NH2-PEG400-NH2
Based on 1 Customer Validation
NH2-PEG400-NH2 is a PEG (MW = 400) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups.
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- CAS No.: 956496-54-1
- 화학식: C4H12N2O2
- 분자량:400 (average)
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보관:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
NH2-PEG-NH2 can be used for amine functionalization of magnetic nanoparticles (MNPs) and subsequent fluorescent/targeted ligand coupling, but the double-terminated amino groups easily lead to nanoparticle bridging and aggregation, shortening blood circulation time[1].
NH2-PEG-NH2 is a key bifunctional linker for preparing folic acid-PEG-lipid derivatives. Its flexible PEG chain can reduce steric hindrance and maintain the binding ability of folic acid to folic acid receptors[2].
NH2-PEG800-NH2 can improve the surface bioactivity of bioinert 3D carbon fiber/carbon composites (3D C/C), enabling it to induce apatite deposition in simulated body fluid (SBF)[3].
NH2-PEG5000-NH2 is an effective surface stabilizer for obtaining low-toxicity, cell-labelable zinc oxide quantum dots (ZnO QDs)[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 956496-54-1
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Appearance Liquid
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분자량 400 (average)
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화학식 C4H12N2O2
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SMILES
NOCCOCCN.[n]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
순도&문서
References
[1]. Hsu SH, et al. Synthesis of water-dispersible zinc oxide quantum dots with antibacterial activity and low cytotoxicity for cell labeling. Nanotechnology. 2013 Nov 29;24(47):475102. [Content Brief]
[2]. Yan Y, Qi XR. [Preparation and properties of folate receptor-targeted cationic liposomes]. Yao Xue Xue Bao. 2008 Nov;43(11):1134-9. Chinese. [Content Brief]
[3]. Li S, et al. Collagen/apatite coating on 3-dimensional carbon/carbon composite. J Biomed Mater Res. 1998 Jun 15;40(4):520-9. [Content Brief]
[4]. Arami H, et al. In vivo multimodal magnetic particle imaging (MPI) with tailored magneto/optical contrast agents. Biomaterials. 2015 Jun;52:251-61. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)