1. Membrane Transporter/Ion Channel Neuronal Signaling
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  3. NT 13

NT 13  (Synonyms: TPPT)

Cat. No.: HY-P7060
Handling Instructions

NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

NT 13 Chemical Structure

NT 13 Chemical Structure

CAS No. : 117928-93-5

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Description

NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.

IC50 & Target

Target: NMDAR[1]

In Vitro

NT 13 derivatives are used in the study of depression, anxiety, and other related diseases. Some NT 13 derivatives are NMDAR partial agonist[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

414.45

Formula

C18H30N4O7

CAS No.
Sequence

Thr-Pro-Pro-Thr

Sequence Shortening

TPPT

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : ≥ 122.5 mg/mL (295.57 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4128 mL 12.0642 mL 24.1284 mL
5 mM 0.4826 mL 2.4128 mL 4.8257 mL
10 mM 0.2413 mL 1.2064 mL 2.4128 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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NT 13
Cat. No.:
HY-P7060
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