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Cat. No.: HY-125861H

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Methyl cellulose(Viscosity:25mPa.s)

(Synonyms: MC(Viscosity:25mPa.s))

Methyl cellulose (MC) (Viscosity:25mPa.s) is a non-ionic cellulose ether with surface activity and thermogelation properties. Methyl cellulose (Viscosity:25mPa.s) is widely used as drug delivery agents, thickeners, stabilizers, emulsifiers, etc., in industries such as pharmaceuticals, food, cosmetics, and construction.

For research use only. We do not sell to patients.

CAS No.: 9004-67-5

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Methyl cellulose(Viscosity:25mPa.s) Chemical Structure

CAS No.: 9004-67-5

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Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vivo

Methyl cellulose (0.5%; intraperitoneal injection/oral administration; twice weekly; 6 weeks) (Viscosity:25mPa.s) causes systemic tissue lesions via intraperitoneal injection, while oral administration exhibits good safety in CF-1 mice^[1].
NOTE:
1. No solid-liquid separation occurs in the Methyl cellulose solution. The solution is uniformly transparent without particles.
2. Complete dissolution of Methyl cellulose may require 4 hours or longer.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

CF-1 mice aged 3 weeks old (12-14 g) underwent corneal kindling (electrical stimulation to induce chronic seizures) or sham kindling (handling without stimulation)^[1]
Dosage:

5%
Administration:

Intraperitoneal (i.p.) or oral (p.o.) administration, twice weekly for 6 weeks
Result:

Led to widespread accumulation of foam-laden macrophages in multiple tissues (kidney, liver, mesentery, aorta, choroid plexus) with associated inflammation and occasional tissue damage in both kindled and sham mice by i.p..
Caused no histologic lesions by p.o..
Had no significant effects on body weight, seizure stability, behavioral assessments (open field test), hematology, or serum biochemistry parameters.

Chemical Information

CAS No. 9004-67-5
SMILES

[Methyl cellulose(Viscosity:25mPa.s)]
Synonyms

MC(Viscosity:25mPa.s)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Stacey Meeker, et al. Repeated Intraperitoneal Administration of Low-Concentration Methylcellulose Leads to Systemic Histologic Lesions Without Loss of Preclinical Phenotype. J Pharmacol Exp Ther. 2019 Oct;371(1):25-35. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Methyl cellulose(Viscosity:25mPa.s)

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Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References

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Methyl cellulose(Viscosity:25mPa.s)

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Methyl cellulose(Viscosity:25mPa.s) Related Classifications

HY-125861H Related Classifications