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Non-ionic

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1890

Cremophor EL-40 Maximum Cited Publications 21 Publications Verification Polyoxyethylene(40) Castor Oil; PEG-40 Castor Oil	Environmental Pollutants Biochemical Assay Reagents	Others
Cremophor EL-40, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-40 is widely employed to improve dissolution and delivery of agents .

HY-128974

N-Dodecyl-β-D-maltoside 5 Publications Verification Lauryl Maltoside	DNA/RNA Synthesis	Others
N-Dodecyl-β-D-maltoside (Lauryl Maltoside) is a non-ionic detergent. N-Dodecyl-β-D-maltoside has strong adsorption on alumina, titanium dioxide and hematite. N-Dodecyl-β-D-maltoside can promote the reactivation of various proteins. N-Dodecyl-β-D-maltoside can effectively stabilize photoactive reaction center complexes (RCs) and inhibit the degradation of Rhodopseudomonas spheroides R-26 reaction center in solution. N-Dodecyl-β-D-maltoside can be used for purification and stabilization of RNA polymerase and for detection of protein-lipid interactions .

HY-116285

n-Octyl β-D-glucopyranoside 3 Publications Verification	Biochemical Assay Reagents	Others
n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins. n-Octyl-β-d-glucopyranoside can completely inhibit cavitation-induced cell lysis in vitro .

HY-125861

Methyl cellulose(Viscosity:100000mPa.s) 10+ Cited Publications MC(Viscosity:100000mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Methyl cellulose (MC) (Viscosity:100000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:100000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-141415

Tween 20 5 Publications Verification Polysorbate 20	Environmental Pollutants Biochemical Assay Reagents	Others
Tween 20 (Polysorbate 20) is a polyoxyethylene (POE)-type nonionic surfactant .

HY-B0594

Iohexol 5 Publications Verification	Autophagy Mitophagy	Cancer
Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging .

HY-B1068

Tyloxapol 5 Publications Verification	Biochemical Assay Reagents	Metabolic Disease
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surface active stabilizer. Tyloxapol is used to induce hyperlipidemia in animals .

HY-D1005A

Poloxamer 188 PEG-PPG-PEG, 8800 (Average Mn)	Environmental Pollutants Biochemical Assay Reagents	Inflammation/Immunology
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models. Poloxamer 188 can be used for drug delivery .

HY-A0104

HPMC (Viscosity:11250-21000mPa.s) 3 Publications Verification Hypromellose (Viscosity:11250-21000mPa.s); (Hydroxypropyl)methyl cellulose (Viscosity:11250-21000mPa.s); Celacol HPM 5000 (Viscosity:11250-21000mPa.s)	Environmental Pollutants Drug Intermediate Biochemical Assay Reagents	Cancer
HPMC (Viscosity:11250-21000mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices.

HY-A0104J

HPMC (Type II,Viscosity:5mPa.s) Hypromellose (Type II,Viscosity:5mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:5mPa.s); Celacol HPM 5000 (Type II,Viscosity:5mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
HPMC (Hypromellose) (Type II,Viscosity:5mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. HPMC (Type II,Viscosity:5mPa.s) is widely used in agent formulations due to its biocompatibility, uncharged nature, solubility in water and thermoplastic behavior .

HY-Y0873L

PEG800 Polyethylene glycol 800	Environmental Pollutants Biochemical Assay Reagents	Others
PEG800 (Polyethylene glycol 800) is a nonionic surfactant that is soluble in water and many polar solvents .

HY-138941

Octaethylene glycol monododecyl ether 1 Publications Verification C12E8	Influenza Virus	Infection
Octaethylene glycol monododecyl ether (C12E8) is an non-ionic detergent that can be used for membrane protein extraction. Octaethylene glycol monododecyl ether can solubilize the viral membrane of intact influenza virus .

HY-125861E

Methyl cellulose(Viscosity:4000mPa.s) 10+ Cited Publications MC(Viscosity:4000mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Methyl cellulose (MC) (Viscosity:4000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:4000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-401424

Cremophor EL-36 Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil	Environmental Pollutants Biochemical Assay Reagents	Others
Cremophor EL-36 is a non-ionic surfactant, mainly used as a solubilizing carrier for poorly soluble Paclitaxel (HY-B0015). For example, Cremophor EL-36 can enhance the intracellular influx of Etoposide (HY-13629) without affecting drug efflux, and can dose-dependently increase the accumulation of VP-16 in lung adenocarcinoma cells (such as PC-14 and A549), significantly enhancing its cytotoxic effect .

HY-125861B

Methyl cellulose(Viscosity:400mPa.s) 2 Publications Verification MC(Viscosity:400mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Methyl cellulose (MC) (Viscosity:400mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:400mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-B1620B

Polyvinylpyrrolidone K15 PVP K15; Polyvidone K15; Povidone K15	Environmental Pollutants Biochemical Assay Reagents	Others
Polyvinylpyrrolidone K15 is a linear non-ionic polymer devises vigorous bright crystalline layers and has adhesive, cohesive and dispersive properties .

HY-D1005H

Poloxamer 188 (F68) PEG-PPG-PEG, 8400(Average Mn)	Environmental Pollutants Biochemical Assay Reagents Fluorescent Dye	Others
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models .

HY-B1426

Iodixanol 3 Publications Verification	Biochemical Assay Reagents	Cancer
Iodixanol is an iodine-containing non-ionic radiocontrast agent .

HY-Y0850H

Polyvinyl alcohol (Mw 89000-98000, 99+% hydrolyzed) 3 Publications Verification PVA (Mw 89000-98000, 99+% hydrolyzed); Poly(Ethenol) (Mw 89000-98000, 99+% hydrolyzed)	Environmental Pollutants Biochemical Assay Reagents	Others
Polyvinyl alcohol (Mw 89000-98000, 99+% hydrolyzed) also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. It can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics .

HY-101530C

Polyoxyl 100 stearate PEG 100 stearate	Environmental Pollutants Biochemical Assay Reagents	Others
Polyoxyl 100 stearate (PEG-100 stearate) is a non-ionic surfactant formed by polyethylene glycol (PEG) and stearic acid, and it is commonly used in pharmaceutical preparations, nanocarriers, emulsification systems and cosmetic formulations .

HY-B1410

Ioversol MP-328	Biochemical Assay Reagents	Others Cancer
Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal .

HY-108294

Nonaethylene glycol monododecyl ether Nonaoxyethylene monododecyl ether	Biochemical Assay Reagents	Others
Nonaethylene glycol monododecyl ether (Nonaoxyethylene monododecyl ether) is a nonionic surfactant and polyethylene glycol (PEG) detergent that can be used to form initial coalesced O/W emulsion droplets, as well as for protein separation and purification .

HY-W129988

Sorbitan monododecanoate	Environmental Pollutants Biochemical Assay Reagents	Others
Sorbitan monododecanoate is a non-ionic surfactant, often used as an emulsifier in food, feed and topical preparations. Sorbitan monododecanoate can also be employed as a pharmaceutical excipient .

HY-125861A

Methyl cellulose(Viscosity:15mPa.s) 2 Publications Verification MC(Viscosity:15mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Methyl cellulose (MC) (Viscosity:15mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:15mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-Y0850I

Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) 3 Publications Verification PVA (Mw 9000-10000, 80% hydrolyzed); Poly(Ethenol) (Mw 9000-10000, 80% hydrolyzed)	Environmental Pollutants Biochemical Assay Reagents	Cancer
Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) can be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics, and cosmetics. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A) .

HY-B2106D

Polyoxyethylene (10) lauryl ether Decaethylene glycol monododecyl ether (C12E10); Polidocanol (10)	Biochemical Assay Reagents	Others Cancer
Polyoxyethylene (10) lauryl ether is a nonionic surfactant. Polyoxyethylene (10) lauryl ether exhibits unique properties in dissolving liposomes and exerts the minimal interference with endotoxin detection. Polyoxyethylene (10) lauryl ether forms hybrid liposomes with Dimyristoylphosphatidylcholine (DMPC) (HY-109541), which can inhibit the proliferation of human promyelocytic leukemia cells without the administration of any drugs .

HY-B1027

4-Nonylphenol polyethoxylate Nonoxynol; Nonoxinol	Environmental Pollutants Biochemical Assay Reagents	Others
4-Nonylphenol polyethoxylate (Nonoxynol) is a non-ionic surfactant. 4-Nonylphenol polyethoxylate forms degradation products including 4-nonylphenol and short ethoxyl chain polyethoxylates. 4-Nonylphenol polyethoxylate generates degradation products that exhibit estrogenic activity, persist in aquatic environments, and bioaccumulate in the food chain .

HY-W250168A

Polyoxyethylene(20) oleyl ether Polyethylene glycol oleyl ether, average Mn～1150; Polyethylene glycol monooleyl ether, n～20	Environmental Pollutants Biochemical Assay Reagents	Others
Polyoxyethylene(20) oleyl ether (Polyethylene glycol oleyl ether, with an average Mn of 1150) is a non-ionic surfactant. Polyoxyethylene(20) oleyl ether possesses emulsifying and detergent properties and can be used as a functional additive in drug delivery systems, helping to form stable nanoemulsions .

HY-125861C

Methyl cellulose(Viscosity:1500mPa.s) 2 Publications Verification MC(Viscosity:1500mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Methyl cellulose (MC) (Viscosity:1500mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:1500mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-Y0850K

Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed) 3 Publications Verification PVA (Mw 31000-50000, 98-99% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 98-99% hydrolyzed)	Environmental Pollutants Biochemical Assay Reagents	Cancer
Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed), also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. It can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A) .

HY-144007

Chol-PEG	Liposome	Others
Chol-PEG is a nonionic surfactant vesicles and can be used for a blood-persistent drug delivery system .

HY-B0684

Iopamidol 3 Publications Verification B-15000; SQ-13396	Biochemical Assay Reagents	Cancer
Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .

HY-101530

Polyoxyethylene stearate POES	Environmental Pollutants P-glycoprotein Bacterial	Cancer
Polyoxyethylene stearate (POES) is a non-ionic emulsifying agent.

HY-A0104E

HPMC (Type II,Viscosity:100mPa.s) Hypromellose (Type II,Viscosity:100mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:100mPa.s); Celacol HPM 5000 (Type II,Viscosity:100mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
HPMC (Hypromellose; (Hydroxypropyl)methyl cellulose; Celacol HPM 5000) (Type II,Viscosity:100mPa.s) is a non-ionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs in the hydrated matrix and the polymer relaxation process .

HY-W416291

Polyadenylic acid potassium Poly(A)	Biochemical Assay Reagents	Cancer
Polyadenylic acid potassium, also known as Poly(A), is enzymatically added to messenger RNA (mRNA) in eukaryotic cells to stabilize mRNAs. Poly(A) is used to evaluate binding on cationic liposomes doped with non-ionic nucleolipids. Poly(A) is used in small molecule mRNA targeted drug development to evaluate the binding of potential therapeutic agents such as the Isoquinoline group of alkaloids. Small molecules that could bind to this poly(A) tail could influence and possibly inhibit mRNA function and subsequent protein production in the cell leading to the development of new type of therapeutic agents.

HY-Y0850N

Polyvinyl alcohol (Mw 13000-23000, 98% hydrolyzed) 3 Publications Verification PVA (Mw 13000-23000, 98% hydrolyzed); Poly(Ethenol) (Mw 13000-23000, 98% hydrolyzed)	Environmental Pollutants Biochemical Assay Reagents	Cancer
Polyvinyl alcohol (PVA; Poly(Ethenol)) (Mw 13000-23000, 98% hydrolyzed) , also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. Polyvinyl alcohol (Mw 13000-23000, 98% hydrolyzed) can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics. Polyvinyl alcohol (Mw 13,000–23,000, 98% hydrolyzed) can be used in studies involving breast cancer as well as cisplatin (HY-17394)-induced sensorineural hearing loss .

HY-W129593

Sorbitan monooctadecanoate Sorbitan monostearate	Environmental Pollutants Biochemical Assay Reagents	Others
Sorbitan monooctadecanoate (Sorbitan monostearate) is a hydrophobic nonionic surfactant. Sorbitan monooctadecanoate can serve as a pharmaceutical excipient, such as an emulsifier, nonionic surfactant, solubilizer, wetting agent, and dispersing/suspending agent .

HY-A0104K

HPMC (Type II,Viscosity:3mPa.s) Hypromellose (Type II,Viscosity:3mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:3mPa.s); Celacol HPM 5000 (Type II,Viscosity:3mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
HPMC (Type II, Viscosity: 3 mPa.s) is a nonionic polymer prepared via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, which includes the diffusion of drugs in the hydrated matrix and the polymer relaxation process .

HY-A0104B

HPMC (Type I,Viscosity:100mPa.s) Hypromellose (Type I,Viscosity:100mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:100mPa.s); Celacol HPM 5000 (Type I,Viscosity:100mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
HPMC (Type I, Viscosity: 100 mPa·s) is a nonionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs within the hydrated matrix and the polymer relaxation process .

HY-B1362

Iopromide 2 Publications Verification	Biochemical Assay Reagents	Cardiovascular Disease
Iopromide is a non-ionic, monomeric, iodine-based contrast medium for intravascular administration.

HY-125861D

Methyl cellulose(Viscosity:40000mPa.s) 2 Publications Verification MC(Viscosity:40000mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Methyl cellulose (MC) (Viscosity:40000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:40000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-A0104I

HPMC (Type II,Viscosity:100000mPa.s) Hypromellose (Type II,Viscosity:100000mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:100000mPa.s); Celacol HPM 5000 (Type II,Viscosity:100000mPa.s)	Biochemical Assay Reagents	Others
HPMC (Hypromellose; (Hydroxypropyl)methyl cellulose; Celacol HPM 5000) (Type II,Viscosity:100000mPa.s) is a non-ionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs in the hydrated matrix and the polymer relaxation process .

HY-W129513

Sorbitan monopalmitate	Biochemical Assay Reagents	Others
Sorbitan monopalmitate is a food-grade, non-ionic emulsifier that exhibits oral activity. Sorbitan monopalmitate functions as a crystallization modifier, promoting the aggregation of spherical mango butter crystals, introducing lattice defects, and regulating the crystallization rate of mango butter. Sorbitan monopalmitate serves as a component of precursor vesicle gels, enabling the controlled and sustained release of drugs and facilitating the preparation of stable transdermal delivery formulations .

HY-B1941

4-tert-Octylphenol 2 Publications Verification	Endogenous Metabolite Apoptosis DNA/RNA Synthesis	Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology
4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .

HY-139415

Polyethylene glycol monoisotridecyl ether	Environmental Pollutants Biochemical Assay Reagents	Others
Polyethylene glycol monoisotridecyl ether is a nonionic surfactant widely used in cleaning, industrial, agricultural and other fields .

HY-123622

CYMAL-5, 98% (TLC)	Biochemical Assay Reagents	Others
CYMAL-5, 98% (TLC) is a cycloalkyl aliphatic saccharide. CYMAL-5, 98% (TLC) is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5, 98% (TLC) is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .

HY-W115727C

*Polyacrylamide,Nonionic,Mw 5-6 million* Acrylamide polymer,Nonionic,Mw 5-6 million	Biochemical Assay Reagents	Others
Polyacrylamide (Acrylamide polymer),Nonionic,Mw 5-6 million is a multifunctional, high-molecular-weight nonionic polyacrylamide copolymer. Polyacrylamide-based materials can maintain enzyme activity in enzyme immobilization, act as drug carriers for controlled release, function as smart materials responsive to temperature/pH stimuli, and be applied in in vitro toxin adsorption and soft tissue filling, through action mechanisms such as physical entrapment, covalent binding or chemical crosslinking. Polyacrylamide finds applications in biomedical engineering, environmental management and industrial applications .

HY-W392173

Lauryl glucoside (50% in water)	Biochemical Assay Reagents	Others
Lauryl glucoside (50% in water) is a non-ionic surfactant with high cleansing ability, high foaming ability and low cost .

HY-W099536

PEG 4 lauryl ether Tetraoxyethylene glycol monododecyl ether	Biochemical Assay Reagents	Others
PEG-4 lauryl ether is a non-ionic detergent that can be used as an excipient or for the isolation of functional membrane complexes .

HY-W250316

Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate Sucrose Stearate, Type II, USP	Biochemical Assay Reagents	Others
Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate (Sucrose Stearate, Type II, USP) is a non-ionic surfactant. Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate enhances the skin permeability of formulations .

Cat. No.	Product Name	Type

HY-Y1890

Cremophor EL-40 Maximum Cited Publications 21 Publications Verification Polyoxyethylene(40) Castor Oil; PEG-40 Castor Oil	Biochemical Assay Reagents
Cremophor EL-40, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-40 is widely employed to improve dissolution and delivery of agents .

HY-116285

n-Octyl β-D-glucopyranoside 3 Publications Verification	Biochemical Assay Reagents
n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins. n-Octyl-β-d-glucopyranoside can completely inhibit cavitation-induced cell lysis in vitro .

HY-D1005

Poloxamer 407 (F127) 5+ Cited Publications PEG-PPG-PEG, 12600 (Average Mn)	Biochemical Assay Reagents
Poloxamer 407 (F127) is a nonionic surfactant that is 100% active and relatively non-toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8 AM and Quest Rhod-4 AM, etc. to improve their water solubility. Poloxamer 407 is also a lipoprotein lipase inhibitor .

HY-125861

Methyl cellulose(Viscosity:100000mPa.s) 10+ Cited Publications MC(Viscosity:100000mPa.s)	Biochemical Assay Reagents
Methyl cellulose (MC) (Viscosity:100000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:100000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-141415

Tween 20 5 Publications Verification Polysorbate 20	Biochemical Assay Reagents
Tween 20 (Polysorbate 20) is a polyoxyethylene (POE)-type nonionic surfactant .

HY-D1005A

Poloxamer 188 PEG-PPG-PEG, 8800 (Average Mn)	Biochemical Assay Reagents
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models. Poloxamer 188 can be used for drug delivery .

HY-A0104

HPMC (Viscosity:11250-21000mPa.s) 3 Publications Verification Hypromellose (Viscosity:11250-21000mPa.s); (Hydroxypropyl)methyl cellulose (Viscosity:11250-21000mPa.s); Celacol HPM 5000 (Viscosity:11250-21000mPa.s)	Biochemical Assay Reagents
HPMC (Viscosity:11250-21000mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices.

HY-Y0873L

PEG800 Polyethylene glycol 800	Biochemical Assay Reagents
PEG800 (Polyethylene glycol 800) is a nonionic surfactant that is soluble in water and many polar solvents .

HY-Y1883

Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant

Maximum Cited Publications

24 Publications Verification

Biochemical Assay Reagents

Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .

HY-125861E

Methyl cellulose(Viscosity:4000mPa.s) 10+ Cited Publications MC(Viscosity:4000mPa.s)	Biochemical Assay Reagents
Methyl cellulose (MC) (Viscosity:4000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:4000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-401424

Cremophor EL-36

Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil

Biochemical Assay Reagents

Cremophor EL-36 is a non-ionic surfactant, mainly used as a solubilizing carrier for poorly soluble Paclitaxel (HY-B0015). For example, Cremophor EL-36 can enhance the intracellular influx of Etoposide (HY-13629) without affecting drug efflux, and can dose-dependently increase the accumulation of VP-16 in lung adenocarcinoma cells (such as PC-14 and A549), significantly enhancing its cytotoxic effect .

HY-125861B

Methyl cellulose(Viscosity:400mPa.s) 2 Publications Verification MC(Viscosity:400mPa.s)	Biochemical Assay Reagents
Methyl cellulose (MC) (Viscosity:400mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:400mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-B1620B

Polyvinylpyrrolidone K15 PVP K15; Polyvidone K15; Povidone K15	Biochemical Assay Reagents
Polyvinylpyrrolidone K15 is a linear non-ionic polymer devises vigorous bright crystalline layers and has adhesive, cohesive and dispersive properties .

HY-D1005H

Poloxamer 188 (F68) PEG-PPG-PEG, 8400(Average Mn)	Biochemical Assay Reagents
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models .

HY-Y0850H

Polyvinyl alcohol (Mw 89000-98000, 99+% hydrolyzed) 3 Publications Verification PVA (Mw 89000-98000, 99+% hydrolyzed); Poly(Ethenol) (Mw 89000-98000, 99+% hydrolyzed)	Biochemical Assay Reagents
Polyvinyl alcohol (Mw 89000-98000, 99+% hydrolyzed) also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. It can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics .

HY-W250168

Polyoxyethylene(10) oleyl ether

Polyethylene glycol oleyl ether, average Mn～709; Polyethylene glycol monooleyl ether, n～10

Biochemical Assay Reagents

Polyoxyethylene(10) oleyl ether, also known as POE(10) monooleate, is a nonionic surfactant consisting of a polyethylene glycol chain with 10 ethylene oxide units and an oleic acid residue. It has excellent emulsifying, wetting and dispersing properties, making it suitable for a variety of applications including personal care products and pharmaceutical formulations. POE(10) monooleate is commonly used as a solubilizer to improve the solubility and bioavailability of poorly soluble drugs. Furthermore, it is biodegradable and has low toxicity, making it an environmentally friendly ingredient suitable for various industrial applications.

HY-125861A

Methyl cellulose(Viscosity:15mPa.s) 2 Publications Verification MC(Viscosity:15mPa.s)	Biochemical Assay Reagents
Methyl cellulose (MC) (Viscosity:15mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:15mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-Y0850I

Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed)

3 Publications Verification

PVA (Mw 9000-10000, 80% hydrolyzed); Poly(Ethenol) (Mw 9000-10000, 80% hydrolyzed)

Biochemical Assay Reagents

Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) can be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics, and cosmetics. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A) .

HY-B2106D

Polyoxyethylene (10) lauryl ether

Decaethylene glycol monododecyl ether (C12E10); Polidocanol (10)

Biochemical Assay Reagents

Polyoxyethylene (10) lauryl ether is a nonionic surfactant. Polyoxyethylene (10) lauryl ether exhibits unique properties in dissolving liposomes and exerts the minimal interference with endotoxin detection. Polyoxyethylene (10) lauryl ether forms hybrid liposomes with Dimyristoylphosphatidylcholine (DMPC) (HY-109541), which can inhibit the proliferation of human promyelocytic leukemia cells without the administration of any drugs .

HY-W250168A

Polyoxyethylene(20) oleyl ether Polyethylene glycol oleyl ether, average Mn～1150; Polyethylene glycol monooleyl ether, n～20	Biochemical Assay Reagents
Polyoxyethylene(20) oleyl ether (Polyethylene glycol oleyl ether, with an average Mn of 1150) is a non-ionic surfactant. Polyoxyethylene(20) oleyl ether possesses emulsifying and detergent properties and can be used as a functional additive in drug delivery systems, helping to form stable nanoemulsions .

HY-125861C

Methyl cellulose(Viscosity:1500mPa.s) 2 Publications Verification MC(Viscosity:1500mPa.s)	Biochemical Assay Reagents
Methyl cellulose (MC) (Viscosity:1500mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:1500mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-Y0850K

Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed)

3 Publications Verification

PVA (Mw 31000-50000, 98-99% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 98-99% hydrolyzed)

Biochemical Assay Reagents

Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed), also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. It can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A) .

HY-144007

Chol-PEG	Biochemical Assay Reagents
Chol-PEG is a nonionic surfactant vesicles and can be used for a blood-persistent drug delivery system .

HY-15435A

CHAPS hydrate

4 Publications Verification

Biochemical Assay Reagents

CHAPS hydrate is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS hydrate exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS hydrate stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm‑Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS hydrate is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS hydrate cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS hydrate is commonly used in research on the separation and purification of membrane proteins .

HY-A0104E

HPMC (Type II,Viscosity:100mPa.s) Hypromellose (Type II,Viscosity:100mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:100mPa.s); Celacol HPM 5000 (Type II,Viscosity:100mPa.s)	Biochemical Assay Reagents
HPMC (Hypromellose; (Hydroxypropyl)methyl cellulose; Celacol HPM 5000) (Type II,Viscosity:100mPa.s) is a non-ionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs in the hydrated matrix and the polymer relaxation process .

HY-Y0850N

Polyvinyl alcohol (Mw 13000-23000, 98% hydrolyzed)

3 Publications Verification

PVA (Mw 13000-23000, 98% hydrolyzed); Poly(Ethenol) (Mw 13000-23000, 98% hydrolyzed)

Biochemical Assay Reagents

Polyvinyl alcohol (PVA; Poly(Ethenol)) (Mw 13000-23000, 98% hydrolyzed) , also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. Polyvinyl alcohol (Mw 13000-23000, 98% hydrolyzed) can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics. Polyvinyl alcohol (Mw 13,000–23,000, 98% hydrolyzed) can be used in studies involving breast cancer as well as cisplatin (HY-17394)-induced sensorineural hearing loss .

HY-A0104B

HPMC (Type I,Viscosity:100mPa.s) Hypromellose (Type I,Viscosity:100mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:100mPa.s); Celacol HPM 5000 (Type I,Viscosity:100mPa.s)	Biochemical Assay Reagents
HPMC (Type I, Viscosity: 100 mPa·s) is a nonionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs within the hydrated matrix and the polymer relaxation process .

HY-B1937

Sodium dodecylbenzenesulfonate

Bio-Soft S 101 sodium

Biochemical Assay Reagents

Sodium dodecylbenzenesulfonate (Bio-Soft S 101 sodium) is a nonionic surfactant commonly used in a variety of applications for cleaning and treating industrial equipment. It has good cleaning power and environmental compatibility, and can effectively remove oil, dirt and other forms of contamination. In addition, in textile, paper, leather and other industries, the compound can also be used for fixing and stabilizing dyes and colors. Although the compound has no direct application in the medical field, it plays an important role in industry and laboratory research.

HY-W250166

Polyoxyethylene tridecyl ether

Biochemical Assay Reagents

Poly(ethylene glycol) (12) tridecyl ether is a nonionic surfactant belonging to the family of ethoxylated fatty alcohols. It is commonly used as an emulsifier, solubilizer, and wetting agent in a variety of industrial and personal care products. Poly(ethylene glycol)(12) tridecyl ether has various properties that make it suitable for these applications, including its low toxicity, high solubility in water and organic solvents, and ability to stabilize emulsions. In addition, it can be used as a raw material for the production of other surfactants and specialty chemicals.

HY-W250195

Hexaethylene glycol monotetradecyl ether

Biochemical Assay Reagents

Hexaethylene glycol monotetradecyl ether is a kind of nonionic surfactant with hydrophilic head and lipophilic tail. It belongs to the class of polyethylene glycol (PEG) ethers and is widely used in different industrial and research applications. Due to its unique properties, Hexaethylene glycol monotetradecyl ether is commonly used in lotions, detergents and solubilizers. It is particularly useful in the study of membrane proteins and can be used to stabilize and solubilize proteins for use in structural analysis techniques. Due to its moisturizing and emulsifying properties, Hexaethylene glycol monotetradecyl ether is also used in personal care and cosmetics.

HY-A0104I

HPMC (Type II,Viscosity:100000mPa.s) Hypromellose (Type II,Viscosity:100000mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:100000mPa.s); Celacol HPM 5000 (Type II,Viscosity:100000mPa.s)	Biochemical Assay Reagents
HPMC (Hypromellose; (Hydroxypropyl)methyl cellulose; Celacol HPM 5000) (Type II,Viscosity:100000mPa.s) is a non-ionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs in the hydrated matrix and the polymer relaxation process .

HY-139415

Polyethylene glycol monoisotridecyl ether	Biochemical Assay Reagents
Polyethylene glycol monoisotridecyl ether is a nonionic surfactant widely used in cleaning, industrial, agricultural and other fields .

HY-123622

CYMAL-5, 98% (TLC)

Biochemical Assay Reagents

CYMAL-5, 98% (TLC) is a cycloalkyl aliphatic saccharide. CYMAL-5, 98% (TLC) is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5, 98% (TLC) is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .

HY-W115727C

Polyacrylamide,Nonionic,Mw 5-6 million

Acrylamide polymer,Nonionic,Mw 5-6 million

Biochemical Assay Reagents

Polyacrylamide (Acrylamide polymer),Nonionic,Mw 5-6 million is a multifunctional, high-molecular-weight nonionic polyacrylamide copolymer. Polyacrylamide-based materials can maintain enzyme activity in enzyme immobilization, act as drug carriers for controlled release, function as smart materials responsive to temperature/pH stimuli, and be applied in in vitro toxin adsorption and soft tissue filling, through action mechanisms such as physical entrapment, covalent binding or chemical crosslinking. Polyacrylamide finds applications in biomedical engineering, environmental management and industrial applications .

HY-W392173

Lauryl glucoside (50% in water)	Biochemical Assay Reagents
Lauryl glucoside (50% in water) is a non-ionic surfactant with high cleansing ability, high foaming ability and low cost .

HY-W250316

Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate Sucrose Stearate, Type II, USP	Biochemical Assay Reagents
Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate (Sucrose Stearate, Type II, USP) is a non-ionic surfactant. Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate enhances the skin permeability of formulations .

HY-125861H

Methyl cellulose(Viscosity:25mPa.s) MC(Viscosity:25mPa.s)	Biochemical Assay Reagents
Methyl cellulose (MC) (Viscosity:25mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:25mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-D1005I

Poloxamer L61

Biochemical Assay Reagents

Poloxamer L61 is a non-ionic triblock copolymer surfactant. Poloxamer L61 effectively achieves intracellular molecular delivery to cancer cells during photoacoustic molecular delivery, and maintains cell viability by promoting cell membrane resealing, thus avoiding irreversible damage caused by laser-induced membrane permeabilization. Poloxamer L61 is a key component of SP1017, a compound related to gene therapy, which regulates the interaction between DNA and extracellular matrix as well as cellular uptake, and significantly enhances the distribution and bioavailability of plasmid DNA in skeletal muscle. Poloxamer L61 can be used in studies on local or systemic therapeutic protein production .

HY-W274569

Hexyl-β-D-glucopyranoside, 98%	Biochemical Assay Reagents
Hexyl-β-D-glucopyranoside, 98% is typically used as a mild nonionic detergent.

HY-Y1890C

Cremophor EL-20	Biochemical Assay Reagents
Cremophor EL-20 is a type of Cremophor EL. Cremophor EL is a nonionic surfactant .

HY-W040217

MEGA-10 N-Oxodecyl meglumine; Decanoyl N-methylglucamide	Biochemical Assay Reagents
MEGA-10 (N-Oxodecyl meglumine) is a nonionic sugar-based surfactant. MEGA-10 sequesters n-alkylbenzenes into its hydrophobic core via micelle formation as a solubilizer .

HY-W127624

Polyoxyethylene monocetyl ether (n=approx. 23)	Biochemical Assay Reagents
Polyoxyethylene monocetyl ether (n=approx. 23) is a nonionic surfactant and can be used to manufacture hand sanitizer, laundry detergent, body wash, laundry powder, dish soap, metal cleaning agents and other products .

HY-W250170

Decyl glucoside (60% in water) Octyldecyl glucoside	Biochemical Assay Reagents
Decyl glucoside is a mild nonionic surfactant. Decyl glucoside can be derived from renewable raw materials such as glucose and fatty alcohols from coconut oil or palm kernel oil. Decyl glucoside is known for its excellent foaming and cleaning properties.

HY-D1005A5

Poloxamer 123 (L43) PEG-PPG-PEG, 1850 (Average)	Biochemical Assay Reagents
Poloxamer 123 (L43) (PEG-PPG-PEG, average molecular weight 1850) is a nonionic triblock copolymer of polyoxyethylene-polyoxypropylene-polyoxyethylene with an average molecular weight of 1850. Poloxamer 123 L43 can be used as a surfactant, emulsifier, and solubilizer in cosmetics .

HY-Y1890B

Cremophor EL-10

Biochemical Assay Reagents

Cremophor EL-10 is a nonionic polyoxyethylene castor oil surfactant with multiple functions including organic solubilizer, mixed zinc anode corrosion inhibitor and dendrite growth inhibitor. By forming a physical barrier to block electrolyte contact and constructing oriented hydration channels to reduce the desolvation energy barrier of Zn ²⁺, Cremophor EL-10 achieves a corrosion inhibition efficiency of over 99%. Cremophor EL-10 exerts no significant effects on the mitochondrial activity and cell viability of epithelial cells, making it suitable for in vitro drug delivery and biopharmaceutical research at concentrations ≤10% v/v. However, Cremophor EL-10 may induce sustained non-endothelium-dependent contraction in rat aortic rings and exert concentration-dependent inhibitory effects on acetylcholine-induced endothelium-dependent relaxation responses .

HY-W250172

Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O)

Biochemical Assay Reagents

Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is a nonionic surfactant commonly used in a variety of industrial and research applications. Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in emulsions, detergents and solubilizers. Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. It is also used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Additionally, Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is used in the production of microemulsions, salves and lotions due to its emulsifying and solubilizing properties. However, it can be toxic if ingested or inhaled, so proper handling and safety precautions are required.

HY-Y0850U5

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

Polyvinyl alcohol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

Biochemical Assay Reagents

PVA (Polyvinyl alcohol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) is a nonionic ethanol homopolymer with hydrophilicity, water solubility and biodegradability. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) exhibits biocompatibility, non-toxicity and non-carcinogenicity, as well as antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can serve as a solubilizer, stabilizer, mucoadhesive agent and sustained-release agent, and has a synergistic solubilizing effect on voriconazole/sulfobutyl ether β-cyclodextrin complexes. By stabilizing such complexes, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) forms freeze-thaw hydrogels with high mucoadhesion, sustained drug release and ex vivo corneal permeability. When compounded with hyaluronic acid hydrogels, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) supports chondrocyte growth in vitro, and also forms complexes with Cu ²⁺, Co ²⁺, Ni ²⁺ and Zn ²⁺ ions. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can be used in studies related to fungal keratitis, bacterial infections and fungal infections .

HY-W142692

Dodecyl β-D-glucopyranoside

Biochemical Assay Reagents

Dodecyl β-D-glucopyranoside is a non-ionic detergent and surfactant commonly used to solubilize and purify membrane proteins in biochemical research. Dodecyl β-D-glucopyranoside also interacts with bovine serum albumin (BSA) to quench its intrinsic fluorescence. The critical micelle concentration (CMC) of Dodecyl β-D-glucopyranoside (DG) and DG/BSA complex is 2.0 mM and 2.34 mM, respectively. Micelles can be formed in aqueous solutions above this concentration .

HY-Y1890H

Cremophor EL-90	Biochemical Assay Reagents
Cremophor EL-90, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-90 has good emulsifying properties .

HY-Y1890D

Cremophor EL-60	Biochemical Assay Reagents
Cremophor EL-60, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-60 has good emulsifying properties .

Cat. No.	Product Name	Target	Research Area

HY-W250166

Polyoxyethylene tridecyl ether	Environmental Pollutants Biochemical Assay Reagents	Others
Poly(ethylene glycol) (12) tridecyl ether is a nonionic surfactant belonging to the family of ethoxylated fatty alcohols. It is commonly used as an emulsifier, solubilizer, and wetting agent in a variety of industrial and personal care products. Poly(ethylene glycol)(12) tridecyl ether has various properties that make it suitable for these applications, including its low toxicity, high solubility in water and organic solvents, and ability to stabilize emulsions. In addition, it can be used as a raw material for the production of other surfactants and specialty chemicals.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1941

4-tert-Octylphenol 2 Publications Verification	Monophenols Neurological Disease Classification of Application Fields Phenols Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Endogenous Metabolite Apoptosis DNA/RNA Synthesis
4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .

HY-B1941R

4-tert-Octylphenol (Standard)	Monophenols Phenols Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Apoptosis DNA/RNA Synthesis
4-tert-Octylphenol (Standard) is the analytical standard of 4-tert-Octylphenol. This product is intended for research and analytical applications. 4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .

HY-N18642

Soapnut extract	Structural Classification Extract	Bacterial
Soapnut extract is a natural nonionic surfactant that can be used as a skin conditioning agent. It possesses strong detergency, antibacterial, non-polluting, and skin-softening properties. Soapnut extract also exhibits anti-inflammatory, antioxidant, free radical scavenging, and anticoagulant effects.

Cat. No.	Product Name	Chemical Structure

HY-128974S

N-Dodecyl-β-D-maltoside-d25

N-Dodecyl-β-D-maltoside-d₂₅ (Lauryl Maltoside-d₂₅) is deuterium labeled N-Dodecyl-β-D-maltoside (HY-128974). N-Dodecyl-β-D-maltoside is a non-ionic detergent. N-Dodecyl-β-D-maltoside has strong adsorption on alumina, titanium dioxide and hematite. N-Dodecyl-β-D-maltoside can promote the reactivation of various proteins. N-Dodecyl-β-D-maltoside can effectively stabilize photoactive reaction center complexes (RCs) and inhibit the degradation of Rhodopseudomonas spheroides R-26 reaction center in solution. N-Dodecyl-β-D-maltoside can be used for purification and stabilization of RNA polymerase and for detection of protein-lipid interactions .

HY-116285S1

1-O-n-Octyl-β-D-glucopyranoside-d17
1-O-n-Octyl-β-D-glucopyranoside-d₁₇ is the deuterium labeled n-Octyl β-D-glucopyranoside . n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins .

HY-B1362S

Iopromide-d3
Iopromide-d₃ is the deuterium labeled Iopromide. Iopromide is a non-ionic, monomeric, iodine-based contrast medium for intravascular administration.

HY-W777582

4-tert-Octylphenol monoethoxylate-13C6

4-tert-Octylphenol monoethoxylate- ¹³C₆ is the ¹³C labeled isotope of 4-tert-Octylphenol monoethoxylate (HY-W777582) . 4-tert-Octylphenol monoethoxylate is an alkylphenolethoxylate (APE) and a degradation product of non-ionic surfactants (such as 4-tert-octylphenol polyethoxylate). 4-tert-Octylphenol monoethoxylate also possesses non-steroidal estrogenic activity. Additionally, 4-tert-Octylphenol monoethoxylate has been found in wastewater effluent .

HY-B0684S

Iopamidol-d8
Iopamidol-d₈ (B-15000-d₈) is the deuterium labeled Iopamidol. Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .

HY-B0684S1

Iopamidol-d3
Iopamidol-d₃ (B-15000-d₃; SQ-13396-d₃) is the deuterium labeled Iopamidol (HY-B0684). Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast .

Cat. No.	Product Name		Classification

HY-Y1890

Cremophor EL-40 Maximum Cited Publications 21 Publications Verification Polyoxyethylene(40) Castor Oil; PEG-40 Castor Oil		Emulsifiers Solubilizing Agents Surfactants
Cremophor EL-40, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-40 is widely employed to improve dissolution and delivery of agents .

HY-D1005

Poloxamer 407 (F127) 5+ Cited Publications PEG-PPG-PEG, 12600 (Average Mn)		Emulsifiers Solubilizing Agents
Poloxamer 407 (F127) is a nonionic surfactant that is 100% active and relatively non-toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8 AM and Quest Rhod-4 AM, etc. to improve their water solubility. Poloxamer 407 is also a lipoprotein lipase inhibitor .

HY-125861

Methyl cellulose(Viscosity:100000mPa.s) 10+ Cited Publications MC(Viscosity:100000mPa.s)		Emulsifiers Disintegrants Suspending Agents
Methyl cellulose (MC) (Viscosity:100000mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:100000mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction .

HY-141415

Tween 20 5 Publications Verification Polysorbate 20		Emulsifiers Solubilizing Agents Surfactants
Tween 20 (Polysorbate 20) is a polyoxyethylene (POE)-type nonionic surfactant .

HY-D1005A

Poloxamer 188 PEG-PPG-PEG, 8800 (Average Mn)		Emulsifiers Solubilizing Agents
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models. Poloxamer 188 can be used for drug delivery .

HY-A0104

HPMC (Viscosity:11250-21000mPa.s) 3 Publications Verification Hypromellose (Viscosity:11250-21000mPa.s); (Hydroxypropyl)methyl cellulose (Viscosity:11250-21000mPa.s); Celacol HPM 5000 (Viscosity:11250-21000mPa.s)		Thickeners Suspending Agents
HPMC (Viscosity:11250-21000mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices.

HY-D1005H

Poloxamer 188 (F68) PEG-PPG-PEG, 8400(Average Mn)		Polymers
Poloxamer 188 is a nonionic linear copolymer with surfactant properties. Poloxamer 188 exhibits anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models .

HY-Y0850H

Polyvinyl alcohol (Mw 89000-98000, 99+% hydrolyzed) 3 Publications Verification PVA (Mw 89000-98000, 99+% hydrolyzed); Poly(Ethenol) (Mw 89000-98000, 99+% hydrolyzed)		Polymers
Polyvinyl alcohol (Mw 89000-98000, 99+% hydrolyzed) also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. It can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics .

HY-101530C

Polyoxyl 100 stearate PEG 100 stearate		Emulsifiers Bases Solubilizing Agents
Polyoxyl 100 stearate (PEG-100 stearate) is a non-ionic surfactant formed by polyethylene glycol (PEG) and stearic acid, and it is commonly used in pharmaceutical preparations, nanocarriers, emulsification systems and cosmetic formulations .

HY-108294

Nonaethylene glycol monododecyl ether Nonaoxyethylene monododecyl ether		Solvents
Nonaethylene glycol monododecyl ether (Nonaoxyethylene monododecyl ether) is a nonionic surfactant and polyethylene glycol (PEG) detergent that can be used to form initial coalesced O/W emulsion droplets, as well as for protein separation and purification .

HY-W129988

Sorbitan monododecanoate		Emulsifiers Surfactants
Sorbitan monododecanoate is a non-ionic surfactant, often used as an emulsifier in food, feed and topical preparations. Sorbitan monododecanoate can also be employed as a pharmaceutical excipient .

HY-Y0850K

Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed) 3 Publications Verification PVA (Mw 31000-50000, 98-99% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 98-99% hydrolyzed)		Polymers
Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed), also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. It can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A) .

HY-144007

Chol-PEG		Cholesterol
Chol-PEG is a nonionic surfactant vesicles and can be used for a blood-persistent drug delivery system .

HY-W145516

Guar gum		Thickeners Suspending Agents
Guar gum is an orally active nonionic galactomannan polysaccharide. It is present in the endosperm of Cyamopsis tetragonolobus seeds. Guar gum reduces cholesterol levels, regulates body weight, and acts as a thickener and viscosity modifier by forming hydrogen-bonded aqueous solutions. It serves as a rate-controlling excipient in compound delivery systems, and finds applications in the food, tissue engineering, nanosensing and industrial fields .

HY-Y0850N

Polyvinyl alcohol (Mw 13000-23000, 98% hydrolyzed) 3 Publications Verification PVA (Mw 13000-23000, 98% hydrolyzed); Poly(Ethenol) (Mw 13000-23000, 98% hydrolyzed)		Polymers
Polyvinyl alcohol (PVA; Poly(Ethenol)) (Mw 13000-23000, 98% hydrolyzed) , also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. Polyvinyl alcohol (Mw 13000-23000, 98% hydrolyzed) can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics. Polyvinyl alcohol (Mw 13,000–23,000, 98% hydrolyzed) can be used in studies involving breast cancer as well as cisplatin (HY-17394)-induced sensorineural hearing loss .

HY-W129593

Sorbitan monooctadecanoate Sorbitan monostearate		Emulsifiers Solubilizing Agents Surfactants Suspending Agents
Sorbitan monooctadecanoate (Sorbitan monostearate) is a hydrophobic nonionic surfactant. Sorbitan monooctadecanoate can serve as a pharmaceutical excipient, such as an emulsifier, nonionic surfactant, solubilizer, wetting agent, and dispersing/suspending agent .

HY-101530B

Polyoxyl 40 stearate PEG 40 stearate		Emulsifiers Bases Solubilizing Agents
Polyoxyl 40 stearate (PEG 40 stearate) is a nonionic surfactant formed by the esterification of stearic acid with polyethylene glycol (PEG) containing approximately 40 ethoxy units, it is widely used in pharmaceutical preparations, nanodrug carriers, emulsification systems and biomedical materials. Polyoxyl 40 stearate can serve as a matrix component of solid lipid nanoparticles to achieve controlled release of encapsulated antifungal drugs; it can also act as a base material for solid lipid nanoparticles for vaginal administration, and polymerizable groups can be introduced via modification with acryloyl chloride .

HY-W129513

Sorbitan monopalmitate		Emulsifiers Surfactants
Sorbitan monopalmitate is a food-grade, non-ionic emulsifier that exhibits oral activity. Sorbitan monopalmitate functions as a crystallization modifier, promoting the aggregation of spherical mango butter crystals, introducing lattice defects, and regulating the crystallization rate of mango butter. Sorbitan monopalmitate serves as a component of precursor vesicle gels, enabling the controlled and sustained release of drugs and facilitating the preparation of stable transdermal delivery formulations .

HY-W099536

PEG 4 lauryl ether Tetraoxyethylene glycol monododecyl ether		Solvents
PEG-4 lauryl ether is a non-ionic detergent that can be used as an excipient or for the isolation of functional membrane complexes .

HY-W115716

Sorbitan trioleate Span 85		Emulsifiers Thickeners Surfactants
Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD≥200 mg/kg). Sorbitan trioleate can be used as an excipient, such as surfactant, emulsifier, lubricant, wetting agent, dispersant, thickener, defoamer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-W131101

Sorbitan tristearate		Emulsifiers
Sorbitan tristearate is a non-ionic surfactant, with a synergistic effect on skin permeability. Sorbitan tristearate can be used as an excipient, such as emulsifier. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

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