NH2-PEG5000-NH2
Based on 1 Customer Validation
NH2-PEG5000-NH2 is a PEG (MW = 5000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups.
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- Pureté : 98.0%
- CAS No.: 956496-54-1
- Masse moléculaire:5000 (average)
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Stockage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
NH2-PEG-NH2 can be used for amine functionalization of magnetic nanoparticles (MNPs) and subsequent fluorescent/targeted ligand coupling, but the double-terminated amino groups easily lead to nanoparticle bridging and aggregation, shortening blood circulation time[1].
NH2-PEG-NH2 is a key bifunctional linker for preparing folic acid-PEG-lipid derivatives. Its flexible PEG chain can reduce steric hindrance and maintain the binding ability of folic acid to folic acid receptors[2].
NH2-PEG800-NH2 can improve the surface bioactivity of bioinert 3D carbon fiber/carbon composites (3D C/C), enabling it to induce apatite deposition in simulated body fluid (SBF)[3].
NH2-PEG5000-NH2 is an effective surface stabilizer for obtaining low-toxicity, cell-labelable zinc oxide quantum dots (ZnO QDs)[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 956496-54-1
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Appearance Solid
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Masse moléculaire 5000 (average)
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Color White to off-white
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SMILES
NCCOCCN.[n]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Pureté et documentation
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Fiche technique (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Hsu SH, et al. Synthesis of water-dispersible zinc oxide quantum dots with antibacterial activity and low cytotoxicity for cell labeling. Nanotechnology. 2013 Nov 29;24(47):475102. [Content Brief]
[2]. Yan Y, Qi XR. [Preparation and properties of folate receptor-targeted cationic liposomes]. Yao Xue Xue Bao. 2008 Nov;43(11):1134-9. Chinese. [Content Brief]
[3]. Li S, et al. Collagen/apatite coating on 3-dimensional carbon/carbon composite. J Biomed Mater Res. 1998 Jun 15;40(4):520-9. [Content Brief]
[4]. Arami H, et al. In vivo multimodal magnetic particle imaging (MPI) with tailored magneto/optical contrast agents. Biomaterials. 2015 Jun;52:251-61. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NH2-PEG5000-NH2 Related Classifications
HY-W451406A Related Classifications
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