NH2-PEG10000-NH2 

NH2-PEG10000-NH2 is a PEG (MW = 10000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups^[1][2][3][4].

NH2-PEG-NH2 can be used for amine functionalization of magnetic nanoparticles (MNPs) and subsequent fluorescent/targeted ligand coupling, but the double-terminated amino groups easily lead to nanoparticle bridging and aggregation, shortening blood circulation time^[1].
NH2-PEG-NH2 is a key bifunctional linker for preparing folic acid-PEG-lipid derivatives. Its flexible PEG chain can reduce steric hindrance and maintain the binding ability of folic acid to folic acid receptors^[2].
NH2-PEG800-NH2 can improve the surface bioactivity of bioinert 3D carbon fiber/carbon composites (3D C/C), enabling it to induce apatite deposition in simulated body fluid (SBF)^[3].
NH2-PEG5000-NH2 is an effective surface stabilizer for obtaining low-toxicity, cell-labelable zinc oxide quantum dots (ZnO QDs)^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

10000 (average)

(C₂H₄O)nC₂H₈N₂O

NOCCOCCN.[n]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Hsu SH, et al. Synthesis of water-dispersible zinc oxide quantum dots with antibacterial activity and low cytotoxicity for cell labeling. Nanotechnology. 2013 Nov 29;24(47):475102.  [Content Brief]

  [2]. Yan Y, Qi XR. [Preparation and properties of folate receptor-targeted cationic liposomes]. Yao Xue Xue Bao. 2008 Nov;43(11):1134-9. Chinese.  [Content Brief]

  [3]. Li S, et al. Collagen/apatite coating on 3-dimensional carbon/carbon composite. J Biomed Mater Res. 1998 Jun 15;40(4):520-9.  [Content Brief]

  [4]. Arami H, et al. In vivo multimodal magnetic particle imaging (MPI) with tailored magneto/optical contrast agents. Biomaterials. 2015 Jun;52:251-61.  [Content Brief]