2. Anti-infection
  3. Influenza Virus
  4. Octaethylene glycol monododecyl ether

Octaethylene glycol monododecyl ether  (Synonyms: C12E8)

Cat. No.: HY-138941 Purity: ≥98.0%
COA Handling Instructions

Octaethylene glycol monododecyl ether (C12E8) is an non-ionic detergent that can be used for membrane protein extraction. Octaethylene glycol monododecyl ether can solubilize the viral membrane of intact influenza virus.

For research use only. We do not sell to patients.

Octaethylene glycol monododecyl ether Chemical Structure

Octaethylene glycol monododecyl ether Chemical Structure

CAS No. : 3055-98-9

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Based on 1 publication(s) in Google Scholar

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Description

Octaethylene glycol monododecyl ether (C12E8) is an non-ionic detergent that can be used for membrane protein extraction. Octaethylene glycol monododecyl ether can solubilize the viral membrane of intact influenza virus[1][2].

In Vitro

Octaethylene glycol monododecyl ether (C12E8) has been shown to solubilize the viral membrane of intact influenza virus. The mechanism of solubilization of the viral membrane is based on the accumulation of C12E8 molecules outside the membrane until the formation of micelles leading to the extraction of membrane constituents[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

538.75

Appearance

Oil

Formula

C28H58O9
CAS No.
SMILES

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (185.61 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8561 mL 9.2807 mL 18.5615 mL
5 mM 0.3712 mL 1.8561 mL 3.7123 mL
10 mM 0.1856 mL 0.9281 mL 1.8561 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (4.64 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (4.64 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.64 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: ≥98.0%

COA (242 KB) HNMR (273 KB) MS (82 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Octaethylene glycol monododecyl ether3055-98-9C12E8Influenza Virusnon-ionicdetergentmembraneproteininfluenzavirusInhibitorinhibitorinhibit

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