3-Methyl-D-histidine-d3 hydrochloride
Based on 1 Customer Validation
3-Methyl-D-histidine-d3 hydrochloride is the deuterium labeled 3-Methyl-D-histidine hydrochloride. 3-Methyl-D-histidine hydrochloride can be found in actin and myosin and is a derivative of histidine.
For research use only. We do not sell to patients.
- Purity: 96.07%
- Formula: C7H9D3ClN3O2
- Molecular Weight:208.66
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Endogenous Metabolite Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 163750-76-3
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Appearance Solid
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Molecular Weight 208.66
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Formula C7H9D3ClN3O2
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Color White to off-white
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SMILES
OC([C@H](N)CC1=CN=CN1C([2H])([2H])[2H])=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (479.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. White WJ, Lawrie RA. Variations in the levels of 3-methyl-l-histidine of the myosins within the bovine carcass. Meat Sci. 1985;15(3):173-81. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7925 mL | 23.9624 mL | 47.9249 mL | 119.8121 mL |
| 5 mM | 0.9585 mL | 4.7925 mL | 9.5850 mL | 23.9624 mL | |
| 10 mM | 0.4792 mL | 2.3962 mL | 4.7925 mL | 11.9812 mL | |
| 15 mM | 0.3195 mL | 1.5975 mL | 3.1950 mL | 7.9875 mL | |
| 20 mM | 0.2396 mL | 1.1981 mL | 2.3962 mL | 5.9906 mL | |
| 25 mM | 0.1917 mL | 0.9585 mL | 1.9170 mL | 4.7925 mL | |
| 30 mM | 0.1597 mL | 0.7987 mL | 1.5975 mL | 3.9937 mL | |
| 40 mM | 0.1198 mL | 0.5991 mL | 1.1981 mL | 2.9953 mL | |
| 50 mM | 0.0958 mL | 0.4792 mL | 0.9585 mL | 2.3962 mL | |
| 60 mM | 0.0799 mL | 0.3994 mL | 0.7987 mL | 1.9969 mL | |
| 80 mM | 0.0599 mL | 0.2995 mL | 0.5991 mL | 1.4977 mL | |
| 100 mM | 0.0479 mL | 0.2396 mL | 0.4792 mL | 1.1981 mL |