LacNAc-VC-PAB-MMAE
LacNAc-VC-PAB-MMAE is a component of an Antibody-Drug Conjugate (ADC). LacNAc-VC-PAB-MMAE is assembled onto the N-glycosylation site of Trastuzumab (HY-P9907) by WT Endo-S2.
For research use only. We do not sell to patients.
- Purity: 95.02%
- CAS No.: 2823367-88-8
- Formula: C74H116N12O23
- Molecular Weight:1541.78
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2823367-88-8
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Appearance Solid
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Molecular Weight 1541.78
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Formula C74H116N12O23
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Color White to off-white
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SMILES
O=C(CO/N=C/[C@H]1O[C@H]([C@@H]([C@H]([C@H]1O)O)O)O[C@H]2[C@@H]([C@H]3N=C(O[C@H]3O[C@@H]2CO)C)O)N[C@H](C(N[C@@H](CCCNC(N)=O)C(NC4=CC=C(COC(N(C)[C@H](C(N[C@H](C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N5CCC[C@H]5[C@@H]([C@H](C(N[C@@H]([C@@H](O)C6=CC=CC=C6)C)=O)C)OC)=O)=O)C(C)C)=O)C(C)C)=O)C=C4)=O)=O)C(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
DMSO : 50 mg/mL (32.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6486 mL | 3.2430 mL | 6.4860 mL | 16.2150 mL |
| 5 mM | 0.1297 mL | 0.6486 mL | 1.2972 mL | 3.2430 mL | |
| 10 mM | 0.0649 mL | 0.3243 mL | 0.6486 mL | 1.6215 mL | |
| 15 mM | 0.0432 mL | 0.2162 mL | 0.4324 mL | 1.0810 mL | |
| 20 mM | 0.0324 mL | 0.1622 mL | 0.3243 mL | 0.8108 mL | |
| 25 mM | 0.0259 mL | 0.1297 mL | 0.2594 mL | 0.6486 mL | |
| 30 mM | 0.0216 mL | 0.1081 mL | 0.2162 mL | 0.5405 mL |