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Results for "

amino acid amide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (2) EAAT (1) ADC Linker (1) Amylin Receptor (2) Apoptosis (4) Bacterial (3) Biochemical Assay Reagents (72) c-Met/HGFR (1) Caspase (1) DNA/RNA Synthesis (3) Drug Intermediate (3) Endogenous Metabolite (13) Endothelin Receptor (1) Environmental Pollutants (1) Ferroptosis (5) Fluorescent Dye (17) iGluR (1) Isotope-Labeled Compounds (7) Liposome (4) Melanocortin Receptor (2) mGluR (5) Microtubule/Tubulin (1) Mitosis (1) Na+/K+ ATPase (7) PROTAC Linkers (20) Radionuclide-Drug Conjugates (RDCs) (1) Reactive Oxygen Species (ROS) (2) Reference Standards (4) Ser/Thr Protease (1)
By Research Areas:	Cancer (34) Cardiovascular Disease (4) Endocrinology (2) Infection (5) Inflammation/Immunology (1) Metabolic Disease (13) Neurological Disease (15)
Oligonucleotides:	Pegylated Lipids (4) Cationic Lipids (1) Polymers (1)

151

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: FAAH Amino Acid Decarboxylase Amino Acid Oxidase Amino Acid Derivatives Amino acid Transporter Branched Chain Amino Acid Transaminase (BCAT) EAAT

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0390

L-Glutamine 25+ Cited Publications L-Glutamic acid 5-amide	Environmental Pollutants Endogenous Metabolite mGluR Ferroptosis	Metabolic Disease Cancer
L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells .

HY-15121

L-Theanine 5 Publications Verification L-Glutamic acid γ-ethyl amide; Nγ-Ethyl-L-glutamine	Apoptosis Endogenous Metabolite Reactive Oxygen Species (ROS)	Neurological Disease Cancer
L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through the blood–brain barrier and is orally active .

HY-79647

Fmoc-OSu N-(Fmoc-oxy)succinimide	Biochemical Assay Reagents	Others
Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .

HY-P1070A

Amylin, amide, human TFA DAP amide, human TFA	Amylin Receptor	Metabolic Disease
Amylin, amide, human TFA, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human TFA inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent .

HY-16969

Dihexa 5+ Cited Publications PNB-0408; N-hexanoic-Try-Ile-(6)-amino hexanoic amide; Hexanoyl-Tyr-Ile-Ahx-NH2	c-Met/HGFR	Neurological Disease
Dihexa, an oligopeptide drug, is an orally active and blood-brain barrier-permeable angiotensin IV analog. Dihexa binds to hepatocyte growth factor (HGF) with high affinity (K_d=65 pM) and potentiates its activity at its receptor, c-Met. Dihexa exhibits excellent antidementia activity and improves cognitive function in animal models. Dihexa may have therapeutic potential as a treatment Alzheimer’s disease .

HY-P1070

Amylin, amide, human DAP amide, human	Amylin Receptor	Metabolic Disease
Amylin, amide, human, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent .

HY-Y0973

BOP hexafluorophosphate	Biochemical Assay Reagents Drug Intermediate	Others
BOP hexafluorophosphate is a phosphonium-type condensing agent. BOP hexafluorophosphate activates the carboxylic acid component to form a highly reactive O-benzotriazole ester (active ester) intermediate, which then reacts with the amino component to form an amide bond (peptide bond). BOP hexafluorophosphate is applicable to solid-phase polypeptide synthesis and nucleoside modification .

HY-B0137

Prilocaine 1 Publications Verification	Na+/K+ ATPase	Neurological Disease
Prilocaine, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects .

HY-W088929

H-Glu(OtBu)-NH2 hydrochloride	Amino Acid Derivatives	Others
H-Glu(OtBu)-NH2 hydrochloride is a specialized amino acid derivative that is crucial for the synthesis of peptides bearing a C-terminal glutamine amide.

HY-D1085

AMCA-X SE	Fluorescent Dye	Others
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .

HY-120957

AMC Arachidonoyl Amide AMC-AA; 7-amino-4-methyl coumarin-arachidonamide	Endogenous Metabolite	Metabolic Disease
AMC arachidonoyl amide (AMC-AA) is one of several fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.1 FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its nominal endogenous substrate anandamide.2 Exposure of AMC-AA to FAAH activity results in the release of the fluorescent aminomethyl coumarin that absorbs at 360 nm and emits at 465 nm. This allows the fast and convenient measurement of FAAH activity using a simple cuvette or microplate fluorometer.

HY-W008559

L-Tyrosinamide	Endogenous Metabolite	Metabolic Disease
L-Tyrosinamide is a derivative of Tyrosine, is an amino acid amide .

HY-P1531

γ-1-Melanocyte Stimulating Hormone (MSH), amide	Melanocortin Receptor	Cardiovascular Disease Metabolic Disease Endocrinology
γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na ⁺) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

HY-174921A

Maleimide-PEG2000-COOH	Biochemical Assay Reagents	Others
Maleimide-PEG2000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .

HY-157745

m-PEG40000-NHS ester mPEG40000-SC; mPEG40000-Succinimidyl ester	Biochemical Assay Reagents	Others
m-PEG-NHS ester (mPEG-SC; mPEG-Succinimidyl ester) (MW 40000) is a polyethylene glycol derivative. m-PEG-NHS ester serves as a modifying agent that reacts with free amino groups on the surface of protein or polypeptide molecules to form stable amide bonds, thereby covalently linking PEG chains to biomacromolecules, improving their antigenicity and immunogenicity, and facilitating the preparation of injectable formulations .

HY-169794

N-Palmitoyl-phenylalanine	DNA/RNA Synthesis	Others
N-Palmitoyl-phenylalanine is an N-acyl amide that contains the long-chain saturated fatty acid Palmitic acid (HY-N0830) conjugated via an amide bond to the essential amino acid L-Phenylalanine (HY-N0215). N-Palmitoyl-phenylalanine inhibits pre-mRNA splicing in HeLa cell nuclear lysates (IC₅₀ ＞ 400 μM) but has no splicing activity in intact HeLa cells .

HY-W041856

N-Boc-8-amino-octanoic acid Boc-8-aminooctanoic acid	PROTAC Linkers	Cancer
N-Boc-8-amino-octanoic acid (Boc-8-aminooctanoic acid) can be used as a PROTAC linker in the synthesis of PROTACs. N-Boc-8-amino-octanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

HY-W1048918A

mPEG5000-CM mPEG5000-COOH	Biochemical Assay Reagents	Others
mPEG5000-CM (mPEG5000-COOH) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG5000-CM can be used for drug delivery .

HY-W1123939C

Silane-PEG5000-COOH	Biochemical Assay Reagents	Others
Silane-PEG5000-COOH can be used to modify proteins, peptides and other materials with active groups. The carboxyl group (-COOH) can easily form a stable amide bond with the amino group, and can also form an ester bond with the hydroxyl group. Silane-functionalized PEG (Silane-PEG-X) can be used to modify glass, silicon, etc .

HY-W1048525

8-Arm PEG5000-NH2 8-Arm PEG5000-Amine	Biochemical Assay Reagents	Others
8-Arm PEG5000-NH2 (8-Arm PEG5000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-140249

*Tri(Amino-PEG3-amide)-amine*	PROTAC Linkers	Cancer
Tri(Amino-PEG3-amide)-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-P2736

Amidase	Endogenous Metabolite	Metabolic Disease
Amidases, a member of nitrilase superfamily, catalyzes the hydrolysis of an amide, leading to the formation of carboxylic acid and ammonia. Amidases contain a conserved stretch of approximately 130 amino acids known as the AS sequence, and play a role in important metabolic processes .

HY-W005828

9-(Boc-amino)nonanoic acid	PROTAC Linkers	Cancer
9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. 9-(Boc-amino)nonanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

HY-W009056

Fmoc-7-amino-heptanoic acid	PROTAC Linkers	Cancer
Fmoc-7-amino-heptanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. Fmoc-7-amino-heptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

HY-15121S1

L-Theanine-13C2,15N2 L-Glutamic acid γ-ethyl amide-¹³C₂,¹⁵N₂; Nγ-Ethyl-L-glutamine-¹³C₂,¹⁵N₂	DNA/RNA Synthesis	Others
L-Theanine- ¹³C₂, ¹⁵N₂ (L-Glutamic Acid γ-ethyl amide- ¹³C₂, ¹⁵N₂) is the ¹³C- and ¹⁵N-labeled L-Theanine (HY-15121). L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through the blood–brain barrier and is orally active.

HY-W105727

9-Aminononanoic acid	PROTAC Linkers	Cancer
9-Aminononanoic acid can be used as a PROTAC linker and other conjugation in the synthesis of PROTACs. 9-Aminononanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.

HY-140251

*Tri(Amino-PEG5-amide)-amine*	PROTAC Linkers	Cancer
Tri(Amino-PEG5-amide)-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-P4332

Boc-Glu(OBzl)-Ala-Arg-AMC	Fluorescent Dye Ser/Thr Protease	Cardiovascular Disease
Boc-Glu(OBzl)-Ala-Arg-AMC is a fluorogenic substrate for coagulation factor XIa and trypsin. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .

HY-B0137A

Prilocaine hydrochloride 1 Publications Verification	Na+/K+ ATPase	Neurological Disease
Prilocaine hydrochloride, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects .

HY-N0390S10

L-Glutamine-1,2-13C2 L-Glutamic acid 5-amide-1,2-¹³C₂	Isotope-Labeled Compounds mGluR Endogenous Metabolite Ferroptosis	Metabolic Disease Cancer
L-Glutamine-1,2- ¹³C₂ is the ¹³C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells .

HY-130695

N-(Amino-PEG5)-N-bis(PEG4-acid)	ADC Linker	Cancer
N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG derivative containing an amino group with two terminal carboxylic acids. The amino group is reactive with carboxylic acids, activated NHS esters. The terminal carboxylic acids can react with primary amine groups in the presence of activators to form a stable amide bond. N-(Amino-PEG5)-N-bis(PEG4-acid) can be useful in the development of antibody drug conjugates (ADCs) .

HY-W011118

DTPA anhydride	Radionuclide-Drug Conjugates (RDCs)	Cancer
DTPA anhydride is a bifunctional chelator whose anhydride can react with amino groups in proteins (such as lysine residues) to form stable amide bonds. DTPA anhydride can also bind to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs). RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy.

HY-N0390S15

L-Glutamine-d4 L-Glutamic acid 5-amide-d₄	Isotope-Labeled Compounds mGluR Endogenous Metabolite Ferroptosis	Metabolic Disease Cancer
L-Glutamine-d₄ (L-Glutamic acid 5-amide-d₄) is the deuterium labeled L-Glutamine (HY-N0390). L-Glutamine is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells .

HY-140250

*Tri(Amino-PEG4-amide)-amine*	PROTAC Linkers	Cancer
Tri(Amino-PEG4-amide)-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-133883

Cyanine7.5 amine	Fluorescent Dye	Others
Cyanine7.5 amine is a near-infrared Cy7.5-based dye and also a substrate for amide bond coupling (Ex/Em = 788 nm/808 nm). Cyanine7.5 amine contains a free amino group and can be used for coupling with activated carboxylic acid derivatives .

HY-140250A

*Tri(Amino-PEG4-amide)-amine TFA*	PROTAC Linkers	Cancer
Tri(Amino-PEG4-amide)-amine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-140249A

*Tri(Amino-PEG3-amide)-amine TFA*	PROTAC Linkers	Cancer
Tri(Amino-PEG3-amide)-amine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-P4333

Boc-Glu(OBzl)-Gly-Arg-AMC	Fluorescent Dye	Cardiovascular Disease
Boc-Glu(OBzl)-Gly-Arg-AMC is a fluorogenic substrate for factors IXa and XIIa. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .

HY-B0137B

Prilocaine acetate	Na+/K+ ATPase	Neurological Disease
Prilocaine acetate, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine acetate has neurotoxic effects .

HY-W097355

(R)-2-Amino-3-phenylpropanamide D-Phenylalanine amide; H-D-Phe-NH2	Amino Acid Derivatives Drug Intermediate	Cancer
(R)-2-Amino-3-phenylpropanamide (D-Phenylalanine amide) is a non-natural D-α-amino acid derivative and chiral amino acid amide. (R)-2-Amino-3-phenylpropanamide can be converted into D-Phenylalanine (HY-Y0079), which is applicable to the construction of all-D antimicrobial peptides and the synthesis of anti-HIV reagents. (R)-2-Amino-3-phenylpropanamide serves as a reagent for synthesizing benzoxaborole derivative 6, a dual covalent binder of Pseudomonas aeruginosa PBP3. (R)-2-Amino-3-phenylpropanamide is used in colon cancer-related research .

HY-157921

Amino-EG6-undecanethiol hydrochloride 20-(9-Mercaptononyl)-3,6,9,12,15,18-hexaoxaeicosane-1-amine, hydrochloride	Biochemical Assay Reagents	Others
Amino-EG6-undecanethiol hydrochloride is a biochemical assay reagent, and can be used as a linker through amide coupling .

HY-B0137AS

Prilocaine-d7 hydrochloride	Isotope-Labeled Compounds Na+/K+ ATPase	Neurological Disease
Prilocaine-d₇ (hydrochloride) is deuterium labeled Prilocaine (hydrochloride). Prilocaine hydrochloride, an amino amide, is a Na, K-ATPase inhibitor. Prilocaine has neurotoxic effects .

HY-135717

Norbiotinamine	Biochemical Assay Reagents	Cancer
Norbiotinamine is an alternative to biotin. Norbiotinamine can be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction .

HY-135717A

Norbiotinamine hydrochloride	Biochemical Assay Reagents	Cancer
Norbiotinamine hydrochloride is an alternative to biotin. Norbiotinamine can be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction .

HY-N0390S11

L-Glutamine-2-13C L-Glutamic acid 5-amide-2-¹³C	Isotope-Labeled Compounds mGluR Endogenous Metabolite Ferroptosis	Metabolic Disease
L-Glutamine-2- ¹³C is the ¹³C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells .

HY-B0137R

Prilocaine (Standard)	Reference Standards Na+/K+ ATPase	Neurological Disease
Prilocaine (Standard) is the analytical standard of Prilocaine. This product is intended for research and analytical applications. Prilocaine, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects .

HY-B0137AR

Prilocaine hydrochloride (Standard)	Reference Standards Na+/K+ ATPase	Neurological Disease
Prilocaine (hydrochloride) (Standard) is the analytical standard of Prilocaine (hydrochloride). This product is intended for research and analytical applications. Prilocaine hydrochloride, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects .

HY-100801R

L-threo-3-Hydroxyaspartic acid (Standard)	EAAT Reference Standards	Neurological Disease
Prilocaine (hydrochloride) (Standard) is the analytical standard of Prilocaine (hydrochloride). This product is intended for research and analytical applications. Prilocaine hydrochloride, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects .

HY-P5483

Retro-indolicidin	Bacterial	Others
Retro-indolicidin is a biological active peptide. (Reverse peptide of indolicidin (Rev4) is a 13-amino acid residue peptide based on the sequence of indolicidin. Indolicidin, a member of the cathelicidin protein family, is a 13-amino acid residue cationic, antimicrobial peptide-amide isolated from the cytoplasmic granules of bovine neutrophils. The synthetic peptide Rev4 has been shown to possess strong antimicrobial as well as protease inhibitory activities in vitro.)

HY-49053

N-Boc-dolaproine-amide-Me-Phe	Microtubule/Tubulin Mitosis	Cancer
N-Boc-dolaproine-amide-Me-Phe is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity .

Cat. No.	Product Name

HY-L907

MCE Kinase Hinge Binder Fragment Library

12,412 compounds

The most prominent mechanism of action of kinase inhibitors is their competition with ATP by binding to the hinge region of the kinase protein. Once the kinase is blocked by an inhibitor, it loses the ability to transfer phosphate groups from ATP to other molecules, resulting in the loss of kinase activity.

The hinge-binding region of kinase inhibitors mimics the interaction pattern between the ATP nucleobase and the kinase. MCE extracted thousands of kinase inhibitors from the ChEMBL database and isolated their molecular fragments. In certain cases, the amino and amide groups on the molecular fragments are crucial for binding in the hinge region. Therefore, we enhanced the diversity of the collected results by adding these two groups to unoccupied positions on the ring system. Subsequently, the fragments were assessed for their hinge region binding ability via docking at distinct kinases, we also applied pharmacophore constraints to ensure interactions with key amino acids in the kinase hinge region, ultimately obtaining kinase-related molecular fragments.

MCE provides over 12,412 kinase fragment molecules that meet the above requirements and are available off the shelf, serving as an effective tool for screening and developing drugs targeting kinases.

Cat. No.	Product Name	Type

HY-D1085

AMCA-X SE	Fluorescent Dyes
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .

HY-133883

Cyanine7.5 amine	Fluorescent Dyes
Cyanine7.5 amine is a near-infrared Cy7.5-based dye and also a substrate for amide bond coupling (Ex/Em = 788 nm/808 nm). Cyanine7.5 amine contains a free amino group and can be used for coupling with activated carboxylic acid derivatives .

HY-D2895A

RB-PEG600-NH2 Rhodamine B-PEG600-NH2	Fluorescent Dyes
RB-PEG600-NH2 (Rhodamine B-PEG600-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D2895H

RB-PEG10000-NH2 Rhodamine B-PEG10000-NH2	Fluorescent Dyes
RB-PEG10000-NH2 (Rhodamine B-PEG10000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D2895D

RB-PEG3400-NH2 Rhodamine B-PEG3400-NH2	Fluorescent Dyes
RB-PEG3400-NH2 (Rhodamine B-PEG3400-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D2895B

RB-PEG1000-NH2 Rhodamine B-PEG1000-NH2	Fluorescent Dyes
RB-PEG1000-NH2 (Rhodamine B-PEG1000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D2895

RB-PEG400-NH2 Rhodamine B-PEG400-NH2	Fluorescent Dyes
RB-PEG400-NH2 (Rhodamine B-PEG400-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D3389

sCy5DL-amide

Fluorescent Dyes

sCy5DL-amide is an amidated fluorescent D-amino acid conjugated to Sulfo-Cyanine 5, and a peptidoglycan labeling agent. sCy5DL-amide incorporates into bacterial peptidoglycan cell wall via transpeptidase-mediated reactions, replacing the fourth or fifth D-amino acid of the peptidoglycan stem peptide for visualization of nascent peptidoglycan biosynthesis. sCy5DL-amide produces clear cell outline, septum labeling, and high localization density in Bacillus subtilis, including a 'V-shape' pattern at cell-cell contact areas. sCy5DL-amide exhibits robust incorporation into Gram-positive bacteria and mycobacteria, with reduced incorporation into Gram-negative bacteria (Ex/Em = 646/666 nm) .

HY-D3049

5(6)-carbonylated rhodamine 110 NHS ester	Fluorescent Dyes
5(6)-carbonylated rhodamine 110 NHS ester is a reactive ester fluorescent reagent based on 5(6)-carbonylated rhodamine 110. NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 502/527 nm).

HY-D3050

5(6)-carbonylated rhodamine 110 X NHS ester	Fluorescent Dyes
5(6)-carbonylated rhodamine 110 X NHS ester is a reactive ester fluorescent reagent based on 5(6)-carbonylated rhodamine 110 X. NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 496/522 nm).

HY-D3053

5(6)-Rhodamine 6G NHS ester	Fluorescent Dyes
5(6)-Rhodamine 6G NHS ester is a reactive ester fluorescent reagent based on Rhodamine 6G (HY-D0309). NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 526/547 nm).

HY-D2895E

RB-PEG5000-NH2 Rhodamine B-PEG5000-NH2	Fluorescent Dyes
RB-PEG5000-NH2 (Rhodamine B-PEG5000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

HY-D2895C

RB-PEG2000-NH2 Rhodamine B-PEG2000-NH2	Fluorescent Dyes
RB-PEG2000-NH2 (Rhodamine B-PEG2000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .

Cat. No.	Product Name	Type

HY-Y0623

N-Hydroxysuccinimide

5+ Cited Publications

HOSu; 1-Hydroxy-2,5-pyrrolidinedione

Biochemical Assay Reagents

N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups (-NH2) to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis (such as collagen, chitosan crosslinking), drug delivery systems (such as hydrogel preparation) and tissue engineering .

HY-79647

Fmoc-OSu

N-(Fmoc-oxy)succinimide

Biochemical Assay Reagents

Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .

HY-Y0973

BOP hexafluorophosphate	Biochemical Assay Reagents
BOP hexafluorophosphate is a phosphonium-type condensing agent. BOP hexafluorophosphate activates the carboxylic acid component to form a highly reactive O-benzotriazole ester (active ester) intermediate, which then reacts with the amino component to form an amide bond (peptide bond). BOP hexafluorophosphate is applicable to solid-phase polypeptide synthesis and nucleoside modification .

HY-W1048558A

mPEG2000-CM

mPEG2000-COOH

Biochemical Assay Reagents

mPEG2000-CM (mPEG2000-COOH) is a carboxyl-terminated monomethoxy polyethylene glycol. mPEG2000-CM bears a reactive carboxyl group (-COOH) at its structural terminal site, which can form stable amide bonds with amino groups and ester bonds with hydroxyl groups. mPEG2000-CM binds to PCA-g-PCL copolymers via electrostatic interaction to form polyion complex micelles with a hydrophilic PEG surface, which enhances the stability of micelles in aqueous media. mPEG2000-CM can be used for drug delivery .

HY-174921A

Maleimide-PEG2000-COOH	Biochemical Assay Reagents
Maleimide-PEG2000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .

HY-W1048918A

mPEG5000-CM mPEG5000-COOH	Biochemical Assay Reagents
mPEG5000-CM (mPEG5000-COOH) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG5000-CM can be used for drug delivery .

HY-W1123939C

Silane-PEG5000-COOH	Biochemical Assay Reagents
Silane-PEG5000-COOH can be used to modify proteins, peptides and other materials with active groups. The carboxyl group (-COOH) can easily form a stable amide bond with the amino group, and can also form an ester bond with the hydroxyl group. Silane-functionalized PEG (Silane-PEG-X) can be used to modify glass, silicon, etc .

HY-W1048525

8-Arm PEG5000-NH2 8-Arm PEG5000-Amine	Biochemical Assay Reagents
8-Arm PEG5000-NH2 (8-Arm PEG5000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048555A

Mal-PEG2000-SCM

Biochemical Assay Reagents

Mal-PEG2000-SCM is a heterobifunctional PEG crosslinker bearing maleimide and succinimidyl carboxymethyl ester functional groups. MMal-PEG2000-SCM conjugates the F3 peptide to nanoparticles: the SCM group reacts with amino groups on the nanoparticle surface to form amide groups, while the MAL group reacts with thiol groups of the F3 peptide to form carbon-sulfur bonds. Mal-PEG-SCM enables unidirectional addition of linkers, ensuring that appropriate functional groups are available for RGD incorporation. Mal-PEG2000-SCM can be used in the development of nanoparticles targeting specific tumor cells .

HY-W190877

Thiol-PEG1-acid SH-PEG1-COOH	Biochemical Assay Reagents
Thiol-PEG1-acid (SH-PEG1-COOH) is a PEG derivative consisting of a thiol (-SH), 1 PEG unit, and a carboxyl (-COOH). The thiol is a highly reactive chemical group that can react specifically with a variety of molecules to form stable covalent bonds. The carboxyl group can easily form stable amide bonds with amino groups, and can also form ester bonds with hydroxyl groups.

HY-157921

Amino-EG6-undecanethiol hydrochloride 20-(9-Mercaptononyl)-3,6,9,12,15,18-hexaoxaeicosane-1-amine, hydrochloride	Biochemical Assay Reagents
Amino-EG6-undecanethiol hydrochloride is a biochemical assay reagent, and can be used as a linker through amide coupling .

HY-172270D

DSPE-PEG5000-Mal-Cys-KTLLPTP	Biochemical Assay Reagents
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

HY-172270

DSPE-PEG1000-Mal-Cys-KTLLPTP	Biochemical Assay Reagents
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

HY-172270A

DSPE-PEG2000-Mal-Cys-KTLLPTP	Biochemical Assay Reagents
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

HY-174921B

Maleimide-PEG3400-COOH	Biochemical Assay Reagents
Maleimide-PEG3400-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .

HY-174921C

Maleimide-PEG5000-COOH	Biochemical Assay Reagents
Maleimide-PEG5000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .

HY-174921

Maleimide-PEG1000-COOH	Biochemical Assay Reagents
Maleimide-PEG1000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .

HY-W1048918

mPEG1000-CM mPEG1000-COOH	Biochemical Assay Reagents
mPEG1000-CM (mPEG1000-COOH) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG1000-CM can be used for drug delivery .

HY-W1123939

Silane-PEG-COOH (MW 1000)	Biochemical Assay Reagents
Silane-PEG-COOH (MW 1000) can be used to modify proteins, peptides and other materials with active groups. The carboxyl group (-COOH) can easily form a stable amide bond with the amino group, and can also form an ester bond with the hydroxyl group. Silane-functionalized PEG (Silane-PEG-X) can be used to modify glass, silicon, etc .

HY-W1048525B

8-Arm PEG40000-NH2 8-Arm PEG40000-Amine	Biochemical Assay Reagents
8-Arm PEG40000-NH2 (8-Arm PEG40000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048526

8-Arm PEG5000-NH2 HCL 8-Arm PEG5000-amine HCL salt	Biochemical Assay Reagents
8-Arm PEG5000-NH2 (8-Arm PEG5000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048526A

8-Arm PEG20000-NH2 HCL 8-Arm PEG20000-amine HCL salt	Biochemical Assay Reagents
8-Arm PEG20000-NH2 (8-Arm PEG20000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W888710D

FA-PEG2000-COOH Folate-PEG2000-COOH	Biochemical Assay Reagents
FA-PEG2000-COOH (Folate-PEG2000-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .

HY-W888710E

FA-PEG3400-COOH Folate-PEG3400-COOH	Biochemical Assay Reagents
FA-PEG3400-COOH (Folate-PEG3400-COOH) is a Folic acid (HY-16637)-modified PEG derivative containing a carboxyl group (-COOH). The carboxyl group can easily form a stable amide bond with an amino group, or an ester bond with a hydroxyl group. Folic acid (-FA) has a high affinity for the folate receptor and can be used to target cell membrane receptors for drug delivery .

HY-172270C

DSPE-PEG3400-Mal-Cys-KTLLPTP	Biochemical Assay Reagents
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

HY-W1048918B

mPEG10000-CM mPEG10000-COOH	Biochemical Assay Reagents
mPEG10000-CM (mPEG10000-COOH) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG10000-CM can be used for drug delivery .

HY-174904

Dde Biotin-PEG4-COOH	Biochemical Assay Reagents
Dde Biotin-PEG4-COOH is a PEG derivative composed of Biotin, 5 PEG units, and a carboxyl group (-COOH). Biotin can form a stable non-covalent bond with streptavidin. The carboxyl group can easily form a stable amide bond with the amino group, and can also form an ester bond with the hydroxyl group.

HY-W1048918D

mPEG40000-CM mPEG40000-COOH	Biochemical Assay Reagents
mPEG40000-CM (mPEG40000-COOH) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG40000-CM can be used for drug delivery .

HY-W1048918C

mPEG20000-CM mPEG20000-COOH	Biochemical Assay Reagents
mPEG20000-CM (mPEG20000-COOH) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG20000-CM can be used for drug delivery .

HY-W1048918E

mPEG3400-CM mPEG3400-COOH	Biochemical Assay Reagents
mPEG3400-CM (mPEG3400-COOH) has a reactive carboxyl group (-COOH) attached to the terminal site of the structure, which can form a stable amide bond with the amino group or an ester bond with the hydroxyl group. mPEG3400-CM can be used for drug delivery .

HY-W1123939B

Silane-PEG3400-COOH	Biochemical Assay Reagents
Silane-PEG3400-COOH can be used to modify proteins, peptides and other materials with active groups. The carboxyl group (-COOH) can easily form a stable amide bond with the amino group, and can also form an ester bond with the hydroxyl group. Silane-functionalized PEG (Silane-PEG-X) can be used to modify glass, silicon, etc .

HY-182833A

DPPE-PEG2000-NHS	Biochemical Assay Reagents
DPPE-PEG2000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-183104D

DSG-PEG10000-NHS	Biochemical Assay Reagents
DSG-PEG10000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-183104

DSG-PEG1000-NHS	Biochemical Assay Reagents
DSG-PEG1000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-183016

DMPE-PEG1000-NHS	Biochemical Assay Reagents
DMPE-PEG1000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-183104B

DSG-PEG3400-NHS	Biochemical Assay Reagents
DSG-PEG3400-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-183104A

DSG-PEG2000-NHS	Biochemical Assay Reagents
DSG-PEG2000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-W1048526C

8-Arm PEG10000-NH2 HCL 8-Arm PEG10000-amine HCL salt	Biochemical Assay Reagents
8-Arm PEG10000-NH2 (8-Arm PEG10000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048525C

8-Arm PEG10000-NH2 8-Arm PEG10000-Amine	Biochemical Assay Reagents
8-Arm PEG10000-NH2 (8-Arm PEG10000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048526B

8-Arm PEG40000-NH2 HCL 8-Arm PEG40000-amine HCL salt	Biochemical Assay Reagents
8-Arm PEG40000-NH2 (8-Arm PEG40000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-183016C

DMPE-PEG5000-NHS	Biochemical Assay Reagents
DMPE-PEG5000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-183016B

DMPE-PEG3400-NHS	Biochemical Assay Reagents
DMPE-PEG3400-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-182833D

DPPE-PEG10000-NHS	Biochemical Assay Reagents
DPPE-PEG10000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-182833B

DPPE-PEG3400-NHS	Biochemical Assay Reagents
DPPE-PEG3400-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-182833

DPPE-PEG1000-NHS	Biochemical Assay Reagents
DPPE-PEG1000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-183104C

DSG-PEG5000-NHS	Biochemical Assay Reagents
DSG-PEG5000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-W1048525A

8-Arm PEG20000-NH2 8-Arm PEG20000-Amine	Biochemical Assay Reagents
8-Arm PEG20000-NH2 (8-Arm PEG20000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-182833C

DPPE-PEG5000-NHS	Biochemical Assay Reagents
DPPE-PEG5000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-183016A

DMPE-PEG2000-NHS	Biochemical Assay Reagents
DMPE-PEG2000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

HY-183016D

DMPE-PEG10000-NHS	Biochemical Assay Reagents
DMPE-PEG10000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.

Cat. No.	Product Name	Target	Research Area

HY-P1070A

Amylin, amide, human TFA DAP amide, human TFA	Amylin Receptor	Metabolic Disease
Amylin, amide, human TFA, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human TFA inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent .

HY-P1070

Amylin, amide, human DAP amide, human	Amylin Receptor	Metabolic Disease
Amylin, amide, human, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent .

HY-P1883A

Bacterial Sortase Substrate III, Abz/DNP TFA	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP TFA is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP TFA undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .

HY-P2193

TAT-amide	Peptides	Infection
TAT-amide is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells .

HY-W008559

L-Tyrosinamide	Endogenous Metabolite	Metabolic Disease
L-Tyrosinamide is a derivative of Tyrosine, is an amino acid amide .

HY-P1531

γ-1-Melanocyte Stimulating Hormone (MSH), amide	Melanocortin Receptor	Cardiovascular Disease Metabolic Disease Endocrinology
γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na ⁺) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

HY-P5481

DABCYL-LPETG-EDANS	Peptides	Others
DABCYL-LPETG-EDANS is a biological active peptide. (This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.)

HY-P1922

γ-2-MSH (41-58), amide	Melanocortin Receptor	Endocrinology
γ-2-MSH (41-58), amide is derived from γ-2-MSH. γ-2-MSH is a twelve amino acid peptide that is derived from the N-terminal fragment of proopiomelanocortin (POMC) and contains the His-Phe-Arg-Trp motif common to all melanocortin endogenous agonist ligands .

HY-P4332

Boc-Glu(OBzl)-Ala-Arg-AMC	Fluorescent Dye Ser/Thr Protease	Cardiovascular Disease
Boc-Glu(OBzl)-Ala-Arg-AMC is a fluorogenic substrate for coagulation factor XIa and trypsin. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .

HY-P1883

Bacterial Sortase Substrate III, Abz/DNP	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .

HY-P4333

Boc-Glu(OBzl)-Gly-Arg-AMC	Fluorescent Dye	Cardiovascular Disease
Boc-Glu(OBzl)-Gly-Arg-AMC is a fluorogenic substrate for factors IXa and XIIa. The cleavage of the amide bond between arginine and the methylcoumarin amide group releases fluorescent 7-Amino-4-methylcoumarin (HY-D0027) .

HY-P2193A

TAT-amide TFA	Peptides	Infection
TAT-amide TFA is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells .

HY-P5483

Retro-indolicidin	Bacterial	Others
Retro-indolicidin is a biological active peptide. (Reverse peptide of indolicidin (Rev4) is a 13-amino acid residue peptide based on the sequence of indolicidin. Indolicidin, a member of the cathelicidin protein family, is a 13-amino acid residue cationic, antimicrobial peptide-amide isolated from the cytoplasmic granules of bovine neutrophils. The synthetic peptide Rev4 has been shown to possess strong antimicrobial as well as protease inhibitory activities in vitro.)

HY-P7060

NT 13 TPPT	iGluR	Neurological Disease
NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.

HY-P3284

Mastoparan M tetraacetate	Peptides	Cancer
Mastoparan M tetraacetate is a tetrapeptide amide isolated from the Chinese giant hornet (Vespa mandarinia). The amino acid sequence of Mastoparan M tetraacetate shares some structural homology with Mastoparan X, a wasp venom isolated from the Chinese giant hornet as well .

HY-P1169A

Ac-IETD-AFC TFA	Caspase	Others
Ac-IETD-AFC TFA is a synthetic fluorogenic substrate that can be used to specifically detect caspase-8 activity. INDO 1 pentasodium is imbued with the fluorophore AFC (7-amino-4-trifluoromethylcoumarin). When caspase-8 recognizes and cleaves the amide bond following the IETD sequence in this substrate, AFC is released and emits fluorescence (Ex = ~400 nm; Em = ~505 nm) .

HY-P5484

SMAP-18	Bacterial	Others
SMAP-18 is a biological active peptide. (SMAP-18 is a 18-amino acid residue peptide amide which is a truncated form of SMAP-29. Sheep myeloid antimicrobial peptide-29 (SMAP-29) displays extremely high antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. SMAP-18 displays much higher cell selectivity as compared to parental SMAP-29 because of its decreased hemolytic activity and retained antimicrobial activity.)

HY-P5514

NF(N-Me)GA(N-Me)IL Amylin (22-27) [NMeG24, NMeI26], human (IAPP)	Peptides	Others
NF(N-Me)GA(N-Me)IL is a biological active peptide. (This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.)

HY-P11605

Big endothelin-3 (Human, 1-41 amide)	Drug Intermediate Endothelin Receptor	Cardiovascular Disease Neurological Disease
Big endothelin-3 (Human, 1-41 amide) is a precursor molecule of the Endothelin-3 (ET-3) peptide composing of 41 amino acids .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0390

L-Glutamine 25+ Cited Publications L-Glutamic acid 5-amide	Structural Classification Classification of Application Fields Anti-aging Endocrine diseases Metabolic Disease Amino acids Endogenous metabolite Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder Cancer Source Classification	Environmental Pollutants Endogenous Metabolite mGluR Ferroptosis
L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells .

HY-15121

L-Theanine 5 Publications Verification L-Glutamic acid γ-ethyl amide; Nγ-Ethyl-L-glutamine	Microorganisms Neurological Disease Classification of Application Fields Anti-aging Amino acids Camellia sinensis (L.) O. Ktze. Plants Disease Research Fields Source Classification Theaceae	Apoptosis Endogenous Metabolite Reactive Oxygen Species (ROS)
L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through the blood–brain barrier and is orally active .

HY-15121R

L-Theanine (Standard) L-Glutamic acid γ-ethyl amide (Standard); Nγ-Ethyl-L-glutamine (Standard)	Structural Classification Microorganisms Amino acids Camellia sinensis (L.) O. Ktze. Plants Source Classification Theaceae	Reference Standards Apoptosis Endogenous Metabolite Reactive Oxygen Species (ROS)
L-Theanine (Standard) is the analytical standard of L-Theanine. This product is intended for research and analytical applications. L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through the blood–brain barrier and is orally active .

HY-100801R

L-threo-3-Hydroxyaspartic acid (Standard)	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	EAAT Reference Standards
Prilocaine (hydrochloride) (Standard) is the analytical standard of Prilocaine (hydrochloride). This product is intended for research and analytical applications. Prilocaine hydrochloride, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects .

Cat. No.	Product Name	Chemical Structure

HY-15121S

L-Theanine-d5

L-Theanine-d₅ is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide）is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake .

HY-15121S1

L-Theanine-13C2,15N2

L-Theanine- ¹³C₂, ¹⁵N₂ (L-Glutamic Acid γ-ethyl amide- ¹³C₂, ¹⁵N₂) is the ¹³C- and ¹⁵N-labeled L-Theanine (HY-15121). L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through the blood–brain barrier and is orally active.

HY-N0390S10

L-Glutamine-1,2-13C2
L-Glutamine-1,2- ¹³C₂ is the ¹³C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells .

HY-N0390S15

L-Glutamine-d4
L-Glutamine-d₄ (L-Glutamic acid 5-amide-d₄) is the deuterium labeled L-Glutamine (HY-N0390). L-Glutamine is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells .

HY-W017443S1

L-Asparagine-amide-15N monohydrate

L-Asparagine-amide- ¹⁵N monohydrate is the ¹⁵N-labeled L-Asparagine monohydrate (HY-W017443). L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia .

HY-B0137AS

Prilocaine-d7 hydrochloride
Prilocaine-d₇ (hydrochloride) is deuterium labeled Prilocaine (hydrochloride). Prilocaine hydrochloride, an amino amide, is a Na, K-ATPase inhibitor. Prilocaine has neurotoxic effects .

HY-N0390S11

L-Glutamine-2-13C
L-Glutamine-2- ¹³C is the ¹³C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells .

HY-W704786

Prilocaine Hydrochloride-d7
Prilocaine Hydrochloride-d₇ is the deuterium labeled Prilocaine hydrochloride (HY-B0137A). Prilocaine hydrochloride, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects .

HY-W766574

L-Glutamine-5-13C Hydrochloride
L-Glutamine-5- ¹³C Hydrochloride is the ¹³C-labeled L-Glutamine (HY-N0390). L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells .

Cat. No.	Product Name		Classification

HY-157745

m-PEG40000-NHS ester mPEG40000-SC; mPEG40000-Succinimidyl ester		Polymers
m-PEG-NHS ester (mPEG-SC; mPEG-Succinimidyl ester) (MW 40000) is a polyethylene glycol derivative. m-PEG-NHS ester serves as a modifying agent that reacts with free amino groups on the surface of protein or polypeptide molecules to form stable amide bonds, thereby covalently linking PEG chains to biomacromolecules, improving their antigenicity and immunogenicity, and facilitating the preparation of injectable formulations .

HY-169794

N-Palmitoyl-phenylalanine		Cationic Lipids
N-Palmitoyl-phenylalanine is an N-acyl amide that contains the long-chain saturated fatty acid Palmitic acid (HY-N0830) conjugated via an amide bond to the essential amino acid L-Phenylalanine (HY-N0215). N-Palmitoyl-phenylalanine inhibits pre-mRNA splicing in HeLa cell nuclear lysates (IC₅₀ ＞ 400 μM) but has no splicing activity in intact HeLa cells .

HY-172270D

DSPE-PEG5000-Mal-Cys-KTLLPTP		Pegylated Lipids
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

HY-172270

DSPE-PEG1000-Mal-Cys-KTLLPTP		Pegylated Lipids
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

HY-172270A

DSPE-PEG2000-Mal-Cys-KTLLPTP		Pegylated Lipids
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

HY-172270C

DSPE-PEG3400-Mal-Cys-KTLLPTP		Pegylated Lipids
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .

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