Ac-IETD-AFC TFA
Based on 1 publication(s) in Google Scholar
Ac-IETD-AFC TFA is a synthetic fluorogenic substrate that can be used to specifically detect caspase-8 activity. INDO 1 pentasodium is imbued with the fluorophore AFC (7-amino-4-trifluoromethylcoumarin). When caspase-8 recognizes and cleaves the amide bond following the IETD sequence in this substrate, AFC is released and emits fluorescence (Ex = ~400 nm; Em = ~505 nm).
For research use only. We do not sell to patients.
- Formula: C33H39F6N5O14
- Molecular Weight:843.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Ac-IETD-AFC TFA
MoreAll Caspase Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 843.68
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Formula C33H39F6N5O14
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Sequence
Ac-Ile-Glu-Thr-Asp-{AFC}
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Sequence Shortening
Ac-IETD-{AFC}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Genes (Basel)
Characterization of the Apoptotic and Antimicrobial Activities of Two Initiator Caspases of Sea Cucumber Apostichopus japonicus. [Abstract]2024 Apr 25;15(5):540. PMID: 38790170
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ac-IETD-AFC TFA Related Classifications
HY-P1169A Related Classifications
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