NH2-PEG2000-NH2
Based on 1 Customer Validation
NH2-PEG2000-NH2 is a PEG (MW = 2000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups.
For research use only. We do not sell to patients.
- CAS No.: 956496-54-1
- Molecular Weight:2000 (average)
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
NH2-PEG-NH2 can be used for amine functionalization of magnetic nanoparticles (MNPs) and subsequent fluorescent/targeted ligand coupling, but the double-terminated amino groups easily lead to nanoparticle bridging and aggregation, shortening blood circulation time[1].
NH2-PEG-NH2 is a key bifunctional linker for preparing folic acid-PEG-lipid derivatives. Its flexible PEG chain can reduce steric hindrance and maintain the binding ability of folic acid to folic acid receptors[2].
NH2-PEG800-NH2 can improve the surface bioactivity of bioinert 3D carbon fiber/carbon composites (3D C/C), enabling it to induce apatite deposition in simulated body fluid (SBF)[3].
NH2-PEG5000-NH2 is an effective surface stabilizer for obtaining low-toxicity, cell-labelable zinc oxide quantum dots (ZnO QDs)[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 956496-54-1
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Appearance Solid
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Molecular Weight 2000 (average)
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Color White to off-white
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SMILES
NCCOCCN.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Hsu SH, et al. Synthesis of water-dispersible zinc oxide quantum dots with antibacterial activity and low cytotoxicity for cell labeling. Nanotechnology. 2013 Nov 29;24(47):475102. [Content Brief]
[2]. Yan Y, Qi XR. [Preparation and properties of folate receptor-targeted cationic liposomes]. Yao Xue Xue Bao. 2008 Nov;43(11):1134-9. Chinese. [Content Brief]
[3]. Li S, et al. Collagen/apatite coating on 3-dimensional carbon/carbon composite. J Biomed Mater Res. 1998 Jun 15;40(4):520-9. [Content Brief]
[4]. Arami H, et al. In vivo multimodal magnetic particle imaging (MPI) with tailored magneto/optical contrast agents. Biomaterials. 2015 Jun;52:251-61. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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