Prilocaine acetate
Based on 1 publication(s) in Google Scholar
Prilocaine acetate, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine acetate has neurotoxic effects.
For research use only. We do not sell to patients.
- Formula: C15H24N2O3
- Molecular Weight:280.36
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Prilocaine acetate
More
Biological Activity
Na/K-ATPase[2]
Prilocaine acetate is more potent in inhibiting the Na,K-ATPase of plasma membranes of LM cells (transformed fibroblasts) at 37 °C (43.8 mM) than at 25 °C (28.2 mM)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 280.36
-
Formula C15H24N2O3
-
SMILES
CC(NCCC)C(NC1=CC=CC=C1C)=O.CC(O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Stem Cell Res Ther
Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation. [Abstract]2021 Feb 4;12(1):107. PMID: 33541421
Purity & Documentation
References
[1]. M Mete, et al. Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2a cell line. Biotech Histochem. 2015 Apr;90(3):216-22. [Content Brief]
[2]. H Kutchai, et al. Effects of local anaesthetics on the activity of the Na,K-ATPase of canine renal medulla. Pharmacol Res. 2000 Jan;41(1):1-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)