4-tert-Octylphenol monoethoxylate
Based on 1 Customer Validation
4-tert-Octylphenol monoethoxylate is an alkylphenolethoxylate (APE) and a degradation product of non-ionic surfactants (such as 4-tert-octylphenol polyethoxylate). 4-tert-Octylphenol monoethoxylate also possesses non-steroidal estrogenic activity. Additionally, 4-tert-Octylphenol monoethoxylate has been found in wastewater effluent.
For research use only. We do not sell to patients.
- Purity: 98.97%
- CAS No.: 2315-67-5
- Formula: C16H26O2
- Molecular Weight:250.38
-
Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Chemical Information
-
CAS No. 2315-67-5
-
Appearance Oil
-
Molecular Weight 250.38
-
Formula C16H26O2
-
Color Colorless to light yellow
-
SMILES
OCCOC1=CC=C(C(C)(CC(C)(C)C)C)C=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (399.39 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (9.98 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (9.98 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
-
%+
-
+%Tween-80 + +
-
%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (600 KB)
- English - EN (600 KB)
- Français - FR (600 KB)
- Deutsch - DE (600 KB)
- Norwegian - NO (600 KB)
- Español - ES (600 KB)
- Swedish - SV (600 KB)
- Italian - IT (600 KB)
- Korean - KR (600 KB)
- Portuguese - PT (600 KB)
-
Handling Instructions (2659 KB)
References
[1]. Vajda AM, et al. Reproductive disruption in fish downstream from an estrogenic wastewater effluent. Environ Sci Technol. 2008 May 1;42(9):3407-14. [Content Brief]
[2]. Nishio E, et al. Isolation and identification of Sphingomonas sp. that yields tert-octylphenol monoethoxylate under aerobic conditions. Biosci Biotechnol Biochem. 2005 Jul;69(7):1226-31. [Content Brief]
[3]. Barber LB, et al. Reproductive responses of male fathead minnows exposed to wastewater treatment plant effluent, effluent treated with XAD8 resin, and an environmentally relevant mixture of alkylphenol compounds. Aquat Toxicol. 2007 Apr 20;82(1):36-46. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9939 mL | 19.9696 mL | 39.9393 mL | 99.8482 mL |
| 5 mM | 0.7988 mL | 3.9939 mL | 7.9879 mL | 19.9696 mL | |
| 10 mM | 0.3994 mL | 1.9970 mL | 3.9939 mL | 9.9848 mL | |
| 15 mM | 0.2663 mL | 1.3313 mL | 2.6626 mL | 6.6565 mL | |
| 20 mM | 0.1997 mL | 0.9985 mL | 1.9970 mL | 4.9924 mL | |
| 25 mM | 0.1598 mL | 0.7988 mL | 1.5976 mL | 3.9939 mL | |
| 30 mM | 0.1331 mL | 0.6657 mL | 1.3313 mL | 3.3283 mL | |
| 40 mM | 0.0998 mL | 0.4992 mL | 0.9985 mL | 2.4962 mL | |
| 50 mM | 0.0799 mL | 0.3994 mL | 0.7988 mL | 1.9970 mL | |
| 60 mM | 0.0666 mL | 0.3328 mL | 0.6657 mL | 1.6641 mL | |
| 80 mM | 0.0499 mL | 0.2496 mL | 0.4992 mL | 1.2481 mL | |
| 100 mM | 0.0399 mL | 0.1997 mL | 0.3994 mL | 0.9985 mL |
4-tert-Octylphenol monoethoxylate Related Classifications
HY-W338581 Related Classifications
Powered by Bioz