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deuterium-labeled derivatives

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (24) 11β-HSD (2) ADC Payload (3) Adrenergic Receptor (8) AMPK (1) Amyloid-β (2) Androgen Receptor (1) Antibiotic (7) Apoptosis (21) Autophagy (11) Bacterial (17) Bcl-2 Family (4) Biochemical Assay Reagents (8) Calcium Channel (2) Carbonic Anhydrase (1) Casein Kinase (1) Caspase (3) CETP (1) CHIKV (3) Chloride Channel (1) Cholinesterase (ChE) (1) COX (4) Cytochrome P450 (2) Dipeptidyl Peptidase (1) DNA Alkylator/Crosslinker (1) DNA/RNA Synthesis (5) DOCK (1) Dopamine Receptor (4) Drug Derivative (6) Drug Intermediate (9) Drug Isomer (1) Drug Metabolite (2) Drug-Linker Conjugates for ADC (4) Endogenous Metabolite (51) ERK (6) Estrogen Receptor/ERR (2) FKBP (1) Fluorescent Dye (3) Fungal (5) FXR (3) G protein-coupled Bile Acid Receptor 1 (3) GABA Receptor (4) Glucocorticoid Receptor (1) Glycosidase (1) HCV (1) Hedgehog (1) Herbicide (1) Histamine Receptor (4) HIV (2) HSV (2) IFNAR (1) iGluR (2) IKK (1) Influenza Virus (4) Insecticide (1) Interleukin Related (3) Isotope-Labeled Compounds (198) Keap1-Nrf2 (6) Ligands for E3 Ligase (2) LPL Receptor (3) mAChR (5) MDM-2/p53 (3) MEK (5) Microtubule/Tubulin (4) Molecular Glues (2) mTOR (2) Necroptosis (2) NF-κB (8) NO Synthase (2) Nucleoside Antimetabolite/Analog (1) P-glycoprotein (3) Parasite (10) PGE synthase (1) Phosphodiesterase (PDE) (3) PKC (1) Potassium Channel (1) Progesterone Receptor (3) Prostaglandin Receptor (1) RAR/RXR (2) Reactive Oxygen Species (ROS) (1) SARS-CoV (3) Sirtuin (1) SOD (2) Sodium Channel (8) Syk (1) TNF Receptor (1) Topoisomerase (2) TRP Channel (1) Vasopressin Receptor (1) VD/VDR (1) VSV (1)
By Research Areas:	Cancer (61) Cardiovascular Disease (17) Endocrinology (6) Infection (29) Inflammation/Immunology (33) Metabolic Disease (27) Neurological Disease (37)

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Amino Acid Derivatives (24)

11β-HSD (2)

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AMPK (1)

Amyloid-β (2)

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Apoptosis (21)

Autophagy (11)

Bacterial (17)

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CETP (1)

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COX (4)

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Drug-Linker Conjugates for ADC (4)

Endogenous Metabolite (51)

ERK (6)

Estrogen Receptor/ERR (2)

FKBP (1)

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G protein-coupled Bile Acid Receptor 1 (3)

GABA Receptor (4)

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Glycosidase (1)

HCV (1)

Hedgehog (1)

Herbicide (1)

Histamine Receptor (4)

HIV (2)

HSV (2)

IFNAR (1)

iGluR (2)

IKK (1)

Influenza Virus (4)

Insecticide (1)

Interleukin Related (3)

Isotope-Labeled Compounds (198)

Keap1-Nrf2 (6)

Ligands for E3 Ligase (2)

LPL Receptor (3)

mAChR (5)

MDM-2/p53 (3)

MEK (5)

Microtubule/Tubulin (4)

Molecular Glues (2)

mTOR (2)

Necroptosis (2)

NF-κB (8)

NO Synthase (2)

Nucleoside Antimetabolite/Analog (1)

P-glycoprotein (3)

Parasite (10)

PGE synthase (1)

Phosphodiesterase (PDE) (3)

PKC (1)

Potassium Channel (1)

Progesterone Receptor (3)

Prostaglandin Receptor (1)

RAR/RXR (2)

Reactive Oxygen Species (ROS) (1)

SARS-CoV (3)

Sirtuin (1)

SOD (2)

Sodium Channel (8)

Syk (1)

TNF Receptor (1)

Topoisomerase (2)

TRP Channel (1)

Vasopressin Receptor (1)

VD/VDR (1)

VSV (1)

By Research Areas:

Cancer (61)

Cardiovascular Disease (17)

Endocrinology (6)

Infection (29)

Inflammation/Immunology (33)

Metabolic Disease (27)

Neurological Disease (37)

234

Inhibitors & Agonists

Peptides

232

Isotope-Labeled Compounds

Targets Recommended: Amino Acid Derivatives

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010388S1

Creatine-d3 2 Publications Verification	Endogenous Metabolite	Metabolic Disease
Creatine-d₃ is the deuterium labeled Creatine (HY-W010388) . Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain .

HY-15459S

Cabazitaxel-d6 XRP6258-d₆; RPR-116258A-d₆; taxoid XRP6258-d₆	Microtubule/Tubulin Autophagy	Cancer
Cabazitaxel-d₆ is the deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity .

HY-15459S1

Cabazitaxel-d9 XRP6258-d₉; RPR-116258A-d₉; taxoid XRP6258-d₉	Isotope-Labeled Compounds Microtubule/Tubulin Autophagy	Cancer
Cabazitaxel-d₉ is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-122464S2

(±)-Jasmonic acid-d5	Isotope-Labeled Compounds	Others
(±)-Jasmonic acid-d₅ is the deuterium labeled (±)-Jasmonic acid. (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.

HY-W013940S1

DL-Cystine-d6	Isotope-Labeled Compounds	Others
DL-Cystine-d₆ is the deuterium labeled DL-Cystine (HY-W013940). DL-Cystine is a cysteine derivative .

HY-N0091S5

Hypoxanthine-d4	Isotope-Labeled Compounds Endogenous Metabolite	Others
Hypoxanthine-d₄ is the deuterium labeled Hypoxanthine . Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia .

HY-W017462S

Creatine-d5 monohydrate	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Creatine-d₅ (monohydrate) is the deuterium labeled Creatine monohydrate. Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain .

HY-13666S

Levamisole-d5 hydrochloride (-)-Tetramisole-d₅ hydrochloride	Isotope-Labeled Compounds Parasite HSV	Infection Neurological Disease
Levamisole-d₅ (hydrochloride) is the deuterium labeled Levamisole hydrochloride. Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV .

HY-N0682S1

Pyridoxine-d2 hydrochloride Pyridoxol-d2 hydrochloride; Vitamin B6-d2 hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite Keap1-Nrf2	Neurological Disease
Pyridoxine-d₂ (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

HY-N7113S

Squalane-d62	Isotope-Labeled Compounds	Cancer
Squalane-d₆₂ is the deuterium labeled Squalane . Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities .

HY-13566AS

Belotecan-d7 hydrochloride	Topoisomerase	Cancer
Belotecan-d₇ (hydrochloride) is the deuterium labeled Belotecan hydrochloride. Belotecan hydrochloride (CKD-602 hydrochloride), a Topoisomerase I inhibitor, is a synthetic camptothecin derivative .

HY-113411S

3-Hydroxyglutaric acid-d5	Endogenous Metabolite	Others
3-Hydroxyglutaric acid-d₅ is the deuterium labeled 3-Hydroxyglutaric acid. 3-Hydroxyglutaric acid is a glutaric acid derivative .

HY-N0091S6

Hypoxanthine-d2 1 Publications Verification	Endogenous Metabolite	Others
Hypoxanthine-d₂ is the deuterium labeled Hypoxanthine . Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia .

HY-N1914S1

Ergothioneine-d9 1 Publications Verification L-(+)-Ergothioneine-d₉	Endogenous Metabolite	Others
Ergothioneine-d₉ is the deuterium labeled Ergothioneine. Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant .

HY-Y0264S1

4-Hydroxybenzoic acid-d4	Endogenous Metabolite Bacterial	Infection
4-Hydroxybenzoic acid-d₄ is the deuterium labeled 4-Hydroxybenzoic acid. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.

HY-I0960S4

Uracil-d2	Endogenous Metabolite	Cancer
Uracil-d₂ is the deuterium labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-10882S

Clotrimazole-d5	Isotope-Labeled Compounds Fungal Bacterial Autophagy Antibiotic	Infection Cancer
Clotrimazole-d₅ is the deuterium labeled Clotrimazole. Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity .

HY-W017163S1

7-Methylxanthine-d3	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
7-Methylxanthine-d₃ is deuterium labeled 7-Methylxanthine. 7-Methylxanthine, a methyl derivative of xanthine, is one of the purine components in urinary calculi .

HY-W013940S

DL-Cystine-d4	Isotope-Labeled Compounds	Others
DL-Cystine-d₄ is the deuterium labeled DL-Cystine (HY-W013940). DL-Cystine is a cysteine derivative .

HY-I0960S9

Uracil-d4	Endogenous Metabolite	Cancer
Uracil-d₄ is the deuterium labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].

HY-122464S1

Jasmonic acid-d5	Isotope-Labeled Compounds	Others
Jasmonic acid-d₅ is deuterium labeled (±)-Jasmonic acid. (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.

HY-17393S

Carboplatin-d4 NSC 241240-d₄	Isotope-Labeled Compounds DNA Alkylator/Crosslinker Autophagy DNA/RNA Synthesis	Cancer
Carboplatin-d₄ is the deuterium labeled Carboplatin. Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.

HY-W738417

Phthalaldehyde-d6	Isotope-Labeled Compounds Biochemical Assay Reagents	Others
Phthalaldehyde-d₆ is the deuterium labeled Phthalaldehyde (HY-W012669). Phthalaldehyde is a biochemical assay reagent, which modifies the amino acid and measure the derivative through HPLC. Phthalaldehyde forms a fluorescent compound with α-amino group .

HY-135170S

Myristoyl-L-carnitine-d3 chloride	Isotope-Labeled Compounds	Others
Myristoyl-L-carnitine-d₃ chloride is the deuterium labeled Myristoyl-L-carnitine chloride (HY-135170). Myristoyl-L-Carnitine Chloride is a natural long-chain glycoline, amino acid derivative .

HY-I0960S6

Uracil-d2-1	Endogenous Metabolite	Cancer
Uracil-d₂-1 is the deuterium labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-B0863S

Glyphosate-d2	Isotope-Labeled Compounds Apoptosis Autophagy Necroptosis	Neurological Disease
Glyphosate-d₂ is the deuterium labeled Glyphosate. Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants .

HY-W011713S

N-(4-Aminobenzoyl)-L-glutamic acid-d4	Isotope-Labeled Compounds	Others
N-(4-Aminobenzoyl)-L-glutamic acid-d₄ is the deuterium labeled N-(4-Aminobenzoyl)-L-glutamic acid (HY-W011713) . (4-Aminobenzoyl)-L-glutamic acid is a glutamic acid derivative .

HY-113331S1

Thromboxane B2-d9	Isotope-Labeled Compounds Prostaglandin Receptor	Inflammation/Immunology
Thromboxane B2-d₉ is deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation .

HY-113331S

Thromboxane B2-d4	Isotope-Labeled Compounds	Inflammation/Immunology
Thromboxane B2-D4 is the deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation .

HY-18342S

Diflunisal-d3 MK-647-d₃	Isotope-Labeled Compounds COX	Inflammation/Immunology Cancer
Diflunisal-d₃ is the deuterium labeled Diflunisal. Diflunisal (MK-647) is a salicylate derivative with nonsteroidal anti-inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor.

HY-150773S1

Guanosine triphosphate-d14 dilithium GTP-d14 dilithium	Isotope-Labeled Compounds SARS-CoV Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Infection Cancer
Guanosine triphosphate-d₁₄ (GTP-d₁₄) dilithium is a deuterium labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19 .

HY-W007798S1

Fmoc-Cys(Trt)-OH-d2	Isotope-Labeled Compounds	Others
Fmoc-Cys(Trt)-OH-d₂ is the deuterium labeled Fmoc-Cys(Trt)-OH. Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative .

HY-N1914S

Ergothioneine-d3 L-(+)-Ergothioneine-d₃	Isotope-Labeled Compounds Endogenous Metabolite	Others
Ergothioneine-d₃ is the deuterium labeled Ergothioneine. Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant .

HY-15127S

Isotretinoin-d5	Isotope-Labeled Compounds RAR/RXR Endogenous Metabolite Autophagy	Cancer
Isotretinoin-d₅ is the deuterium labeled Isotretinoin. Isotretinoin is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity .

HY-A0163S

Zuclopenthixol-d4 succinate salt	Dopamine Receptor	Neurological Disease
Zuclopenthixol-d₄ succinate is the deuterium labeled Zuclopenthixol. Zuclopenthixol is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist .

HY-102015S

6-Biopterin-d3 L-Biopterin-d₃	Isotope-Labeled Compounds NO Synthase Endogenous Metabolite	Neurological Disease Cancer
6-Biopterin-d₃ (L-Biopterin-d₃) is deuterium labeled 6-Biopterin. 6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor .

HY-B0556AS

Tetrahydrozoline-d4 hydrochloride Tetryzoline-d4 hydrochloride	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease Endocrinology
Tetrahydrozoline-d₄ (hydrochloride) is the deuterium labeled Tetrahydrozoline hydrochloride. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .

HY-W738775

DL-3-Phenylalanine-d2 DLPA-d₂; NSC 9959-d₂	Isotope-Labeled Compounds Amino Acid Derivatives	Others
DL-3-Phenylalanine-d₂ (DLPA-d₂) is the deuterium labeled DL-3-Phenylalanine (HY-B1732). DL-3-Phenylalanine is a phenylalanine derivative .

HY-158995S

3-Epiglycyrrhetinic acid-d2 3α-Glycyrrhetic acid-d₂	Isotope-Labeled Compounds	Others
3-Epiglycyrrhetinic acid-d2 (3α-Glycyrrhetic acid-d2) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-158995S1

3-Epiglycyrrhetinic acid-d3 3α-Glycyrrhetic acid-d₃	Isotope-Labeled Compounds	Others
3-Epiglycyrrhetinic acid-d3 (3α-Glycyrrhetic acid-d3) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-B0479S1

Thiamphenicol-d3-1 Thiophenicol-d₃-1; Dextrosulphenidol-d₃-1	Isotope-Labeled Compounds	Infection
Thiamphenicol-d₃-1 (Thiophenicol-d₃-1; Dextrosulphenidol-d₃-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol)，a methyl-sulfonyl derivative of Chloramphenicol，is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit，leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative，Gram-positive aerobic and anaerobic bacteria) .

HY-144378S

Thiorphan methoxyacetophenone derivative-d7	Isotope-Labeled Compounds	Others
Thiorphan methoxyacetophenone derivative-d₇ is the deuterium labeled Thiorphan methoxyacetophenone derivative .

HY-Y1838S

Methoxytrimethylsilane-d3	Isotope-Labeled Compounds	Others
Methoxytrimethylsilane-d₃ is the deuterium labeled Methoxytrimethylsilane. Methoxytrimethylsilane is a mono-alkoxy derivative .

HY-113404S

DL-Dopa-d6	Isotope-Labeled Compounds Endogenous Metabolite	Others
DL-Dopa-d₆ is the deuterium labeled DL-Dopa. DL-Dopa is a beta-hydroxylated derivative of phenylalanine.

HY-W013998S

Glycyl-L-phenylalanine-d2 Gly-Phe-d₂; H-Gly-Phe-OH-d₂	Isotope-Labeled Compounds Amino Acid Derivatives	Others
Glycyl-L-phenylalanine-d₂ is a deuterium labeled Glycyl-L-phenylalanine (HY-W013998). Glycyl-L-phenylalanine is a phenylalanine derivative.

HY-Y1139S

Pimelic acid-d4 Heptanedioic acid-d₄; 1,5-Pentanedicarboxylic acid-d₄; 1,7-Heptanedioic acid-d₄	Endogenous Metabolite	Metabolic Disease
Pimelic acid-d₄ is the deuterium labeled Pimelic acid . Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.

HY-I0960S7

Uracil-d1	Endogenous Metabolite	Cancer
Uracil-d₁ is the deuterium labeled Uracil . Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA .

HY-100977S

Dimethoxycurcumin-d6 DiMC-d₆; CHC 004-d₆; Di-O-methylcurcumin-d₆	Isotope-Labeled Compounds	Inflammation/Immunology
Dimethoxycurcumin-d₆ is the deuterium labeled Dimethoxycurcumin (HY-100977). Dimethoxycurcumin is a derivative of Curcumin that has anti-inflammatory and antioxidant activities .

HY-W738325

H-Phe-OMe.hydrochloride-d5	Isotope-Labeled Compounds Amino Acid Derivatives	Others
H-Phe-OMe.hydrochloride-d₅ is the deuterium labeled H-Phe-OMe.hydrochloride (HY-Y1394). H-Phe-OMe.hydrochloride is a phenylalanine derivative .

HY-B0098S

Doxazosin-d8 UK 33274-d₈	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease Endocrinology
Doxazosin-d₈ is a deuterium labeled Doxazosin (UK 33274). Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic α1 adrenergic receptors .

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