1. PROTAC
  2. PROTAC Linker
  3. Dodecaethylene glycol

Dodecaethylene glycol (Synonyms: HO-PEG12-OH)

Cat. No.: HY-141233
Handling Instructions

Dodecaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Dodecaethylene glycol Chemical Structure

Dodecaethylene glycol Chemical Structure

CAS No. : 6790-09-6

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Description

Dodecaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight

546.65

Formula

C₂₄H₅₀O₁₃

CAS No.

6790-09-6

SMILES

OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Dodecaethylene glycolHO-PEG12-OHPROTAC LinkerInhibitorinhibitorinhibit

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Dodecaethylene glycol
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