HPMC (Type I,Viscosity:100mPa.s)
Based on 1 Customer Validation
HPMC (Type I, Viscosity: 100 mPa·s) is a nonionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs within the hydrated matrix and the polymer relaxation process.
For research use only. We do not sell to patients.
- CAS No.: 9004-65-3
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
The viscosity grade of HPMC significantly affects drug release: low viscosity leads to a faster release rate, while high viscosity results in a slower rate[1].
HPMC is used as an alternative material for hard capsule shells to replace traditional animal-derived gelatin[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9004-65-3
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Appearance Solid
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Color White to off-white
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SMILES
[R]O[C@@H]1[C@H](O[R])[C@@H](O[R])[C@H](O[C@H]2[C@H](O[R])[C@@H](O[R])[C@H](O[R])[C@@H](CO[R])O2)[C@@H](CO[R])O1.CO.CC(O)CO.[n].[x]
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Synonyms
Hypromellose (Type I,Viscosity:100mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:100mPa.s); Celacol HPM 5000 (Type I,Viscosity:100mPa.s)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
H2O : 20 mg/mL (ultrasonic and warming and heat to 60°C)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HPMC (Type I,Viscosity:100mPa.s) Related Classifications
HY-A0104B Related Classifications
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- HPMC (Type I,Viscosity:100mPa.s)
- 9004-65-3
- Hypromellose (Type I,Viscosity:100mPa.s)
- (Hydroxypropyl)methyl cellulose (Type I,Viscosity:100mPa.s)
- Celacol HPM 5000 (Type I,Viscosity:100mPa.s)
- Environmental Pollutants
- Biochemical Assay Reagents
- beta radiation
- Eudragit L acrylic polymers
- cellulose derivative
- non-Fickian transport
- oral controlled-release dosage forms
- hard gelatin capsules
- gamma radiation
- Eudragit S 12.5 acrylic polymers
- plant-derived two-piece hard capsule shell
- hydrophilic polymer
- Inhibitor
- inhibitor
- inhibit