(R)-2-Amino-3-phenylpropanamide
Based on 1 Customer Validation
(R)-2-Amino-3-phenylpropanamide (D-Phenylalanine amide) is a non-natural D-α-amino acid derivative and chiral amino acid amide. (R)-2-Amino-3-phenylpropanamide can be converted into D-Phenylalanine (HY-Y0079), which is applicable to the construction of all-D antimicrobial peptides and the synthesis of anti-HIV reagents. (R)-2-Amino-3-phenylpropanamide serves as a reagent for synthesizing benzoxaborole derivative 6, a dual covalent binder of Pseudomonas aeruginosa PBP3. (R)-2-Amino-3-phenylpropanamide is used in colon cancer-related research.
For research use only. We do not sell to patients.
- Purity : 99.23%
- CAS No.: 5241-59-8
- Formula: C9H12N2O
- Molecular Weight:164.21
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 5241-59-8
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Appearance Solid
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Molecular Weight 164.21
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Formula C9H12N2O
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Color White to off-white
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SMILES
C([C@H](C(N)=O)N)C1=CC=CC=C1
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Synonyms
D-Phenylalanine amide; H-D-Phe-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Morán-Ramallal R, et al. Enantiopure trans-3-arylaziridine-2-carboxamides: preparation by bacterial hydrolysis and ring-openings toward enantiopure, unnatural D-α-amino acids. J Org Chem. 2010;75(19):6614-6624. [Content Brief]
[2]. Newman H, et al. High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes. J Med Chem. 2021;64(15):11379-11394. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R)-2-Amino-3-phenylpropanamide Related Classifications
HY-W097355 Related Classifications
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Keywords
- (R)-2-Amino-3-phenylpropanamide
- 5241-59-8
- D-Phenylalanine amide
- H-D-Phe-NH2
- Amino Acid Derivatives
- Drug Intermediate
- chiral amino acid amide
- anti-HIV agents
- D-α-amino acid derivative
- depsipeptide residue substitution
- Pseudomonas aeruginosa
- D-phenylalanine
- benzoxaborole derivative
- colon cancer
- all-D antimicrobial peptides
- PBP3
- Inhibitor
- inhibitor
- inhibit