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  3. NT 13

NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

NT 13 Chemical Structure

NT 13 Chemical Structure

CAS No. : 117928-93-5

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Description

NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.

IC50 & Target

Target: NMDAR[1]

In Vitro

NT 13 derivatives are used in the study of depression, anxiety, and other related diseases. Some NT 13 derivatives are NMDAR partial agonist[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

414.45

Formula

C18H30N4O7

CAS No.
Sequence

Thr-Pro-Pro-Thr

Sequence Shortening

TPPT

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : ≥ 122.5 mg/mL (295.57 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4128 mL 12.0642 mL 24.1284 mL
5 mM 0.4826 mL 2.4128 mL 4.8257 mL
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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4128 mL 12.0642 mL 24.1284 mL 60.3209 mL
5 mM 0.4826 mL 2.4128 mL 4.8257 mL 12.0642 mL
10 mM 0.2413 mL 1.2064 mL 2.4128 mL 6.0321 mL
15 mM 0.1609 mL 0.8043 mL 1.6086 mL 4.0214 mL
20 mM 0.1206 mL 0.6032 mL 1.2064 mL 3.0160 mL
25 mM 0.0965 mL 0.4826 mL 0.9651 mL 2.4128 mL
30 mM 0.0804 mL 0.4021 mL 0.8043 mL 2.0107 mL
40 mM 0.0603 mL 0.3016 mL 0.6032 mL 1.5080 mL
50 mM 0.0483 mL 0.2413 mL 0.4826 mL 1.2064 mL
60 mM 0.0402 mL 0.2011 mL 0.4021 mL 1.0053 mL
80 mM 0.0302 mL 0.1508 mL 0.3016 mL 0.7540 mL
100 mM 0.0241 mL 0.1206 mL 0.2413 mL 0.6032 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NT 13
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HY-P7060
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