HPMC (Type II,Viscosity:3mPa.s)
Based on 1 Customer Validation
HPMC (Type II, Viscosity: 3 mPa.s) is a nonionic polymer prepared via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, which includes the diffusion of drugs in the hydrated matrix and the polymer relaxation process.
For research use only. We do not sell to patients.
- CAS No.: 9004-65-3
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
The viscosity grade of HPMC significantly affects drug release: lower viscosity leads to faster release, while higher viscosity results in slower release[1].
HPMC is used as an alternative material for hard capsule shells to replace traditional animal-derived gelatin[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9004-65-3
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Appearance Solid
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Color White to off-white
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SMILES
[R]O[C@@H]1[C@H](O[R])[C@@H](O[R])[C@H](O[C@H]2[C@H](O[R])[C@@H](O[R])[C@H](O[R])[C@@H](CO[R])O2)[C@@H](CO[R])O1.CO.CC(O)CO.[n].[x]
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Synonyms
Hypromellose (Type II,Viscosity:3mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:3mPa.s); Celacol HPM 5000 (Type II,Viscosity:3mPa.s)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
H2O : 20 mg/mL (ultrasonic and warming and heat to 60°C)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- HPMC (Type II,Viscosity:3mPa.s)
- 9004-65-3
- Hypromellose (Type II,Viscosity:3mPa.s)
- (Hydroxypropyl)methyl cellulose (Type II,Viscosity:3mPa.s)
- Celacol HPM 5000 (Type II,Viscosity:3mPa.s)
- Environmental Pollutants
- Biochemical Assay Reagents
- drug release prolonger
- solid dispersion excipient
- cellulose-derived synthetic polymer
- bioadhesive
- non-Fickian transport
- coating polymer
- hydrophilic matrix former
- thickening agent
- hydrated matrices
- polymer relaxation
- Inhibitor
- inhibitor
- inhibit