conditions.
For research use only. We do not sell to patients.
- Purity: 98.40%
- CAS No.: 1881221-50-6
- Formula: C51H69ClN4O6
- Molecular Weight:869.57
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Cy5-PEG3-endo-BCN undergoes metal-free click chemistry with azide-functionalized AE105 (domain A) to generate the target probe (8b) with a purity of >95%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1881221-50-6
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Appearance Solid
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Molecular Weight 869.57
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Formula C51H69ClN4O6
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Color Purple to purplish red
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SMILES
CC1(C)C2=CC=CC=C2[N+](CCCCCC(NCCOCCOCCOCCNC(OC[C@H]3[C@]4([H])[C@@]3([H])CCC#CCC4)=O)=O)=C1/C=C/C=C/C=C5N(C6=CC=CC=C6C\5(C)C)C.[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 50 mg/mL (57.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1500 mL | 5.7500 mL | 11.4999 mL | 28.7498 mL |
| 5 mM | 0.2300 mL | 1.1500 mL | 2.3000 mL | 5.7500 mL | |
| 10 mM | 0.1150 mL | 0.5750 mL | 1.1500 mL | 2.8750 mL | |
| 15 mM | 0.0767 mL | 0.3833 mL | 0.7667 mL | 1.9167 mL | |
| 20 mM | 0.0575 mL | 0.2875 mL | 0.5750 mL | 1.4375 mL | |
| 25 mM | 0.0460 mL | 0.2300 mL | 0.4600 mL | 1.1500 mL | |
| 30 mM | 0.0383 mL | 0.1917 mL | 0.3833 mL | 0.9583 mL | |
| 40 mM | 0.0287 mL | 0.1437 mL | 0.2875 mL | 0.7187 mL | |
| 50 mM | 0.0230 mL | 0.1150 mL | 0.2300 mL | 0.5750 mL |
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