9-(Boc-amino)nonanoic acid
Based on 1 Customer Validation
9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. 9-(Boc-amino)nonanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
For research use only. We do not sell to patients.
- Purity : 99.89%
- CAS No.: 173435-78-4
- Formula: C14H27NO4
- Molecular Weight:273.37
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
All PROTAC Linkers Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 173435-78-4
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Appearance Solid
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Molecular Weight 273.37
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Formula C14H27NO4
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Color White to off-white
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SMILES
O=C(O)CCCCCCCCNC(OC(C)(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (365.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (238 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6580 mL | 18.2902 mL | 36.5805 mL | 91.4511 mL |
| 5 mM | 0.7316 mL | 3.6580 mL | 7.3161 mL | 18.2902 mL | |
| 10 mM | 0.3658 mL | 1.8290 mL | 3.6580 mL | 9.1451 mL | |
| 15 mM | 0.2439 mL | 1.2193 mL | 2.4387 mL | 6.0967 mL | |
| 20 mM | 0.1829 mL | 0.9145 mL | 1.8290 mL | 4.5726 mL | |
| 25 mM | 0.1463 mL | 0.7316 mL | 1.4632 mL | 3.6580 mL | |
| 30 mM | 0.1219 mL | 0.6097 mL | 1.2193 mL | 3.0484 mL | |
| 40 mM | 0.0915 mL | 0.4573 mL | 0.9145 mL | 2.2863 mL | |
| 50 mM | 0.0732 mL | 0.3658 mL | 0.7316 mL | 1.8290 mL | |
| 60 mM | 0.0610 mL | 0.3048 mL | 0.6097 mL | 1.5242 mL | |
| 80 mM | 0.0457 mL | 0.2286 mL | 0.4573 mL | 1.1431 mL | |
| 100 mM | 0.0366 mL | 0.1829 mL | 0.3658 mL | 0.9145 mL |