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  4. 2-(Dodecyloxy)ethanol

2-(Dodecyloxy)ethanol  (Synonyms: Ethylene glycol monododecyl ether)

Cat. No.: HY-W250300
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2-(Dodecyloxy) ethanol (Ethylene glycol monododecyl ether) is a nonionic ether monohydroxy C12 surfactant with a fragrance-like odor similar to jasmone and gardenia. 2-(Dodecyloxy) ethanol acts as a phase transition inducer and micelle-forming agent. 2-(Dodecyloxy) ethanol also serves as a skin penetration enhancer.

For research use only. We do not sell to patients.

2-(Dodecyloxy)ethanol

2-(Dodecyloxy)ethanol Chemical Structure

CAS No. : 4536-30-5

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Other Forms of 2-(Dodecyloxy)ethanol:

2-(Dodecyloxy)ethanol Related Antibodies

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Description

2-(Dodecyloxy) ethanol (Ethylene glycol monododecyl ether) is a nonionic ether monohydroxy C12 surfactant with a fragrance-like odor similar to jasmone and gardenia. 2-(Dodecyloxy) ethanol acts as a phase transition inducer and micelle-forming agent. 2-(Dodecyloxy) ethanol also serves as a skin penetration enhancer[1][2][3].

In Vitro

2-(Dodecyloxy) ethanol (0.16 M; 1 h) enhances the passive transdermal penetration of Ondansetron hydrochloride (HY-B0002) and Diltiazem hydrochloride (HY-14656) through stripped pig skin[3].
2-(Dodecyloxy) ethanol (0.16 M; 1 h) enhances iontophoresis and post-iontophoretic transdermal penetration of ondansetron hydrochloride and diltiazem hydrochloride through stripped porcine skin[3].
2-(Dodecyloxy) ethanol (0.016-160 μM; 24 h) is toxic to cultured human epidermal keratinocytes and reduces the viability of cultured human dermal fibroblasts to approximately 35%[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-(Dodecyloxy)ethanol Related Antibodies

Cell Cytotoxicity Assay[3]

Cell Line: Human epidermal keratinocytes (HEK)
Concentration: 0.016-160 μM
Incubation Time: 24 h
Result: Was lethal to all HEK at 160 μM.
Did not reduce HEK viability significantly at 16 μM.
Did not cause a significant decrease in HEK viability at concentrations of 1.6 μM or lower.

Cell Cytotoxicity Assay[3]

Cell Line: Human dermal fibroblasts (HDF)
Concentration: 0.016-160 μM
Incubation Time: 24 h
Result: Reduced HDF viability to approximately 35% at 160 μM.
Did not cause a significant decrease in HDF viability at concentrations of 16 μM or lower.
Molecular Weight

230.39

Formula

C14H30O2
CAS No.
SMILES

OCCOCCCCCCCCCCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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2-(Dodecyloxy)ethanol Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-(Dodecyloxy)ethanol4536-30-5Ethylene glycol monododecyl etherBiochemical Assay Reagentssurfactantskin penetration enhancerInhibitorinhibitorinhibit

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