N-(Amino-PEG5)-N-bis(PEG4-acid)
Based on 1 Customer Validation
N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG derivative containing an amino group with two terminal carboxylic acids. The amino group is reactive with carboxylic acids, activated NHS esters. The terminal carboxylic acids can react with primary amine groups in the presence of activators to form a stable amide bond. N-(Amino-PEG5)-N-bis(PEG4-acid) can be useful in the development of antibody drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 99.52%
- CAS No.: 2093152-86-2
- Formula: C34H68N2O17
- Molecular Weight:776.91
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2093152-86-2
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Appearance Liquid (Density: 1.154±0.06 g/cm3)
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Molecular Weight 776.91
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Formula C34H68N2O17
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Color Colorless to light yellow
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SMILES
O=C(O)CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCOCCN)CCOCCOCCOCCOCCC(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 175 mg/mL (225.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2872 mL | 6.4358 mL | 12.8715 mL | 32.1788 mL |
| 5 mM | 0.2574 mL | 1.2872 mL | 2.5743 mL | 6.4358 mL | |
| 10 mM | 0.1287 mL | 0.6436 mL | 1.2872 mL | 3.2179 mL | |
| 15 mM | 0.0858 mL | 0.4291 mL | 0.8581 mL | 2.1453 mL | |
| 20 mM | 0.0644 mL | 0.3218 mL | 0.6436 mL | 1.6089 mL | |
| 25 mM | 0.0515 mL | 0.2574 mL | 0.5149 mL | 1.2872 mL | |
| 30 mM | 0.0429 mL | 0.2145 mL | 0.4291 mL | 1.0726 mL | |
| 40 mM | 0.0322 mL | 0.1609 mL | 0.3218 mL | 0.8045 mL | |
| 50 mM | 0.0257 mL | 0.1287 mL | 0.2574 mL | 0.6436 mL | |
| 60 mM | 0.0215 mL | 0.1073 mL | 0.2145 mL | 0.5363 mL | |
| 80 mM | 0.0161 mL | 0.0804 mL | 0.1609 mL | 0.4022 mL | |
| 100 mM | 0.0129 mL | 0.0644 mL | 0.1287 mL | 0.3218 mL |
N-(Amino-PEG5)-N-bis(PEG4-acid) Related Classifications
HY-130695 Related Classifications
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