HPMC (Type II,Viscosity:5mPa.s)
Based on 1 Customer Validation
HPMC (Hypromellose) (Type II,Viscosity:5mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. HPMC (Type II,Viscosity:5mPa.s) is widely used in agent formulations due to its biocompatibility, uncharged nature, solubility in water and thermoplastic behavior.
For research use only. We do not sell to patients.
- CAS No.: 9004-65-3
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
HPMC(Type II,Viscosity:5mPa.s) provides the release of a drug in a controlled manner, effectively increasing the duration of release of a drug to prolong its therapeutic effect[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9004-65-3
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Appearance Solid
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Color White to light yellow
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SMILES
[R]O[C@@H]1[C@H](O[R])[C@@H](O[R])[C@H](O[C@H]2[C@H](O[R])[C@@H](O[R])[C@H](O[R])[C@@H](CO[R])O2)[C@@H](CO[R])O1.CO.CC(O)CO.[n].[x]
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Synonyms
Hypromellose (Type II,Viscosity:5mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:5mPa.s); Celacol HPM 5000 (Type II,Viscosity:5mPa.s)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 100 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Handling Instructions (2659 KB)
References
[1]. Li CL, Martini LG, Ford JL, Roberts M. The use of hypromellose in oral drug delivery. J Pharm Pharmacol. 2005 May;57(5):533-46. [Content Brief]
[2]. Tundisi LL, et al. Hydroxypropyl methylcellulose: Physicochemical properties and ocular drug delivery formulations. Eur J Pharm Sci. 2021 Apr 1;159:105736. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- HPMC (Type II,Viscosity:5mPa.s)
- 9004-65-3
- Hypromellose (Type II,Viscosity:5mPa.s)
- (Hydroxypropyl)methyl cellulose (Type II,Viscosity:5mPa.s)
- Celacol HPM 5000 (Type II,Viscosity:5mPa.s)
- Environmental Pollutants
- Biochemical Assay Reagents
- Hydroxypropyl methylcellulose
- Ocular drug delivery
- Ocular formulations
- Inhibitor
- inhibitor
- inhibit