Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed)
Based on 3 publication(s) in Google Scholar
Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) can be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics, and cosmetics. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A).
For research use only. We do not sell to patients.
- CAS No.: 9002-89-5
- Formula: (C2H4O)n
- Molecular Weight:9000-10000 (Approximately)
-
Storage:
RT, protect from light.
In solvent -80°C, 1 year , -20°C, 6 months
Publications Citing Use of MedChemExpress (MCE) Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed)
More
Biological Activity
Description
In Vitro
Polyvinyl alcohol during in vitro cultivation enables adherent growth on the membrane post PVA degradation with cells still enveloped by PVA after 24 h[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 9002-89-5
-
Appearance Solid
-
Molecular Weight 9000-10000 (Approximately)
-
Formula (C2H4O)n
-
Color White to off-white
-
SMILES
CCC(O)C.[n]
-
Synonyms
PVA (Mw 9000-10000, 80% hydrolyzed); Poly(Ethenol) (Mw 9000-10000, 80% hydrolyzed)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
RT, protect from light
In solvent -80°C 1 year -20°C 6 months
Publications (3)
-
Journal Impact Factor
-
Most Recent
-
Nanoscale Adv
Dexamethasone-loaded lipid-polymeric nanoparticles to improve therapy for cisplatin-induced sensorineural hearing loss. [Abstract]2025 Nov 21. PMID: 41278499 -
-
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 50 mg/mL (Need ultrasonic)
Protocols
-
3D Hydrogel Synthetic Scaffold Culture
3D hydrogel synthetic scaffold culture embeds cells, spheroids, organoids, or tissue fragments inside a hydrated crosslinked polymer network so that cells receive matrix and cell-cell cues in three dimensions rather than from a flat plastic surface. A literature-supported model protocol is PEG-4MAL hydrogel culture, in which four-arm maleimide-terminated PEG is functionalized with cysteine-containing adhesive peptides such as RGD and crosslinked with protease-degradable peptides such as GPQ-W; this creates a defined, modular scaffold that supports human organoid generation and culture. The readouts are scaffold-supported growth, morphology, lumen formation, budding, viability, proliferation, lineage-marker expression, and matrix-dependent expansion or differentiation; reported assays include transmitted-light imaging, immunofluorescence, in situ hybridization, qRT-PCR, and rheological characterization.
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[2]. Türkoğlu, G. C., et al., (2024). PVA-Based Electrospun Materials-A Promising Route to Designing Nanofiber Mats with Desired Morphological Shape-A Review. International journal of molecular sciences, 25(3), 1668. [Content Brief]
[3]. DeMerlis CC, et al. Review of the oral toxicity of polyvinyl alcohol (PVA). Food Chem Toxicol. 2003 Mar;41(3):319-26. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)